microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR3064 Gene

Data sources for MIR3064 Gene:

RNA type for MIR3064 Gene

miRNA

Aliases for MIR3064 Gene

External Ids for MIR3064 Gene

Previous GeneCards Identifiers for MIR3064 Gene

  • GC17U901653
  • GC17M062502

Summaries for MIR3064 Gene

Entrez Gene Summary for MIR3064 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3064 Gene

MIR3064 (MicroRNA 3064) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are mRNA Splicing - Major Pathway and Circadian rythm related genes.

Additional gene information for MIR3064 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR3064 Gene

Genomics for MIR3064 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR3064 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J064499 Enhancer 0.5 ENCODE 250.7 +0.8 831 0.2 ZNF600 POLR2A RBM22 PRDM10 BMI1 BACH1 POLR2B CHD1 HSALNG0118098 HSALNG0118099 MIR3064 MIR5047 MK280245 MK280246 POLG2 DDX5 CEP95
GH17J064501 Enhancer 0.3 ENCODE 250.7 +0.3 251 0.2 SMAD5 POLR2A HSALNG0118099 MIR3064 MIR5047 MK280245 MK280246 LRRC37A3 POLG2 DDX5 CEP95
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR3064 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR3064 Gene

Latest Assembly
chr17:64,500,774-64,500,839
(GRCh38/hg38)
Size:
66 bases
Orientation:
Minus strand

Previous Assembly
chr17:62,496,892-62,496,957
(GRCh37/hg19 by Entrez Gene)
Size:
66 bases
Orientation:
Minus strand

Genomic View for MIR3064 Gene

Genes around MIR3064 on UCSC Golden Path with GeneCards custom track
MIR3064 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR3064 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3064 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3064 Gene

Proteins for MIR3064 Gene

Post-translational modifications for MIR3064 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3064 Gene

Domains & Families for MIR3064 Gene

Gene Families for MIR3064 Gene

HGNC:
genes like me logo Genes that share domains with MIR3064: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR3064 Gene

Function for MIR3064 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3064 Gene

Localization for MIR3064 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR3064 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3064 Gene

Pathways & Interactions for MIR3064 Gene

genes like me logo Genes that share pathways with MIR3064: view

Pathways by source for MIR3064 Gene

Gene Ontology (GO) - Biological Process for MIR3064 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR3064 Gene

Drugs & Compounds for MIR3064 Gene

No Compound Related Data Available

Transcripts for MIR3064 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR3064 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000021ECD0_9606 miRNA 21 5

RefSeq: NR_039891,

LncBase: hsa-miR-3064-5p,

miRBase: MIMAT0019864,

TarBase: hsa-miR-3064-5p,

ENA: FR772704.1:1..21:ncRNA,

URS000075BCCE_9606 precursor_RNA 66 3

RefSeq: NR_039891,

Ensembl: ENST00000581130 (view in UCSC) ,

miRBase: MI0017375,

URS0000047615_9606 miRNA 23 3

RefSeq: NR_039891,

miRBase: MIMAT0019865,

ENA: FR772703.1:1..23:ncRNA,

MIR3064 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3064 Gene

No ASD Table

Relevant External Links for MIR3064 Gene

GeneLoc Exon Structure for
MIR3064

No data available for mRNA/cDNA for MIR3064 Gene

Expression for MIR3064 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3064 Gene

genes like me logo Genes that share expression patterns with MIR3064: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3064 Gene

Orthologs for MIR3064 Gene

Evolution for MIR3064 Gene

ENSEMBL:
Gene Tree for MIR3064 (if available)
TreeFam:
Gene Tree for MIR3064 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR3064

No data available for Orthologs for MIR3064 Gene

Paralogs for MIR3064 Gene

No data available for Paralogs for MIR3064 Gene

Variants for MIR3064 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR3064 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for MIR3064 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3064
Leiden Open Variation Database (LOVD)
MIR3064

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3064 Gene

Disorders for MIR3064 Gene

Additional Disease Information for MIR3064

No disorders were found for MIR3064 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3064 Gene

Publications for MIR3064 Gene

  1. MicroRNA-3064-5p sponged by MALAT1 suppresses angiogenesis in human hepatocellular carcinoma by targeting the FOXA1/CD24/Src pathway. (PMID: 31914639) Zhang P … Liu C (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020) 3
  2. Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression. (PMID: 31488171) Yan J … Zhou X (Journal of experimental & clinical cancer research : CR 2019) 3
  3. MicroRNA-532 and microRNA-3064 inhibit cell proliferation and invasion by acting as direct regulators of human telomerase reverse transcriptase in ovarian cancer. (PMID: 28291810) Bai L … Bai J (PloS one 2017) 3
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR3064 Gene

Sources for MIR3064 Gene