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Aliases for MIR3131 Gene

Subcategory (RNA class) for MIR3131 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3131 Gene

  • MicroRNA 3131 2 3 5
  • Hsa-Mir-3131 3
  • Mir-3131 3

External Ids for MIR3131 Gene

Previous GeneCards Identifiers for MIR3131 Gene

  • GC02U902098
  • GC02M219923

Summaries for MIR3131 Gene

Entrez Gene Summary for MIR3131 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3131 Gene

MIR3131 (MicroRNA 3131) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3131 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3131 Gene

Genomics for MIR3131 Gene

GeneHancer (GH) Regulatory Elements for MIR3131 Gene

Promoters and enhancers for MIR3131 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I219059 Enhancer 1.1 ENCODE dbSUPER 550.8 -1.2 -1162 3.3 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF48 SLC30A9 GLIS2 ARID2 ZNF143 IHH MIR3131 LOC100129175 MIR375 NHEJ1 SLC23A3
GH02I219058 Enhancer 1 ENCODE dbSUPER 550.8 +0.6 576 0.2 ELF3 RB1 ARID4B SIN3A ZNF48 RAD21 SLC30A9 ARID2 ZNF143 THAP11 MIR3131 LOC100129175 MIR375 IHH NHEJ1 CFAP65
GH02I219042 Enhancer 0.5 dbSUPER 0.4 +16.0 15997 1.6 TFAP4 USF1 SCRT2 MIER2 HNF4A ZNF644 CFAP65 NHEJ1 IHH SLC23A3 MIR3131
GH02I219049 Enhancer 0.3 dbSUPER 0.4 +8.9 8889 1 TFAP4 SLC23A3 LOC100129175 MIR375 ENSG00000235024 CDK5R2 CRYBA2 FEV LINC00608 NHEJ1 IHH
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3131 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3131 Gene

Genomic Locations for MIR3131 Gene
chr2:219,058,688-219,058,750
(GRCh38/hg38)
Size:
63 bases
Orientation:
Minus strand
chr2:219,923,410-219,923,472
(GRCh37/hg19)

Genomic View for MIR3131 Gene

Genes around MIR3131 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3131 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3131 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3131 Gene

Proteins for MIR3131 Gene

Post-translational modifications for MIR3131 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3131 Gene

Domains & Families for MIR3131 Gene

Gene Families for MIR3131 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3131: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3131 Gene

Function for MIR3131 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3131 Gene

Localization for MIR3131 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3131 Gene

Pathways & Interactions for MIR3131 Gene

SuperPathways for MIR3131 Gene

No Data Available

Interacting Proteins for MIR3131 Gene

Gene Ontology (GO) - Biological Process for MIR3131 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3131 Gene

Drugs & Compounds for MIR3131 Gene

No Compound Related Data Available

Transcripts for MIR3131 Gene

mRNA/cDNA for MIR3131 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3131 Gene

No ASD Table

Relevant External Links for MIR3131 Gene

GeneLoc Exon Structure for
MIR3131
ECgene alternative splicing isoforms for
MIR3131

Expression for MIR3131 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3131 Gene:

MIR3131
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3131 Gene

Orthologs for MIR3131 Gene

Evolution for MIR3131 Gene

ENSEMBL:
Gene Tree for MIR3131 (if available)
TreeFam:
Gene Tree for MIR3131 (if available)

No data available for Orthologs for MIR3131 Gene

Paralogs for MIR3131 Gene

No data available for Paralogs for MIR3131 Gene

Variants for MIR3131 Gene

Sequence variations from dbSNP and Humsavar for MIR3131 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs121917852 pathogenic, Brachydactyly type A1 219,060,185(-) C/T upstream_transcript_variant
rs121917854 pathogenic, Brachydactyly type A1 219,060,168(-) G/T upstream_transcript_variant
rs121917855 pathogenic, Brachydactyly type A1 219,060,170(-) C/T upstream_transcript_variant
rs121917856 pathogenic, Acrocapitofemoral dysplasia 219,060,331(-) G/A upstream_transcript_variant
rs121917859 pathogenic, Brachydactyly type A1 219,060,184(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3131 Gene

Variant ID Type Subtype PubMed ID
nsv584491 CNV loss 21841781
nsv821902 CNV gain 20364138
nsv954840 CNV deletion 24416366

Additional Variant Information for MIR3131 Gene

Human Gene Mutation Database (HGMD)
MIR3131
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3131

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3131 Gene

Disorders for MIR3131 Gene

Additional Disease Information for MIR3131

No disorders were found for MIR3131 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3131 Gene

Publications for MIR3131 Gene

  1. An indel polymorphism within pre-miR3131 confers risk for hepatocellular carcinoma. (PMID: 28034876) Wang C … Gao Y (Carcinogenesis 2017) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3131 Gene

Sources for MIR3131 Gene

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