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microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR3138 Gene
Subcategory (RNA class) for MIR3138 Gene
miRNA
Number of RNA Genes sources:
5 / 17
Aliases for MIR3138 Gene
External Ids for MIR3138 Gene
- HGNC: 38341
- Entrez Gene: 100423011
- Ensembl: ENSG00000264931
- miRBase: hsa-mir-3138
Previous GeneCards Identifiers for MIR3138 Gene
- GC04U901261
- GC04M009413
Summaries for MIR3138 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR3138 Gene
MIR3138 (MicroRNA 3138) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR3138 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3138 Gene
Genomics for MIR3138 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MIR3138 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04J010074 | Enhancer | 0.7 | dbSUPER | 600.7 | +0.5 | 523 | 7 | CTCF IKZF1 POLR2A JUND SMAD5 FOS RBM22 FOSL1 RCOR1 FOSL2 | MIR3138 SLC2A9 WDR1 RNA5SP155 ENSG00000261490 lnc-SLC2A9-3 | |
| GH04J010087 | Enhancer | 0.8 | Ensembl ENCODE dbSUPER | 0.4 | -10.4 | -10442 | 3.2 | CTCF POLR2A ZIC2 RBM22 RAD21 ZNF143 | SLC2A9 RNA5SP155 WDR1 ENSG00000261490 ENSG00000250413 lnc-SLC2A9-4 MIR3138 | |
| GH04J010081 | Enhancer | 0.3 | dbSUPER | 0.7 | -4.2 | -4211 | 2.5 | POLR2A RBM22 | SLC2A9 WDR1 RNA5SP155 ENSG00000261490 MIR3138 lnc-SLC2A9-4 | |
| GH04J010084 | Enhancer | 0.4 | ENCODE dbSUPER | 0.4 | -6.5 | -6524 | 1.7 | NFATC1 | SLC2A9 WDR1 RNA5SP155 ENSG00000261490 ENSG00000250413 MIR3138 lnc-SLC2A9-4 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR3138 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for MIR3138 Gene
Genomic Locations for MIR3138 Gene
- chr4:10,078,611-10,078,692
- (GRCh38/hg38)
- Size:
- 82 bases
- Orientation:
- Minus strand
- chr4:10,080,235-10,080,316
- (GRCh37/hg19)
- Size:
- 82 bases
- Orientation:
- Minus strand
Genomic View for MIR3138 Gene
Genes around MIR3138 on UCSC Golden Path with GeneCards custom track
MIR3138 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 4p16.1 by HGNC
- 4p16.1 by Entrez Gene
- 4p16.1 by Ensembl
MIR3138 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR3138 Gene
Proteins for MIR3138 Gene
Post-translational modifications for MIR3138 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3138
- Origene Custom Protein Services for MIR3138
No data available for DME Specific Peptides for MIR3138 Gene
Domains & Families for MIR3138 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3138 Gene
Function for MIR3138 Gene
Phenotypes From GWAS Catalog for MIR3138 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR3138 - Select products 50% OFF >
- * MIR3138 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR3138
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR3138 - Select products 50% OFF >
- * MIR3138 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3138 Gene
Localization for MIR3138 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3138 Gene
Transcripts for MIR3138 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3138 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000075E93A_9606 | precursor_RNA | 82 | 5 |
HGNC: 38341, RefSeq: NR_036090, Ensembl: ENST00000585238 (view in UCSC) , miRBase: MI0014161, |
| URS00002C83DA_9606 | miRNA | 24 | 5 |
RefSeq: NR_036090, LncBase: hsa-miR-3138, miRBase: MIMAT0015006, TarBase: hsa-miR-3138, |
| URS0000EFDEE1_9606 | precursor_RNA | 63 | 1 |
MirGeneDB: Hsa-Mir-3138, |
| URS0000EFC6B0_9606 | miRNA | 21 | 1 |
MirGeneDB: Hsa-Mir-3138_3p, |
| URS0000EFDA9B_9606 | miRNA | 21 | 1 |
MirGeneDB: Hsa-Mir-3138_5p, |
MIR3138 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for MIR3138 Gene
- 1 NCBI additional mRNA sequence :
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MIR3138 - Select products 50% OFF >
- * MIR3138 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Browse CRISPR knockouts for MIR3138
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR3138 - Select products 50% OFF >
- * MIR3138 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
Relevant External Links for MIR3138 Gene
- GeneLoc Exon Structure for
- MIR3138
Expression for MIR3138 Gene
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3138 Gene
Orthologs for MIR3138 Gene
No data available for Orthologs for MIR3138 Gene
Paralogs for MIR3138 Gene
No data available for Paralogs for MIR3138 Gene
Variants for MIR3138 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5117n100 | CNV | gain | 25217958 |
| esv2752052 | CNV | gain | 17911159 |
| esv2759222 | CNV | gain+loss | 17122850 |
| esv3599589 | CNV | gain | 21293372 |
| esv3599598 | CNV | gain | 21293372 |
| nsv1005698 | CNV | gain | 25217958 |
| nsv1013487 | CNV | gain | 25217958 |
| nsv1014335 | CNV | gain | 25217958 |
| nsv428438 | CNV | gain | 18775914 |
| nsv469621 | CNV | loss | 16826518 |
| nsv829857 | CNV | gain | 17160897 |
Additional Variant Information for MIR3138 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR3138
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3138 Gene
Disorders for MIR3138 Gene
Additional Disease Information for MIR3138
No disorders were found for MIR3138 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3138 Gene
Publications for MIR3138 Gene
- MicroRNA expression profiles in pediatric dysembryoplastic neuroepithelial tumors. (PMID: 26698155) Braoudaki M … Kanavakis E (Medical oncology (Northwood, London, England) 2016) 3
- miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
- Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
- Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3
ExternalLinks
Products for MIR3138 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR3138
- Origene Custom Protein Services for MIR3138
- Browse OriGene Inhibitory RNA Products For MIR3138
- OriGene qPCR primer pairs for MIR3138
- Browse CRISPR knockouts for MIR3138
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR3138
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR3138
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR3138
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR3138
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR3138
Sources for MIR3138 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB