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Aliases for MIR3074 Gene

Subcategory (RNA class) for MIR3074 Gene


Quality Score for this RNA gene is


Aliases for MIR3074 Gene

  • MicroRNA 3074 2 3 5
  • Hsa-Mir-3074 3
  • Mir-3074 3

External Ids for MIR3074 Gene

Previous GeneCards Identifiers for MIR3074 Gene

  • GC09U901548
  • GC09M067457
  • GC09M097848

Summaries for MIR3074 Gene

Entrez Gene Summary for MIR3074 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3074 Gene

MIR3074 (MicroRNA 3074) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cell Differentiation - Index and miRNAs involved in DNA damage response.

fRNAdb sequence ontologies for MIR3074 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR3074

Additional gene information for MIR3074 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3074 Gene

Genomics for MIR3074 Gene

GeneHancer (GH) Regulatory Elements for MIR3074 Gene

Promoters and enhancers for MIR3074 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J095084 Enhancer 0.4 ENCODE dbSUPER 650.7 +0.3 265 2 GC09P095099 GC09P095100 GC09P095102 GC09P095103 GC09P095104 MIR23B MIR24-1 MIR27B MIR3074 C9orf3
GH09J095016 Enhancer 1.4 Ensembl ENCODE dbSUPER 12.2 +64.2 64247 10.7 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 YY1 FOS NFYC REST KAT8 MIR23B MIR27B MIR3074 C9orf3 MIR6081 LOC101928119
GH09J095053 Enhancer 1.1 Ensembl ENCODE dbSUPER 12.6 +29.2 29222 6.2 JUN MAX FEZF1 ZIC2 HIC1 ZNF335 ZFHX2 ZNF213 POLR2A PRDM10 MIR23B MIR27B MIR3074 MIR6081 LOC101928119 C9orf3
GH09J095060 Enhancer 1 ENCODE dbSUPER 13.7 +22.1 22127 6 FOXA2 ARID4B RAD21 RARA YY1 EGR1 CREM THAP11 RXRA SP5 MIR6081 MIR23B MIR27B MIR3074 C9orf3 LOC101928119
GH09J095106 Enhancer 0.6 ENCODE dbSUPER 12.7 -21.5 -21526 2.3 ZNF316 MAFK PIR48893 MIR23B MIR27B MIR3074 PIR51992 FANCC C9orf3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3074 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3074 Gene

Genomic Locations for MIR3074 Gene
81 bases
Minus strand
81 bases
Minus strand

Genomic View for MIR3074 Gene

Genes around MIR3074 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3074 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3074 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3074 Gene

ORGUL Member Location for MIR3074 Gene

ORGUL Member Location for MIR3074 gene

Proteins for MIR3074 Gene

Post-translational modifications for MIR3074 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3074 Gene

Domains & Families for MIR3074 Gene

Gene Families for MIR3074 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3074: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3074 Gene

Function for MIR3074 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3074 Gene

Localization for MIR3074 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3074 Gene

Pathways & Interactions for MIR3074 Gene

No data available for SIGNOR curated interactions for MIR3074 Gene

Drugs & Compounds for MIR3074 Gene

No Compound Related Data Available

Transcripts for MIR3074 Gene

fRNAdb Secondary structures for MIR3074 Gene

  • hsa-miR-3074-5p_MIMAT0019208_Homo_sapiens_miR-3074-5p_mature

mRNA/cDNA for MIR3074 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3074 Gene

No ASD Table

Relevant External Links for MIR3074 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR3074 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3074 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3074 Gene:

genes like me logo Genes that share expression patterns with MIR3074: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3074 Gene

Orthologs for MIR3074 Gene

Evolution for MIR3074 Gene

Gene Tree for MIR3074 (if available)
Gene Tree for MIR3074 (if available)

No data available for Orthologs for MIR3074 Gene

Paralogs for MIR3074 Gene

No data available for Paralogs for MIR3074 Gene

Variants for MIR3074 Gene

Sequence variations from dbSNP and Humsavar for MIR3074 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000887918 -- 95,086,259(-) T/C upstream_transcript_variant
rs1001174130 -- 95,087,437(-) T/C upstream_transcript_variant
rs1001236818 -- 95,086,454(-) C/T upstream_transcript_variant
rs1001623597 -- 95,087,250(-) C/T upstream_transcript_variant
rs1006024541 -- 95,085,625(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3074 Gene

Variant ID Type Subtype PubMed ID
nsv1038106 CNV gain 25217958
nsv1147999 OTHER inversion 26484159
nsv831656 CNV loss 17160897

Additional Variant Information for MIR3074 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3074 Gene

Disorders for MIR3074 Gene

Additional Disease Information for MIR3074

No disorders were found for MIR3074 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3074 Gene

Publications for MIR3074 Gene

  1. High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. (PMID: 27835701) Navarro-Quiroz E … Aroca G (PloS one 2016) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3074 Gene

Sources for MIR3074 Gene

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