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Aliases for MIR301A Gene

Subcategory (RNA class) for MIR301A Gene


Quality Score for this RNA gene is


Aliases for MIR301A Gene

  • MicroRNA 301a 2 3 5
  • MicroRNA 301 2 3
  • Hsa-Mir-301a 3
  • Hsa-Mir-301 3
  • Mir-301a 3
  • MIRN301A 3
  • MIRN301 3
  • MIR301 3

External Ids for MIR301A Gene

Previous HGNC Symbols for MIR301A Gene

  • MIRN301
  • MIRN301A

Previous GeneCards Identifiers for MIR301A Gene

  • GC17M054587
  • GC17M057228

Summaries for MIR301A Gene

Entrez Gene Summary for MIR301A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR301A Gene

MIR301A (MicroRNA 301a) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR301A Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR301A

Additional gene information for MIR301A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR301A Gene

Genomics for MIR301A Gene

GeneHancer (GH) Regulatory Elements for MIR301A Gene

Promoters and enhancers for MIR301A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I059148 Enhancer 0.6 ENCODE 550.8 +1.6 1631 2.3 MZF1 ZBTB8A SP1 ZNF664 ZNF316 JUND ZKSCAN8 FOS FOSL2 GC17P059152 GC17M059152 MIR301A RAD51C TRIM37 GC17M059142 SKA2
GH17I059110 Enhancer 0.5 dbSUPER 11.6 +39.2 39189 2.7 PKNOX1 ZNF362 PRDM6 ZNF157 ZNF384 TRIM37 MIR301A MIR454 SKA2 PRR11 GC17M059110 ENSG00000224738
GH17I059046 Enhancer 0.5 ENCODE 11 +104.8 104796 0.1 FOSL1 ATF1 GABPB1 ATF7 EP300 CREM MIR301A SMG8 MTMR4 GC17P059054 GC17M059024 TRIM37
GH17I059123 Enhancer 0.4 FANTOM5 12.2 +28.0 28019 0.1 ZNF121 ZNF362 GC17M059121 MIR301A PRR11 SKA2 SMG8 GDPD1 RNU2-58P
GH17I059121 Enhancer 0.3 dbSUPER 12.2 +29.1 29078 0.6 ZNF362 GC17M059121 MIR301A PRR11 SKA2 SMG8 RNU2-58P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR301A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR301A Gene

Genomic Locations for MIR301A Gene
86 bases
Minus strand

Genomic View for MIR301A Gene

Genes around MIR301A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR301A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR301A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR301A Gene

ORGUL Member Location for MIR301A Gene

ORGUL Member Location for MIR301A gene

Proteins for MIR301A Gene

Post-translational modifications for MIR301A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR301A Gene

Domains & Families for MIR301A Gene

Gene Families for MIR301A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR301A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR301A Gene

Function for MIR301A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR301A Gene

Localization for MIR301A Gene

Gene Ontology (GO) - Cellular Components for MIR301A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 25203061
genes like me logo Genes that share ontologies with MIR301A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR301A Gene

Pathways & Interactions for MIR301A Gene

SuperPathways for MIR301A Gene

No Data Available

Interacting Proteins for MIR301A Gene

Gene Ontology (GO) - Biological Process for MIR301A Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR301A Gene

Drugs & Compounds for MIR301A Gene

No Compound Related Data Available

Transcripts for MIR301A Gene

fRNAdb Secondary structures for MIR301A Gene

  • hsa-miR-301a-5p_MIMAT0022696_Homo_sapiens_miR-301a-5p_mature
  • hsa-mir-301a_MI0000745_Homo_sapiens_miR-301a_stem-loop_hairpin

mRNA/cDNA for MIR301A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR301A Gene

No ASD Table

Relevant External Links for MIR301A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR301A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR301A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR301A Gene:

genes like me logo Genes that share expression patterns with MIR301A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR301A Gene

Orthologs for MIR301A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR301A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-301a 34
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-301a 34
  • 100 (a)
(Monodelphis domestica)
Mammalia mdo-mir-301 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-301a 34
  • 100 (a)
(Mus musculus)
Mammalia Mir301 34
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-301 34
  • 64 (a)
(Gallus gallus)
Aves gga-mir-301b 34
  • 89 (a)
(Anolis carolinensis)
Reptilia aca-mir-301a 34
  • 83 (a)
(Danio rerio)
Actinopterygii dre-mir-301a 34
  • 79 (a)
dre-mir-130a 34
  • 51 (a)
Species where no ortholog for MIR301A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR301A Gene

Gene Tree for MIR301A (if available)
Gene Tree for MIR301A (if available)

Paralogs for MIR301A Gene

No data available for Paralogs for MIR301A Gene

Variants for MIR301A Gene

Sequence variations from dbSNP and Humsavar for MIR301A Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1001565228 -- 59,151,970(-) T/G upstream_transcript_variant
rs1001994806 -- 59,151,584(-) A/G upstream_transcript_variant
rs1005672495 -- 59,152,789(-) T/C upstream_transcript_variant
rs1007392127 -- 59,150,934(-) A/C downstream_transcript_variant
rs1009932346 -- 59,152,957(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR301A Gene

Variant ID Type Subtype PubMed ID
dgv3270n100 CNV gain 25217958
dgv3271n100 CNV gain 25217958
esv2758699 CNV gain 17122850
esv3573764 CNV gain 25503493
nsv1065063 CNV gain 25217958
nsv575802 CNV loss 21841781
nsv833499 CNV loss 17160897

Additional Variant Information for MIR301A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR301A Gene

Disorders for MIR301A Gene

Additional Disease Information for MIR301A

No disorders were found for MIR301A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR301A Gene

Publications for MIR301A Gene

  1. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber MJ (The FEBS journal 2005) 1 3 58
  2. Human embryonic stem cells express a unique set of microRNAs. (PMID: 15183728) Suh MR … Kim KS (Developmental biology 2004) 1 3 58
  3. Embryonic stem cell-specific MicroRNAs. (PMID: 12919684) Houbaviy HB … Sharp PA (Developmental cell 2003) 1 3 58
  4. The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection. (PMID: 28196914) Hazra B … Basu A (Science signaling 2017) 3 58
  5. MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1. (PMID: 28193514) He C … Liu Z (Gastroenterology 2017) 3 58

Products for MIR301A Gene

Sources for MIR301A Gene

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