Aliases for MIR29C Gene
Subcategory (RNA class) for MIR29C Gene
miRNA
Quality Score for this RNA gene is
10.2
External Ids for MIR29C Gene
- HGNC: 31621
- Entrez Gene: 407026
- Ensembl: ENSG00000284214
- OMIM: 610784
- miRBase: hsa-mir-29c
ORGUL Members for MIR29C Gene
Previous HGNC Symbols for MIR29C Gene
- MIRN29C
Previous GeneCards Identifiers for MIR29C Gene
- GC01M206043
- GC01M207975
Summaries for MIR29C Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR29C Gene
MIR29C (MicroRNA 29c) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR29C include Progesterone Resistance. Among its related pathways are MicroRNAs in cancer and Metastatic brain tumor.
fRNAdb sequence ontologies for MIR29C Gene - the ORGUL cluster for this gene includes several descriptions:
-
pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.
-
nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.
Additional gene information for MIR29C Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR29C Gene
Genomics for MIR29C Gene
GeneHancer (GH) Regulatory Elements for MIR29C Gene
Promoters and enhancers for MIR29C Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01I207796 | Enhancer | 1 | Ensembl ENCODE | 0.8 | +4.4 | 4406 | 1.1 | ATF1 PKNOX1 ARNT BATF RAD21 RFX5 POLR2B ZNF143 FOS CREM | CR1L MIR29C CDCA4P4 MIR29B2CHG | |
| GH01I207799 | Enhancer | 0.4 | ENCODE | 0.8 | +2.8 | 2808 | 0.2 | POLR2A CBFB RUNX3 | MIR29C CDCA4P4 MIR29B2CHG | |
| GH01I207798 | Enhancer | 0.4 | Ensembl | 0.8 | +3.0 | 3038 | 0.2 | POLR2A CBFB | CD46 MIR29C CDCA4P4 MIR29B2CHG | |
| GH01I207789 | Enhancer | 0.6 | ENCODE | 0.4 | +11.3 | 11318 | 2.6 | SMARCE1 HLF DPF2 ATF2 GATA3 CTBP1 ATF7 PRDM1 TCF7L2 | CR1L MIR29C CDCA4P4 CD46 MIR29B2CHG |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MIR29C on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MIR29C Gene
Genomic Locations for MIR29C Gene
- chr1:207,801,852-207,801,939
- (GRCh38/hg38)
- Size:
- 88 bases
- Orientation:
- Minus strand
- chr1:207,974,863-208,042,495
- (GRCh37/hg19)
Genomic View for MIR29C Gene
Genes around MIR29C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q32.2 by Ensembl
- 1q32.2 by Entrez Gene
- 1q32.2 by HGNC
MIR29C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR29C Gene
ORGUL Member Location for MIR29C Gene
Proteins for MIR29C Gene
Post-translational modifications for MIR29C Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR29C
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR29C
- Origene Custom Protein Services for MIR29C
- Search GeneTex for Proteins for MIR29C
No data available for DME Specific Peptides for MIR29C Gene
Domains & Families for MIR29C Gene
Gene Families for MIR29C Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR29C Gene
Function for MIR29C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:1903231 | mRNA binding involved in posttranscriptional gene silencing | IDA | 18390668 |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR29C
-
- Search ViGene Biosciences for MIR29C
CRISPR Products
- Browse CRISPR knockouts for MIR29C
- Applied Biological Materials CRISPR for MIR29C
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR29C
Inhibitory RNA Products
- Search ViGene Biosciences for MIR29C
Clone Products
- GenScript: Custom all cDNA clones Services for MIR29C
- VectorBuilder custom plasmid, inducible vectors for MIR29C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR29C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR29C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR29C Gene
Localization for MIR29C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IDA | 26646931 |
| GO:0005622 | intracellular | IEA | -- |
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0070062 | extracellular exosome | IDA | 28159509 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR29C Gene
Pathways & Interactions for MIR29C Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | MicroRNAs in cancer | ||
| 2 | Metastatic brain tumor | ||
Pathways by source for MIR29C Gene
1 BioSystems pathway for MIR29C Gene
1 KEGG pathway for MIR29C Gene
Interacting Proteins for MIR29C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001953 | negative regulation of cell-matrix adhesion | IDA | 23936390 |
| GO:0008285 | negative regulation of cell proliferation | IDA | 20086245 |
| GO:0010629 | negative regulation of gene expression | IDA | 20570858 |
| GO:0016525 | negative regulation of angiogenesis | IDA | 26175848 |
| GO:0030336 | negative regulation of cell migration | IDA | 23936390 |
No data available for SIGNOR curated interactions for MIR29C Gene
Transcripts for MIR29C Gene
fRNAdb Secondary structures for MIR29C Gene
mRNA/cDNA for MIR29C Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR29C
- Applied Biological Materials CRISPR for MIR29C
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR29C
Inhibitory RNA Products
- Search ViGene Biosciences for MIR29C
Clone Products
- GenScript: Custom all cDNA clones Services for MIR29C
- VectorBuilder custom plasmid, inducible vectors for MIR29C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR29C
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR29C
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR29C Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR29C Gene:
MIR29CPrimer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR29C Gene
Orthologs for MIR29C Gene
No data available for Orthologs for MIR29C Gene
Paralogs for MIR29C Gene
No data available for Paralogs for MIR29C Gene
Variants for MIR29C Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000416979 | -- | 207,802,346(-) | G/A | upstream_transcript_variant | |
| rs1001828775 | -- | 207,802,550(-) | G/A | upstream_transcript_variant | |
| rs1001861430 | -- | 207,801,386(-) | T/A | downstream_transcript_variant | |
| rs1003668706 | -- | 207,802,574(-) | T/G | upstream_transcript_variant | |
| rs1004693670 | -- | 207,803,930(-) | GGGGG/GGGGGG | upstream_transcript_variant |
Additional Variant Information for MIR29C Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR29C
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR29C Gene
Disorders for MIR29C Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| progesterone resistance |
|
|
Search MIR29C in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MIR29C
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MIR29C Gene
Publications for MIR29C Gene
- Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. (PMID: 28159509) Beltrami C … Emanueli C (Molecular therapy : the journal of the American Society of Gene Therapy 2017) 3 58
- Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle. (PMID: 28404597) Massart J … Krook A (Diabetes 2017) 3 58
- WITHDRAWN: Circular RNA hsa_circ_0001564 facilitates tumorigenesis of osteosarcoma via sponging miR-29c-3p. (PMID: 28789596) (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
- miR-29a/b/c function as invasion suppressors for gliomas by targeting CDC42 and predict the prognosis of patients. (PMID: 28787434) Shi C … Yu S (British journal of cancer 2017) 3 58
- Circulating miRNA29 family expression levels in patients with essential hypertension as potential markers for left ventricular hypertrophy. (PMID: 28287884) Huang Y … Feng Y (Clinical and experimental hypertension (New York, N.Y. : 1993) 2017) 3 58
Products for MIR29C Gene
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- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Custom all cDNA clones Services for MIR29C
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR29C
- VectorBuilder custom plasmid, inducible vectors for MIR29C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR29C
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR29C
- Search GeneTex for Proteins for MIR29C
Sources for MIR29C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew