microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3131 Gene

Data sources for MIR3131 Gene:

RNA type for MIR3131 Gene

miRNA

Aliases for MIR3131 Gene

External Ids for MIR3131 Gene

Previous GeneCards Identifiers for MIR3131 Gene

  • GC02U902098
  • GC02M219923

Summaries for MIR3131 Gene

Entrez Gene Summary for MIR3131 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3131 Gene

MIR3131 (MicroRNA 3131) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3131 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3131 Gene

Genomics for MIR3131 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3131 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J219058 Promoter/Enhancer 1.4 Ensembl ENCODE dbSUPER 250.7 -1.1 -1074 3.4 EZH2 ZNF654 ZNF600 ZIC2 CTCF REST TARDBP SIN3A THAP11 FOXA2 IHH MIR3131 LOC100129175 MIR375 NHEJ1 SLC23A3 CFAP65
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3131 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3131 Gene

Latest Assembly
chr2:219,058,688-219,058,750
(GRCh38/hg38)
Size:
63 bases
Orientation:
Minus strand

Previous Assembly
chr2:219,923,410-219,923,472
(GRCh37/hg19 by Entrez Gene)
Size:
63 bases
Orientation:
Minus strand

chr2:219,923,410-219,923,472
(GRCh37/hg19 by Ensembl)
Size:
63 bases
Orientation:
Minus strand

Genomic View for MIR3131 Gene

Genes around MIR3131 on UCSC Golden Path with GeneCards custom track
MIR3131 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3131 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3131 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3131 Gene

Proteins for MIR3131 Gene

Post-translational modifications for MIR3131 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3131 Gene

Domains & Families for MIR3131 Gene

Gene Families for MIR3131 Gene

HGNC:
genes like me logo Genes that share domains with MIR3131: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3131 Gene

Function for MIR3131 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3131 Gene

Localization for MIR3131 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3131 Gene

Pathways & Interactions for MIR3131 Gene

PathCards logo

SuperPathways for MIR3131 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3131 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3131 Gene

Drugs & Compounds for MIR3131 Gene

No Compound Related Data Available

Transcripts for MIR3131 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3131 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075DAEA_9606 precursor_RNA 63 4

RefSeq: NR_036081,

Ensembl: ENST00000583592 (view in UCSC) ,

miRBase: MI0014151,

ENA: LM610979.1:1..63:precursor_RNA,

URS00000FB5B8_9606 miRNA 23 3

RefSeq: NR_036081,

miRBase: MIMAT0014996,

ENA: LM381623.1:1..23:ncRNA, LM610979.1:4..26:ncRNA,

URS000016E1E5_9606 miRNA 24 1

ENA: FR772728.1:1..24:ncRNA,

MIR3131 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3131 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3131 Gene

No ASD Table

Relevant External Links for MIR3131 Gene

GeneLoc Exon Structure for
MIR3131

Expression for MIR3131 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3131 Gene

Orthologs for MIR3131 Gene

Evolution for MIR3131 Gene

ENSEMBL:
Gene Tree for MIR3131 (if available)
TreeFam:
Gene Tree for MIR3131 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3131

No data available for Orthologs for MIR3131 Gene

Paralogs for MIR3131 Gene

No data available for Paralogs for MIR3131 Gene

Variants for MIR3131 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3131 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3131 Gene

Variant ID Type Subtype PubMed ID
nsv584491 CNV loss 21841781
nsv821902 CNV gain 20364138
nsv954840 CNV deletion 24416366

Additional Variant Information for MIR3131 Gene

Human Gene Mutation Database (HGMD)
MIR3131
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3131
Leiden Open Variation Database (LOVD)
MIR3131

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3131 Gene

Disorders for MIR3131 Gene

Additional Disease Information for MIR3131

No disorders were found for MIR3131 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3131 Gene

Publications for MIR3131 Gene

  1. An indel polymorphism within pre-miR3131 confers risk for hepatocellular carcinoma. (PMID: 28034876) Wang C … Gao Y (Carcinogenesis 2017) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3131 Gene

Sources for MIR3131 Gene