microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR30B Gene

Subcategory (RNA class) for MIR30B Gene

miRNA

Number of RNA Genes sources:

5 / 14

Aliases for MIR30B Gene

  • MicroRNA 30b 2 3 5
  • Hsa-MiR-30b-5p 166 177
  • Hsa-MiR-30b-3p 166 177
  • MIMAT0000420 51
  • MIMAT0004589 51
  • Hsa-Mir-30b 3
  • MI0000441 51
  • Mir-30b 3
  • MIRN30B 3
  • RF00131 172
  • MIR30B 2

External Ids for MIR30B Gene

Previous HGNC Symbols for MIR30B Gene

  • MIRN30B

Previous GeneCards Identifiers for MIR30B Gene

  • GC08M135884

Summaries for MIR30B Gene

Entrez Gene Summary for MIR30B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30B Gene

MIR30B (MicroRNA 30b) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR30B include Medulloblastoma and Lymphoma, Hodgkin, Classic. Among its related pathways are MicroRNAs in cancer and miRNA targets in ECM and membrane receptors.

Rfam classification for MIR30B Gene

  • mir-30 microRNA precursor

Additional gene information for MIR30B Gene