microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3143 Gene

Subcategory (RNA class) for MIR3143 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR3143 Gene

  • MicroRNA 3143 2 3 5
  • Hsa-Mir-3143 2 3
  • MIR3143 2 5
  • MIMAT0015012 50
  • Hsa-MiR-3143 173
  • MI0014167 50
  • Mir-3143 3

External Ids for MIR3143 Gene

Previous GeneCards Identifiers for MIR3143 Gene

  • GC06U901957
  • GC06P027115
  • GC06P027149
  • GC06P027394
  • GC06P027547
  • GC06P027604
  • GC06P028055
  • GC06P027153
  • GC06P027193
  • GC06P027311

Summaries for MIR3143 Gene

Entrez Gene Summary for MIR3143 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3143 Gene

MIR3143 (MicroRNA 3143) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3143 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3143 Gene

Genomics for MIR3143 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3143 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J027126 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -9.6 -9604 23 BRCA1 ARHGAP35 CEBPG SP1 HNRNPL CREB1 GATAD2A CTCF ATF7 PRDM10 H4C9 H2BC11 ABT1 HMGN4 BTN2A2 BTN2A1 ZNF322 ENSG00000261584 BTN2A3P GUSBP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3143 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3143 Gene

Genomic Locations for MIR3143 Gene
chr6:27,147,626-27,147,688
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand
chr6:27,115,405-27,115,467
(GRCh37/hg19)
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR3143 Gene

Genes around MIR3143 on UCSC Golden Path with GeneCards custom track
MIR3143 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3143 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3143 Gene

Proteins for MIR3143 Gene

Post-translational modifications for MIR3143 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3143 Gene

Domains & Families for MIR3143 Gene

Gene Families for MIR3143 Gene

HGNC:
genes like me logo Genes that share domains with MIR3143: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3143 Gene

Function for MIR3143 Gene

Phenotypes From GWAS Catalog for MIR3143 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3143 Gene

Localization for MIR3143 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3143 Gene

Pathways & Interactions for MIR3143 Gene

PathCards logo

SuperPathways for MIR3143 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3143 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3143 Gene

Drugs & Compounds for MIR3143 Gene

No Compound Related Data Available

Transcripts for MIR3143 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3143 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000759A9E_9606 precursor_RNA 63 5

HGNC: 38284,

RefSeq: NR_036096,

Ensembl: ENST00000584253 (view in UCSC) ,

miRBase: MI0014167,

ENA: LM610993.1:1..63:precursor_RNA,

URS0000610EFA_9606 miRNA 25 4

RefSeq: NR_036096,

miRBase: MIMAT0015012,

TarBase: hsa-miR-3143,

ENA: LM381637.1:1..25:ncRNA, LM610993.1:4..28:ncRNA,

URS0000358283_9606 miRNA 22 1

ENA: FR772733.1:1..22:ncRNA,

MIR3143 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3143 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3143 Gene

No ASD Table

Relevant External Links for MIR3143 Gene

GeneLoc Exon Structure for
MIR3143

Expression for MIR3143 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR3143

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3143 Gene

Orthologs for MIR3143 Gene

Evolution for MIR3143 Gene

ENSEMBL:
Gene Tree for MIR3143 (if available)
TreeFam:
Gene Tree for MIR3143 (if available)

No data available for Orthologs for MIR3143 Gene

Paralogs for MIR3143 Gene

No data available for Paralogs for MIR3143 Gene

Variants for MIR3143 Gene

Additional dbSNP identifiers (rs#s) for MIR3143 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3143 Gene

Variant ID Type Subtype PubMed ID
nsv970091 CNV duplication 23825009

Additional Variant Information for MIR3143 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3143

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3143 Gene

Disorders for MIR3143 Gene

Additional Disease Information for MIR3143

No disorders were found for MIR3143 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3143 Gene

Publications for MIR3143 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3143 Gene

Sources for MIR3143 Gene