microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3157 Gene

Subcategory (RNA class) for MIR3157 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR3157 Gene

  • MicroRNA 3157 2 3 5
  • Hsa-MiR-3157-3p 166 177
  • Hsa-MiR-3157-5p 166 177
  • Hsa-Mir-3157 3
  • MIMAT0015031 51
  • MIMAT0019210 51
  • MI0014185 51
  • Mir-3157 3
  • MIR3157 2

External Ids for MIR3157 Gene

Previous GeneCards Identifiers for MIR3157 Gene

  • GC10U901401
  • GC10M097824

Summaries for MIR3157 Gene

Entrez Gene Summary for MIR3157 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3157 Gene

MIR3157 (MicroRNA 3157) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3157 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3157 Gene

Genomics for MIR3157 Gene

GeneHancer (GH) Regulatory Elements for MIR3157 Gene

Promoters and enhancers for MIR3157 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J096065 Enhancer 0.9 Ensembl ENCODE 500.7 -1.3 -1302 1.8 ZBTB5 AFF1 TOE1 NFRKB TAF9B KDM5B TCF7L2 IRF1 POLR2H TBP MIR3157 RNU6-271P ENTPD1-AS1 ZNF518A lnc-CCNJ-2
GH10J096072 Enhancer 0.9 Ensembl ENCODE 0.4 -9.5 -9502 5 JUND MYC CTBP1 NR2F2 NCOR1 CREB1 NFIC FOS CEBPB PBX2 CCNJ ZNF518A RNU6-271P BLNK CC2D2B ENTPD1-AS1 MIR3157 lnc-CCNJ-2
GH10J096053 Enhancer 0.4 Ensembl 0.4 +11.0 10998 4.4 NR2F2 GATA2 JUN POLR2A PRDM1 RNU6-271P ENTPD1-AS1 ZNF518A CC2D2B piR-38344-014 MIR3157 CCNJ
GH10J096049 Enhancer 0.3 Ensembl 0.4 +15.0 14998 0.8 TBX21 IKZF1 piR-38344-014 piR-38351-057 ZNF518A CCNJ MIR3157 ENTPD1-AS1
GH10J096048 Enhancer 0.3 Ensembl 0.4 +16.0 15998 0.4 ZNF146 piR-38344-014 piR-38351-057 ENTPD1-AS1 ZNF518A CCNJ MIR3157
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3157 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3157 Gene

Genomic Locations for MIR3157 Gene
chr10:96,064,315-96,064,399
(GRCh38/hg38)
Size:
85 bases
Orientation:
Minus strand
chr10:97,824,072-97,824,156
(GRCh37/hg19)
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR3157 Gene

Genes around MIR3157 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3157 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3157 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3157 Gene

Proteins for MIR3157 Gene

Post-translational modifications for MIR3157 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3157 Gene

Domains & Families for MIR3157 Gene

Gene Families for MIR3157 Gene

HGNC:
genes like me logo Genes that share domains with MIR3157: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3157 Gene

Function for MIR3157 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3157 Gene

Localization for MIR3157 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3157 gene
Compartment Confidence
cytoskeleton 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3157 Gene

Pathways & Interactions for MIR3157 Gene

PathCards logo

SuperPathways for MIR3157 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR3157 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3157 Gene

Drugs & Compounds for MIR3157 Gene

No Compound Related Data Available

Transcripts for MIR3157 Gene

mRNA/cDNA for MIR3157 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
6 ENA transcripts :
2 LncBase transcripts :
2 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3157 Gene

No ASD Table

Relevant External Links for MIR3157 Gene

GeneLoc Exon Structure for
MIR3157

Expression for MIR3157 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3157 Gene

genes like me logo Genes that share expression patterns with MIR3157: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3157 Gene

Orthologs for MIR3157 Gene

Evolution for MIR3157 Gene

ENSEMBL:
Gene Tree for MIR3157 (if available)
TreeFam:
Gene Tree for MIR3157 (if available)

No data available for Orthologs for MIR3157 Gene

Paralogs for MIR3157 Gene

No data available for Paralogs for MIR3157 Gene

Variants for MIR3157 Gene

Additional dbSNP identifiers (rs#s) for MIR3157 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3157 Gene

Variant ID Type Subtype PubMed ID
nsv1110852 OTHER inversion 24896259

Additional Variant Information for MIR3157 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3157

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3157 Gene

Disorders for MIR3157 Gene

Additional Disease Information for MIR3157

No disorders were found for MIR3157 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3157 Gene

Publications for MIR3157 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 54
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR3157 Gene

Sources for MIR3157 Gene