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Aliases for MIR30D Gene

Subcategory (RNA class) for MIR30D Gene


Quality Score for this RNA gene is


Aliases for MIR30D Gene

  • MicroRNA 30d 2 3 5
  • Hsa-Mir-30d 3
  • Mir-30d 3
  • MIRN30D 3

External Ids for MIR30D Gene

Previous HGNC Symbols for MIR30D Gene

  • MIRN30D

Previous GeneCards Identifiers for MIR30D Gene

  • GC08M135889

Summaries for MIR30D Gene

Entrez Gene Summary for MIR30D Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30D Gene

MIR30D (MicroRNA 30d) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR30D include Medulloblastoma and Lung Cancer. Among its related pathways are MicroRNAs in cancer and miRNA targets in ECM and membrane receptors.

fRNAdb sequence ontologies for MIR30D Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR30D

Additional gene information for MIR30D Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR30D Gene

Genomics for MIR30D Gene

GeneHancer (GH) Regulatory Elements for MIR30D Gene

Promoters and enhancers for MIR30D Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J134804 Enhancer 0.3 Ensembl 650.7 +0.2 244 0.6 GABPB1 MIR30D GC08P134800 LOC102723694 GC08M134740
GH08J134830 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE 11.2 -27.2 -27166 4.1 CLOCK MLX DMAP1 YY1 SLC30A9 E2F8 ZNF143 SP3 NFYC GLIS1 ENSG00000254028 GC08M134740 LOC102723694 ZFAT ENSG00000259820 MIR30D MIR30B
GH08J134733 Enhancer 1.1 FANTOM5 Ensembl ENCODE 10.3 +70.1 70106 1.8 SIX4 MEIS2 PKNOX1 ESRRA MAX SIN3A FEZF1 ZNF7 CTBP1 GATA3 MIR30B MIR30D ENSG00000272456 ENSG00000278898
GH08J134777 Enhancer 1 FANTOM5 Ensembl ENCODE 11.1 +25.3 25309 4.8 SMARCE1 RFX1 JUN FOSL1 JUND FOS BCL6 FOSL2 TRIM28 MIR30B MIR30D GC08P134784 ENSG00000278898 GC08M134740
GH08J134754 Enhancer 0.9 ENCODE 11 +50.7 50742 0.2 ELF3 FOXA2 ARID4B THRB ZSCAN9 RAD21 RARA YY1 CREM THAP11 MIR30B MIR30D ENSG00000278898 ENSG00000272456 GC08M134740
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR30D on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR30D Gene

Genomic Locations for MIR30D Gene
70 bases
Minus strand
70 bases
Minus strand

Genomic View for MIR30D Gene

Genes around MIR30D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR30D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR30D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30D Gene

ORGUL Member Location for MIR30D Gene

ORGUL Member Location for MIR30D gene

Proteins for MIR30D Gene

Post-translational modifications for MIR30D Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30D Gene

Domains & Families for MIR30D Gene

Gene Families for MIR30D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30D Gene

Function for MIR30D Gene

Phenotypes From GWAS Catalog for MIR30D Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR30D Gene

Localization for MIR30D Gene

Gene Ontology (GO) - Cellular Components for MIR30D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 18766170
genes like me logo Genes that share ontologies with MIR30D: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR30D Gene

Pathways & Interactions for MIR30D Gene

genes like me logo Genes that share pathways with MIR30D: view

Pathways by source for MIR30D Gene

1 BioSystems pathway for MIR30D Gene
1 KEGG pathway for MIR30D Gene

Interacting Proteins for MIR30D Gene

Gene Ontology (GO) - Biological Process for MIR30D Gene


No data available for SIGNOR curated interactions for MIR30D Gene

Drugs & Compounds for MIR30D Gene

No Compound Related Data Available

Transcripts for MIR30D Gene

fRNAdb Secondary structures for MIR30D Gene

  • hsa-mir-30d_MI0000255_Homo_sapiens_miR-30d_stem-loop_hairpin

mRNA/cDNA for MIR30D Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30D Gene

No ASD Table

Relevant External Links for MIR30D Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR30D Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR30D Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR30D Gene

Orthologs for MIR30D Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30D Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-30d 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-30d 34
  • 97 (a)
(Canis familiaris)
Mammalia cfa-mir-30d 34
  • 95 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 85 (a)
(Mus musculus)
Mammalia Mir30d 34
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-30d 34
  • 45 (a)
(Gallus gallus)
Aves gga-mir-30d 34
  • 89 (a)
(Anolis carolinensis)
Reptilia aca-mir-30d 34
  • 63 (a)
(Danio rerio)
Actinopterygii dre-mir-30a 34
  • 67 (a)
Species where no ortholog for MIR30D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30D Gene

Gene Tree for MIR30D (if available)
Gene Tree for MIR30D (if available)

Paralogs for MIR30D Gene

No data available for Paralogs for MIR30D Gene

Variants for MIR30D Gene

Sequence variations from dbSNP and Humsavar for MIR30D Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1003339394 -- 134,805,811(-) A/G upstream_transcript_variant
rs1007378940 -- 134,806,526(-) A/T upstream_transcript_variant
rs1007861639 -- 134,806,263(-) A/G upstream_transcript_variant
rs1008073450 -- 134,805,746(-) G/A upstream_transcript_variant
rs1009123468 -- 134,804,719(-) T/C downstream_transcript_variant

Additional Variant Information for MIR30D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR30D Gene

Disorders for MIR30D Gene

MalaCards: The human disease database

(11) MalaCards diseases for MIR30D Gene - From: miR2Disease

Disorder Aliases PubMed IDs
  • mdb
lung cancer
  • lung cancer, susceptibility to
anaplastic thyroid cancer
  • anaplastic thyroid carcinoma
nonalcoholic fatty liver disease
  • non-alcoholic fatty liver disease
muscular dystrophy, duchenne type
  • dmd
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR30D

genes like me logo Genes that share disorders with MIR30D: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR30D Gene

Publications for MIR30D Gene

  1. Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. (PMID: 28207045) Nijhuis A … Silver A (Human molecular genetics 2017) 3 58
  2. Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis. (PMID: 28651493) Zhang R … Bai J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  3. Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma. (PMID: 28440426) Yan L … Yao J (International journal of molecular medicine 2017) 3 58
  4. Amplification and up-regulation of MIR30D was associated with disease progression of cervical squamous cell carcinomas. (PMID: 28356144) Zhou Y … Fang Z (BMC cancer 2017) 3 58
  5. Circulating miR-30d Predicts Survival in Patients with Acute Heart Failure. (PMID: 28214846) Xiao J … Das S (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 58

Products for MIR30D Gene

Sources for MIR30D Gene

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