Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3143 Gene

Subcategory (RNA class) for MIR3143 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3143 Gene

  • MicroRNA 3143 2 3 5
  • Hsa-Mir-3143 3
  • Mir-3143 3

External Ids for MIR3143 Gene

Previous GeneCards Identifiers for MIR3143 Gene

  • GC06U901957
  • GC06P027115
  • GC06P027149

Summaries for MIR3143 Gene

Entrez Gene Summary for MIR3143 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3143 Gene

MIR3143 (MicroRNA 3143) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3143 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3143 Gene

Genomics for MIR3143 Gene

GeneHancer (GH) Regulatory Elements for MIR3143 Gene

Promoters and enhancers for MIR3143 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I027126 Promoter/Enhancer 2.6 EPDnew Ensembl ENCODE dbSUPER 0.4 -9.6 -9604 23 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC HIST1H2AH GC06P027140 HIST1H2AG HIST1H4I HIST1H2BK HIST1H2BJ ZKSCAN8 ABT1 HMGN4 BTN2A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3143 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3143 Gene

Genomic Locations for MIR3143 Gene
chr6:27,147,626-27,147,688
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand
chr6:27,115,405-27,115,467
(GRCh37/hg19)

Genomic View for MIR3143 Gene

Genes around MIR3143 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3143 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3143 Gene

Proteins for MIR3143 Gene

Post-translational modifications for MIR3143 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3143 Gene

Domains & Families for MIR3143 Gene

Gene Families for MIR3143 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3143: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3143 Gene

Function for MIR3143 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3143 Gene

Localization for MIR3143 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3143 Gene

Pathways & Interactions for MIR3143 Gene

SuperPathways for MIR3143 Gene

No Data Available

Interacting Proteins for MIR3143 Gene

Gene Ontology (GO) - Biological Process for MIR3143 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3143 Gene

Drugs & Compounds for MIR3143 Gene

No Compound Related Data Available

Transcripts for MIR3143 Gene

mRNA/cDNA for MIR3143 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3143 Gene

No ASD Table

Relevant External Links for MIR3143 Gene

GeneLoc Exon Structure for
MIR3143
ECgene alternative splicing isoforms for
MIR3143

Expression for MIR3143 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3143 Gene:

MIR3143
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3143 Gene

Orthologs for MIR3143 Gene

Evolution for MIR3143 Gene

ENSEMBL:
Gene Tree for MIR3143 (if available)
TreeFam:
Gene Tree for MIR3143 (if available)

No data available for Orthologs for MIR3143 Gene

Paralogs for MIR3143 Gene

No data available for Paralogs for MIR3143 Gene

Variants for MIR3143 Gene

Sequence variations from dbSNP and Humsavar for MIR3143 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000523775 -- 27,147,863(+) C/T downstream_transcript_variant
rs1001361991 -- 27,148,034(+) G/C downstream_transcript_variant
rs1001502335 -- 27,147,739(+) C/T downstream_transcript_variant
rs1001641087 -- 27,145,697(+) A/G upstream_transcript_variant
rs1003560703 -- 27,147,037(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3143 Gene

Variant ID Type Subtype PubMed ID
nsv970091 CNV duplication 23825009

Additional Variant Information for MIR3143 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3143

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3143 Gene

Disorders for MIR3143 Gene

Additional Disease Information for MIR3143

No disorders were found for MIR3143 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3143 Gene

Publications for MIR3143 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3143 Gene

Sources for MIR3143 Gene

Content
Loading form....