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Aliases for MIR3157 Gene

Subcategory (RNA class) for MIR3157 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3157 Gene

  • MicroRNA 3157 2 3 5
  • Hsa-Mir-3157 3
  • Mir-3157 3

External Ids for MIR3157 Gene

Previous GeneCards Identifiers for MIR3157 Gene

  • GC10U901401
  • GC10M097824

Summaries for MIR3157 Gene

Entrez Gene Summary for MIR3157 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3157 Gene

MIR3157 (MicroRNA 3157) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3157 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3157 Gene

Genomics for MIR3157 Gene

GeneHancer (GH) Regulatory Elements for MIR3157 Gene

Promoters and enhancers for MIR3157 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I096065 Enhancer 0.7 ENCODE 550.8 -1.4 -1435 1.3 TAF9B JUN NFRKB ZNF384 E4F1 E2F1 CC2D1A POLR2A ZSCAN29 PRDM10 MIR3157 ENTPD1-AS1 ZNF518A GC10P096083
GH10I096042 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.3 +20.2 20159 2.8 HDGF ARID4B SIN3A ZNF2 YY1 ZNF207 ZNF143 FOS SP3 NFYC CCNJ ZNF518A TCTN3 MIR3157 ENTPD1-AS1
GH10I096072 Enhancer 0.7 ENCODE 0.4 -8.5 -8480 0.2 MEIS2 PKNOX1 TEAD4 TAL1 E4F1 TCF12 CTBP1 NCOR1 CBFA2T2 SMARCE1 RNU6-271P MIR3157 GC10P096083 ENTPD1-AS1
GH10I096073 Enhancer 0.6 ENCODE 0.4 -9.2 -9160 0.4 SMARCE1 PKNOX1 RFX1 JUN CBFA2T3 DPF2 FOSL1 JUND IKZF1 CREB1 RNU6-271P GC10P096083 MIR3157 ENTPD1-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3157 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3157 Gene

Genomic Locations for MIR3157 Gene
chr10:96,064,315-96,064,399
(GRCh38/hg38)
Size:
85 bases
Orientation:
Minus strand
chr10:97,824,072-97,824,156
(GRCh37/hg19)

Genomic View for MIR3157 Gene

Genes around MIR3157 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3157 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3157 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3157 Gene

ORGUL Member Location for MIR3157 Gene

ORGUL Member Location for MIR3157 gene

Proteins for MIR3157 Gene

Post-translational modifications for MIR3157 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3157 Gene

Domains & Families for MIR3157 Gene

Gene Families for MIR3157 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3157: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3157 Gene

Function for MIR3157 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3157 Gene

Localization for MIR3157 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3157 Gene

Pathways & Interactions for MIR3157 Gene

SuperPathways for MIR3157 Gene

No Data Available

Interacting Proteins for MIR3157 Gene

Gene Ontology (GO) - Biological Process for MIR3157 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3157 Gene

Drugs & Compounds for MIR3157 Gene

No Compound Related Data Available

Transcripts for MIR3157 Gene

mRNA/cDNA for MIR3157 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3157 Gene

No ASD Table

Relevant External Links for MIR3157 Gene

GeneLoc Exon Structure for
MIR3157
ECgene alternative splicing isoforms for
MIR3157

Expression for MIR3157 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3157 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3157 Gene:

MIR3157
genes like me logo Genes that share expression patterns with MIR3157: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3157 Gene

Orthologs for MIR3157 Gene

Evolution for MIR3157 Gene

ENSEMBL:
Gene Tree for MIR3157 (if available)
TreeFam:
Gene Tree for MIR3157 (if available)

No data available for Orthologs for MIR3157 Gene

Paralogs for MIR3157 Gene

No data available for Paralogs for MIR3157 Gene

Variants for MIR3157 Gene

Sequence variations from dbSNP and Humsavar for MIR3157 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000396817 -- 96,066,113(-) T/G upstream_transcript_variant
rs1001127169 -- 96,065,681(-) G/A upstream_transcript_variant
rs1002627337 -- 96,063,865(-) C/T downstream_transcript_variant
rs1002896634 -- 96,063,976(-) T/C downstream_transcript_variant
rs1002986497 -- 96,064,251(-) AAGAG/ downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3157 Gene

Variant ID Type Subtype PubMed ID
nsv1110852 OTHER inversion 24896259

Additional Variant Information for MIR3157 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3157

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3157 Gene

Disorders for MIR3157 Gene

Additional Disease Information for MIR3157

No disorders were found for MIR3157 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3157 Gene

Publications for MIR3157 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3157 Gene

Sources for MIR3157 Gene

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