microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR302F Gene

Data sources for MIR302F Gene:

Subcategory (RNA class) for MIR302F Gene

miRNA

Aliases for MIR302F Gene

External Ids for MIR302F Gene

Previous HGNC Symbols for MIR302F Gene

  • MIRN302F

Previous GeneCards Identifiers for MIR302F Gene

  • GC00U922975
  • GC18P026132
  • GC18P027878

Summaries for MIR302F Gene

Entrez Gene Summary for MIR302F Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR302F Gene

MIR302F (MicroRNA 302f) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR302F include Astigmatism and Congenital Generalized Lipodystrophy.

Additional gene information for MIR302F Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR302F Gene

Genomics for MIR302F Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR302F Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J030308 Enhancer 0.2 Ensembl 0.4 +10.0 9991 0.2 MIR302F LOC105372046 ENSG00000286605 DSC3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR302F on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR302F Gene

Latest Assembly
chr18:30,298,910-30,298,960
(GRCh38/hg38)
Size:
51 bases
Orientation:
Plus strand

Previous Assembly
chr18:27,878,876-27,878,926
(GRCh37/hg19 by Entrez Gene)
Size:
51 bases
Orientation:
Plus strand

Genomic View for MIR302F Gene

Genes around MIR302F on UCSC Golden Path with GeneCards custom track
MIR302F in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR302F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR302F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR302F Gene

Proteins for MIR302F Gene

Post-translational modifications for MIR302F Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR302F Gene

Domains & Families for MIR302F Gene

Gene Families for MIR302F Gene

genes like me logo Genes that share domains with MIR302F: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR302F Gene

Function for MIR302F Gene

Phenotypes From GWAS Catalog for MIR302F Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR302F Gene

Localization for MIR302F Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR302F Gene

Pathways & Interactions for MIR302F Gene

PathCards logo

SuperPathways for MIR302F Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR302F Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR302F Gene

Drugs & Compounds for MIR302F Gene

No Compound Related Data Available

Transcripts for MIR302F Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR302F Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C007_9606 precursor_RNA 51 3

RefSeq: NR_031684,

Ensembl: ENST00000635955 (view in UCSC) ,

miRBase: MI0006418,

URS000075D4BB_9606 miRNA 17 2

RefSeq: NR_031684,

miRBase: MIMAT0005932,

MIR302F in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR302F Gene

No ASD Table

Relevant External Links for MIR302F Gene

GeneLoc Exon Structure for
MIR302F

No data available for mRNA/cDNA for MIR302F Gene

Expression for MIR302F Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR302F

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR302F Gene

Orthologs for MIR302F Gene

Evolution for MIR302F Gene

ENSEMBL:
Gene Tree for MIR302F (if available)
TreeFam:
Gene Tree for MIR302F (if available)

No data available for Orthologs for MIR302F Gene

Paralogs for MIR302F Gene

No data available for Paralogs for MIR302F Gene

Variants for MIR302F Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR302F Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR302F Gene

Variant ID Type Subtype PubMed ID
nsv1057946 CNV gain 25217958
nsv576600 CNV loss 21841781
nsv576626 CNV loss 21841781

Additional Variant Information for MIR302F Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR302F

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR302F Gene

Disorders for MIR302F Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR302F Gene - From: COP and GCD

Disorder Aliases PubMed IDs
astigmatism
congenital generalized lipodystrophy
  • beradinelli-seip syndrome
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR302F

genes like me logo Genes that share disorders with MIR302F: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR302F Gene

Publications for MIR302F Gene

  1. Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout. (PMID: 31289104) Kawamura Y … Matsuo H (Annals of the rheumatic diseases 2019) 3
  2. Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways. (PMID: 27637763) Hagen EM … Mills JL (Human genetics 2016) 3
  3. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. (PMID: 25367360) Li Q … CREAM Consortium (Human genetics 2015) 3
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR302F Gene

Sources for MIR302F Gene