microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR302E Gene

Subcategory (RNA class) for MIR302E Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR302E Gene

  • MicroRNA 302e 2 3 5
  • Hsa-Mir-302e 2 3
  • MIR302E 2 5
  • MIMAT0005931 50
  • Hsa-MiR-302e 173
  • MI0006417 50
  • MIRN302E 3

External Ids for MIR302E Gene

Previous HGNC Symbols for MIR302E Gene

  • MIRN302E

Previous GeneCards Identifiers for MIR302E Gene

  • GC00U923166
  • GC11P007213
  • GC11P007255

Summaries for MIR302E Gene

Entrez Gene Summary for MIR302E Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR302E Gene

MIR302E (MicroRNA 302e) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cell Differentiation - Index.

Additional gene information for MIR302E Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR302E Gene

Genomics for MIR302E Gene

Genomic Locations for MIR302E Gene

Genomic Locations for MIR302E Gene
chr11:7,234,766-7,234,837
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand
chr11:7,255,997-7,256,068
(GRCh37/hg19)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR302E Gene

Genes around MIR302E on UCSC Golden Path with GeneCards custom track
MIR302E in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR302E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR302E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR302E Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR302E Gene

Proteins for MIR302E Gene

Post-translational modifications for MIR302E Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR302E Gene

Domains & Families for MIR302E Gene

Gene Families for MIR302E Gene

HGNC:
genes like me logo Genes that share domains with MIR302E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR302E Gene

Function for MIR302E Gene

Phenotypes From GWAS Catalog for MIR302E Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR302E Gene

Localization for MIR302E Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR302E gene
Compartment Confidence
cytoskeleton 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR302E Gene

Pathways & Interactions for MIR302E Gene

PathCards logo

SuperPathways for MIR302E Gene

SuperPathway Contained pathways
1 Cell Differentiation - Index
genes like me logo Genes that share pathways with MIR302E: view

Pathways by source for MIR302E Gene

1 BioSystems pathway for MIR302E Gene

Gene Ontology (GO) - Biological Process for MIR302E Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR302E Gene

Drugs & Compounds for MIR302E Gene

No Compound Related Data Available

Transcripts for MIR302E Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR302E Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B201_9606 precursor_RNA 72 4

HGNC: 35348,

RefSeq: NR_031683,

Ensembl: ENST00000408776 (view in UCSC) ,

miRBase: MI0006417,

URS000075E566_9606 miRNA 17 3

RefSeq: NR_031683,

miRBase: MIMAT0005931,

TarBase: hsa-miR-302e,

MIR302E in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR302E Gene

No ASD Table

Relevant External Links for MIR302E Gene

GeneLoc Exon Structure for
MIR302E

No data available for mRNA/cDNA for MIR302E Gene

Expression for MIR302E Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR302E

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR302E Gene

Orthologs for MIR302E Gene

Evolution for MIR302E Gene

ENSEMBL:
Gene Tree for MIR302E (if available)
TreeFam:
Gene Tree for MIR302E (if available)

No data available for Orthologs for MIR302E Gene

Paralogs for MIR302E Gene

No data available for Paralogs for MIR302E Gene

Variants for MIR302E Gene

Additional dbSNP identifiers (rs#s) for MIR302E Gene

Additional Variant Information for MIR302E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR302E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR302E Gene

Disorders for MIR302E Gene

Additional Disease Information for MIR302E

No disorders were found for MIR302E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR302E Gene

Publications for MIR302E Gene

  1. Long noncoding RNA FGD5-AS1 promotes colorectal cancer cell proliferation, migration, and invasion through upregulating CDCA7 via sponging miR-302e. (PMID: 31332696) Li D … Chen Z (In vitro cellular & developmental biology. Animal 2019) 3
  2. MiR-302e attenuates allergic inflammation in vitro model by targeting RelA. (PMID: 29748238) Xiao L … Li Y (Bioscience reports 2018) 3
  3. Sevoflurane‑induced neurotoxicity is driven by OXR1 post‑transcriptional downregulation involving hsa‑miR‑302e. (PMID: 30221705) Yang L … Peng J (Molecular medicine reports 2018) 3
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR302E Gene

Sources for MIR302E Gene