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Aliases for MIR30C1 Gene

Subcategory (RNA class) for MIR30C1 Gene


Quality Score for this RNA gene is


Aliases for MIR30C1 Gene

  • MicroRNA 30c-1 2 3 5
  • Hsa-Mir-30c-1 3
  • Mir-30c-1 3
  • MIRN30C1 3
  • MiR-30c 3

External Ids for MIR30C1 Gene

ORGUL Members for MIR30C1 Gene

Previous HGNC Symbols for MIR30C1 Gene

  • MIRN30C1

Previous GeneCards Identifiers for MIR30C1 Gene

  • GC01P040996
  • GC01P041222

Summaries for MIR30C1 Gene

Entrez Gene Summary for MIR30C1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30C1 Gene

MIR30C1 (MicroRNA 30c-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNA targets in ECM and membrane receptors and MicroRNAs in cancer.

Additional gene information for MIR30C1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR30C1 Gene

Genomics for MIR30C1 Gene

GeneHancer (GH) Regulatory Elements for MIR30C1 Gene

Promoters and enhancers for MIR30C1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I040753 Enhancer 0.9 dbSUPER 550.8 -0.9 -893 6.1 FOXA2 MLX ARID4B IRF4 YY1 RUNX3 RXRA JUNB MIER2 REST GC01P040759 GC01P040760 MIR30C1 RIMS3 LOC105378674 ZFP69 KCNQ4 GC01P040755 GC01P040756 MIR30E
GH01I040708 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.2 -46.0 -46046 6.1 PKNOX1 SMAD1 FOXA2 ARNT ARID4B FEZF1 DMAP1 YY1 SLC30A9 POLR2B NFYC EXO5 RLF RIMS3 TRIT1 LOC105378674 NFYC-AS1 MIR30E MIR30C1 LOC105378672
GH01I040690 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 11.1 -64.6 -64583 4.4 ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 SP3 NFYC MEF2D RIMS3 NFYC-AS1 NFYC ENSG00000259943 EXO5 TRIT1 LOC105378674 ZFP69 SLFNL1 MIR30C1
GH01I040698 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.1 -57.7 -57741 2 HDGF ATF1 ZBTB40 BATF IRF4 ZNF121 FOS ATF7 IKZF2 RUNX3 RIMS3 LOC105378674 MIR30E MIR30C1 NFYC ZNF684 KCNQ4 EXO5 CITED4 ZFP69
GH01I040735 Enhancer 1.2 Ensembl ENCODE dbSUPER 12.2 -21.1 -21099 1.3 MEIS2 USF1 ZBTB21 JUN TEAD4 TAL1 MAX CEBPG TCF12 ZNF316 RIMS3 LOC105378674 MIR30C1 NFYC KCNQ4 GC01P040752 NFYC-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR30C1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR30C1 Gene

Genomic Locations for MIR30C1 Gene
89 bases
Plus strand

Genomic View for MIR30C1 Gene

Genes around MIR30C1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR30C1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR30C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30C1 Gene

Proteins for MIR30C1 Gene

Post-translational modifications for MIR30C1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30C1 Gene

Domains & Families for MIR30C1 Gene

Gene Families for MIR30C1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30C1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30C1 Gene

Function for MIR30C1 Gene

Phenotypes From GWAS Catalog for MIR30C1 Gene

Gene Ontology (GO) - Molecular Function for MIR30C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 23749231
genes like me logo Genes that share ontologies with MIR30C1: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR30C1 Gene

Localization for MIR30C1 Gene

Gene Ontology (GO) - Cellular Components for MIR30C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR30C1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR30C1 Gene

Pathways & Interactions for MIR30C1 Gene

genes like me logo Genes that share pathways with MIR30C1: view

Pathways by source for MIR30C1 Gene

1 BioSystems pathway for MIR30C1 Gene
1 KEGG pathway for MIR30C1 Gene

Interacting Proteins for MIR30C1 Gene

Gene Ontology (GO) - Biological Process for MIR30C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010868 negative regulation of triglyceride biosynthetic process IDA 23749231
GO:0035195 gene silencing by miRNA IDA 23749231
GO:0045717 negative regulation of fatty acid biosynthetic process IDA 23749231
GO:0050709 negative regulation of protein secretion IDA 23749231
GO:0071072 negative regulation of phospholipid biosynthetic process IDA 23749231
genes like me logo Genes that share ontologies with MIR30C1: view

No data available for SIGNOR curated interactions for MIR30C1 Gene

Drugs & Compounds for MIR30C1 Gene

No Compound Related Data Available

Transcripts for MIR30C1 Gene

mRNA/cDNA for MIR30C1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30C1 Gene

No ASD Table

Relevant External Links for MIR30C1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR30C1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR30C1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR30C1 Gene:

genes like me logo Genes that share expression patterns with MIR30C1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR30C1 Gene

Orthologs for MIR30C1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30C1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-30c-1 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-30c-1 34
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-30c-2 34
  • 99 (a)
(Mus musculus)
Mammalia Mir30c-1 34
  • 99 (a)
(Bos Taurus)
Mammalia bta-mir-30c 34
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-30c-1 34
  • 82 (a)
(Gallus gallus)
Aves gga-mir-30c-1 34
  • 92 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 85 (a)
(Danio rerio)
Actinopterygii dre-mir-30c 34
  • 70 (a)
Species where no ortholog for MIR30C1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30C1 Gene

Gene Tree for MIR30C1 (if available)
Gene Tree for MIR30C1 (if available)

Paralogs for MIR30C1 Gene

No data available for Paralogs for MIR30C1 Gene

Variants for MIR30C1 Gene

Sequence variations from dbSNP and Humsavar for MIR30C1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001422170 -- 40,755,413(+) C/G upstream_transcript_variant
rs1002599406 -- 40,755,732(+) A/C upstream_transcript_variant
rs1003531088 -- 40,757,660(+) C/T downstream_transcript_variant
rs1003849118 -- 40,757,105(+) A/G upstream_transcript_variant
rs1005706023 -- 40,756,965(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR30C1 Gene

Variant ID Type Subtype PubMed ID
esv3577821 CNV loss 25503493

Additional Variant Information for MIR30C1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR30C1 Gene

Disorders for MIR30C1 Gene

Additional Disease Information for MIR30C1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR30C1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR30C1 Gene

Publications for MIR30C1 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J … Wu X (Molecular carcinogenesis 2010) 3 44 58
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J … Wu X (Carcinogenesis 2010) 3 44 58
  3. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J … Zhao H (International journal of cancer 2009) 3 44 58
  4. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y … Wu X (Cancer prevention research (Philadelphia, Pa.) 2008) 3 44 58
  5. Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression. (PMID: 28423547) Agostini A … Micci F (Oncotarget 2017) 3 58

Products for MIR30C1 Gene

Sources for MIR30C1 Gene

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