microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3065 Gene

Data sources for MIR3065 Gene:

RNA type for MIR3065 Gene

miRNA

Aliases for MIR3065 Gene

External Ids for MIR3065 Gene

Previous GeneCards Identifiers for MIR3065 Gene

  • GC17U901491
  • GC17P074538
  • GC17P079099

Summaries for MIR3065 Gene

Entrez Gene Summary for MIR3065 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3065 Gene

MIR3065 (MicroRNA 3065) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR3065 include Coach Syndrome 1.

Rfam classification for MIR3065 Gene

Additional gene information for MIR3065 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR3065 Gene

Genomics for MIR3065 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3065 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J081126 Promoter/Enhancer 0.7 Ensembl dbSUPER 250.7 -0.6 -576 0.6 KLF1 HIC1 MIR3065 MIR338 lnc-CEP131-1 MIR657 AATK BAIAP2 SLC38A10 lnc-CEP131-2 PVALEF lnc-TMEM105-1
GH17J081127 Enhancer 0.4 Ensembl dbSUPER 250.7 +1.3 1324 0.4 ZNF600 MIR3065 MIR338 lnc-CEP131-2 MIR657 SLC38A10 AATK PVALEF BAIAP2 lnc-TMEM105-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3065 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3065 Gene

Latest Assembly
chr17:81,125,877-81,125,955
(GRCh38/hg38)
Size:
79 bases
Orientation:
Plus strand

Previous Assembly
chr17:79,099,677-79,099,755
(GRCh37/hg19 by Entrez Gene)
Size:
79 bases
Orientation:
Plus strand

chr17:79,099,677-79,099,755
(GRCh37/hg19 by Ensembl)
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR3065 Gene

Genes around MIR3065 on UCSC Golden Path with GeneCards custom track
MIR3065 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3065 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3065 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3065 Gene

Proteins for MIR3065 Gene

Post-translational modifications for MIR3065 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3065 Gene

Domains & Families for MIR3065 Gene

Gene Families for MIR3065 Gene

HGNC:
genes like me logo Genes that share domains with MIR3065: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3065 Gene

Function for MIR3065 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3065 Gene

Localization for MIR3065 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3065 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3065 Gene

Pathways & Interactions for MIR3065 Gene

PathCards logo

SuperPathways for MIR3065 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR3065 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR3065: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR3065 Gene

Drugs & Compounds for MIR3065 Gene

No Compound Related Data Available

Transcripts for MIR3065 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3065 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000029D793_9606 miRNA 23 6

RefSeq: NR_036151,

LncBase: hsa-miR-3065-3p,

miRBase: MIMAT0015378,

MirGeneDB: Hsa-Mir-338-P1-as_3p,

TarBase: hsa-miR-3065-3p,

ENA: LM381806.1:1..23:ncRNA, LM611041.1:50..72:ncRNA,

URS00003FB16B_9606 miRNA 23 5

RefSeq: NR_036151,

LncBase: hsa-miR-3065-5p,

miRBase: MIMAT0015066,

TarBase: hsa-miR-3065-5p,

ENA: FR772706.1:1..23:ncRNA, LM381679.1:1..23:ncRNA, LM611041.1:10..32:ncRNA,

URS000075E912_9606 pre_miRNA 79 4

RefSeq: NR_036151,

Ensembl: ENST00000390137 (view in UCSC) ,

miRBase: MI0014228,

ENA: LM611041.1:1..79:precursor_RNA,

URS0000EFC794_9606 pre_miRNA 64 1

MirGeneDB: Hsa-Mir-338-P1-as,

URS0000EFB9F2_9606 miRNA 25 1

MirGeneDB: Hsa-Mir-338-P1-as_5p,

MIR3065 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR3065 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3065 Gene

No ASD Table

Relevant External Links for MIR3065 Gene

GeneLoc Exon Structure for
MIR3065

Expression for MIR3065 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3065 Gene

Orthologs for MIR3065 Gene

Evolution for MIR3065 Gene

ENSEMBL:
Gene Tree for MIR3065 (if available)
TreeFam:
Gene Tree for MIR3065 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3065

No data available for Orthologs for MIR3065 Gene

Paralogs for MIR3065 Gene

No data available for Paralogs for MIR3065 Gene

Variants for MIR3065 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3065 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR3065 Gene

Variant ID Type Subtype PubMed ID
dgv3292n100 CNV gain 25217958
esv26223 CNV gain+loss 19812545
nsv1065052 CNV gain 25217958
nsv1066947 CNV loss 25217958
nsv470619 CNV loss 18288195
nsv523417 CNV gain 19592680
nsv828128 CNV loss 20364138
nsv833564 CNV loss 17160897
nsv952388 CNV deletion 24416366

Additional Variant Information for MIR3065 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3065
Leiden Open Variation Database (LOVD)
MIR3065

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR3065 Gene

Disorders for MIR3065 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR3065 Gene - From: COP

Disorder Aliases PubMed IDs
coach syndrome 1
  • coach1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR3065

genes like me logo Genes that share disorders with MIR3065: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR3065 Gene

Publications for MIR3065 Gene

  1. A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. (PMID: 29871690) Bensen JT … Olshan AF (Breast cancer research : BCR 2018) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3
  5. Discovery of microRNAs and other small RNAs in solid tumors. (PMID: 20483914) Meiri E … Sitbon E (Nucleic acids research 2010) 3

Products for MIR3065 Gene

Sources for MIR3065 Gene