microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3158-1 Gene

Subcategory (RNA class) for MIR3158-1 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR3158-1 Gene

  • MicroRNA 3158-1 2 3 5
  • Hsa-MiR-3158-3p 163 173
  • Hsa-Mir-3158-1 2 3
  • MIR3158-1 2 5
  • MIMAT0019211 50
  • MIMAT0015032 50
  • Mir-3158-1 3
  • MI0014186 50

External Ids for MIR3158-1 Gene

Previous GeneCards Identifiers for MIR3158-1 Gene

  • GC10U901357
  • GC10P103361

Summaries for MIR3158-1 Gene

Entrez Gene Summary for MIR3158-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3158-1 Gene

MIR3158-1 (MicroRNA 3158-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3158-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3158-1 Gene

Genomics for MIR3158-1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3158-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J101602 Enhancer 0.8 ENCODE 600.7 +1.5 1492 0.2 CTCF PRDM10 ZNF692 ZNF143 ZNF24 REST RAD21 TRIM22 YY1 NRF1 MIR3158-1 MIR3158-2 POLL lnc-POLL-1 DPCD FBXW4
GH10J101601 Enhancer 0.5 Ensembl 600.7 0.0 -16 0.4 ZFX ESR1 ATF2 ZFP69B SP7 MIR3158-1 MIR3158-2 POLL lnc-BTRC-4 DPCD FBXW4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3158-1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3158-1 Gene

Genomic Locations for MIR3158-1 Gene
chr10:101,601,417-101,601,497
(GRCh38/hg38)
Size:
81 bases
Orientation:
Plus strand
chr10:103,361,174-103,361,254
(GRCh37/hg19)
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR3158-1 Gene

Genes around MIR3158-1 on UCSC Golden Path with GeneCards custom track
MIR3158-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3158-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3158-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3158-1 Gene

Proteins for MIR3158-1 Gene

Post-translational modifications for MIR3158-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3158-1 Gene

Domains & Families for MIR3158-1 Gene

Gene Families for MIR3158-1 Gene

HGNC:
genes like me logo Genes that share domains with MIR3158-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3158-1 Gene

Function for MIR3158-1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3158-1 Gene

Localization for MIR3158-1 Gene

Gene Ontology (GO) - Cellular Components for MIR3158-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR3158-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3158-1 Gene

Pathways & Interactions for MIR3158-1 Gene

PathCards logo

SuperPathways for MIR3158-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3158-1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3158-1 Gene

Drugs & Compounds for MIR3158-1 Gene

No Compound Related Data Available

Transcripts for MIR3158-1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3158-1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075F122_9606 precursor_RNA 81 5

HGNC: 38196,

RefSeq: NR_036114,

Ensembl: ENST00000583596 (view in UCSC) ,

miRBase: MI0014186,

ENA: LM611011.1:1..81:precursor_RNA,

URS000040D577_9606 miRNA 22 5

RefSeq: NR_036114, NR_036115,

LncBase: hsa-miR-3158-3p,

miRBase: MIMAT0015032,

TarBase: hsa-miR-3158-3p,

ENA: FR772748.1:1..22:ncRNA, LM381655.1:1..22:ncRNA, LM611011.1:50..71:ncRNA, LM611012.1:50..71:ncRNA,

URS0000221D0E_9606 miRNA 21 3

RefSeq: NR_036114, NR_036115,

miRBase: MIMAT0019211,

ENA: FR772749.1:1..21:ncRNA, LM611011.1:13..33:ncRNA, LM611012.1:13..33:ncRNA,

MIR3158-1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3158-1 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3158-1 Gene

No ASD Table

Relevant External Links for MIR3158-1 Gene

GeneLoc Exon Structure for
MIR3158-1

Expression for MIR3158-1 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3158-1 Gene

Orthologs for MIR3158-1 Gene

Evolution for MIR3158-1 Gene

ENSEMBL:
Gene Tree for MIR3158-1 (if available)
TreeFam:
Gene Tree for MIR3158-1 (if available)

No data available for Orthologs for MIR3158-1 Gene

Paralogs for MIR3158-1 Gene

No data available for Paralogs for MIR3158-1 Gene

Variants for MIR3158-1 Gene

Additional dbSNP identifiers (rs#s) for MIR3158-1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3158-1 Gene

Variant ID Type Subtype PubMed ID
esv2750847 CNV gain 17911159
esv3624382 CNV gain 21293372
nsv1053934 CNV gain 25217958
nsv527185 CNV loss 19592680

Additional Variant Information for MIR3158-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3158-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3158-1 Gene

Disorders for MIR3158-1 Gene

Additional Disease Information for MIR3158-1

No disorders were found for MIR3158-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3158-1 Gene

Publications for MIR3158-1 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3

Products for MIR3158-1 Gene

Sources for MIR3158-1 Gene