microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3138 Gene

Subcategory (RNA class) for MIR3138 Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR3138 Gene

  • MicroRNA 3138 2 3 5
  • Hsa-Mir-3138 2 3 178
  • Hsa-MiR-3138 163 173
  • MIR3138 2 5
  • MIMAT0015006 50
  • MI0014161 50
  • Mir-3138 3

External Ids for MIR3138 Gene

Previous GeneCards Identifiers for MIR3138 Gene

  • GC04U901261
  • GC04M009413

Summaries for MIR3138 Gene

Entrez Gene Summary for MIR3138 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3138 Gene

MIR3138 (MicroRNA 3138) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3138 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3138 Gene

Genomics for MIR3138 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3138 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J010074 Enhancer 0.7 dbSUPER 600.7 +0.5 523 7 CTCF IKZF1 POLR2A JUND SMAD5 FOS RBM22 FOSL1 RCOR1 FOSL2 MIR3138 SLC2A9 WDR1 RNA5SP155 ENSG00000261490 lnc-SLC2A9-3
GH04J010087 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -10.4 -10442 3.2 CTCF POLR2A ZIC2 RBM22 RAD21 ZNF143 SLC2A9 RNA5SP155 WDR1 ENSG00000261490 ENSG00000250413 lnc-SLC2A9-4 MIR3138
GH04J010081 Enhancer 0.3 dbSUPER 0.7 -4.2 -4211 2.5 POLR2A RBM22 SLC2A9 WDR1 RNA5SP155 ENSG00000261490 MIR3138 lnc-SLC2A9-4
GH04J010084 Enhancer 0.4 ENCODE dbSUPER 0.4 -6.5 -6524 1.7 NFATC1 SLC2A9 WDR1 RNA5SP155 ENSG00000261490 ENSG00000250413 MIR3138 lnc-SLC2A9-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3138 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3138 Gene

Genomic Locations for MIR3138 Gene
chr4:10,078,611-10,078,692
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand
chr4:10,080,235-10,080,316
(GRCh37/hg19)
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR3138 Gene

Genes around MIR3138 on UCSC Golden Path with GeneCards custom track
MIR3138 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR3138 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3138 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3138 Gene

Proteins for MIR3138 Gene

Post-translational modifications for MIR3138 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3138 Gene

Domains & Families for MIR3138 Gene

Gene Families for MIR3138 Gene

HGNC:
genes like me logo Genes that share domains with MIR3138: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3138 Gene

Function for MIR3138 Gene

Phenotypes From GWAS Catalog for MIR3138 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3138 Gene

Localization for MIR3138 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3138 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3138 Gene

Pathways & Interactions for MIR3138 Gene

PathCards logo

SuperPathways for MIR3138 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3138 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3138 Gene

Drugs & Compounds for MIR3138 Gene

No Compound Related Data Available

Transcripts for MIR3138 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3138 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E93A_9606 precursor_RNA 82 5

HGNC: 38341,

RefSeq: NR_036090,

Ensembl: ENST00000585238 (view in UCSC) ,

miRBase: MI0014161,

ENA: LM610988.1:1..82:precursor_RNA,

URS00002C83DA_9606 miRNA 24 5

RefSeq: NR_036090,

LncBase: hsa-miR-3138,

miRBase: MIMAT0015006,

TarBase: hsa-miR-3138,

ENA: LM381632.1:1..24:ncRNA, LM610988.1:48..71:ncRNA,

URS0000EFDEE1_9606 precursor_RNA 63 1

MirGeneDB: Hsa-Mir-3138,

URS0000EFC6B0_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-3138_3p,

URS0000EFDA9B_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-3138_5p,

MIR3138 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3138 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3138 Gene

No ASD Table

Relevant External Links for MIR3138 Gene

GeneLoc Exon Structure for
MIR3138

Expression for MIR3138 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3138 Gene

genes like me logo Genes that share expression patterns with MIR3138: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3138 Gene

Orthologs for MIR3138 Gene

Evolution for MIR3138 Gene

ENSEMBL:
Gene Tree for MIR3138 (if available)
TreeFam:
Gene Tree for MIR3138 (if available)

No data available for Orthologs for MIR3138 Gene

Paralogs for MIR3138 Gene

No data available for Paralogs for MIR3138 Gene

Variants for MIR3138 Gene

Additional dbSNP identifiers (rs#s) for MIR3138 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR3138 Gene

Variant ID Type Subtype PubMed ID
dgv5117n100 CNV gain 25217958
esv2752052 CNV gain 17911159
esv2759222 CNV gain+loss 17122850
esv3599589 CNV gain 21293372
esv3599598 CNV gain 21293372
nsv1005698 CNV gain 25217958
nsv1013487 CNV gain 25217958
nsv1014335 CNV gain 25217958
nsv428438 CNV gain 18775914
nsv469621 CNV loss 16826518
nsv829857 CNV gain 17160897

Additional Variant Information for MIR3138 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3138

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3138 Gene

Disorders for MIR3138 Gene

Additional Disease Information for MIR3138

No disorders were found for MIR3138 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3138 Gene

Publications for MIR3138 Gene

  1. MicroRNA expression profiles in pediatric dysembryoplastic neuroepithelial tumors. (PMID: 26698155) Braoudaki M … Kanavakis E (Medical oncology (Northwood, London, England) 2016) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3138 Gene

Sources for MIR3138 Gene