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Aliases for MIR2392 Gene

Subcategory (RNA class) for MIR2392 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR2392 Gene

  • MicroRNA 2392 2 3 5
  • Hsa-Mir-2392 3

External Ids for MIR2392 Gene

Previous GeneCards Identifiers for MIR2392 Gene

  • GC14U901278
  • GC14P101282
  • GC14P101212
  • GC14P101794
  • GC14P102087
  • GC14P102321
  • GC14P102492
  • GC14P102666
  • GC14P102839
  • GC14P103012

Summaries for MIR2392 Gene

Entrez Gene Summary for MIR2392 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2392 Gene

MIR2392 (MicroRNA 2392) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR2392 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR2392 Gene

Genomics for MIR2392 Gene

GeneHancer (GH) Regulatory Elements for MIR2392 Gene

Promoters and enhancers for MIR2392 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J100815 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 650.7 +1.6 1572 1.8 FOXA2 MLX ARID4B DMAP1 ZNF48 ETS1 SLC30A9 NFKBIZ RXRA SP5 ENSG00000275161 MIR2392 ENSG00000274884 MEG3
GH14J100788 Enhancer 1.1 ENCODE dbSUPER 0.3 -23.8 -23754 5.5 ATF1 TCF12 GATA2 ATF7 NCOA1 REST ZNF592 MBD2 NFIL3 ATF4 DLK1 MIR493 MIR337 MIR127 MIR136 MIR431 MIR433 RTL1 BEGAIN MEG3
GH14J100801 Enhancer 0.7 ENCODE dbSUPER 0.4 -11.4 -11354 3.1 SCRT1 ZFP69B ZFHX2 ZNF692 SCRT2 CEBPG MIR2392 MEG3
GH14J100796 Enhancer 0.6 ENCODE dbSUPER 0.4 -17.3 -17323 0.8 ZBTB33 MAFK MEG3 MIR2392
GH14J100782 Enhancer 0.8 ENCODE dbSUPER 0.3 -29.4 -29443 5.6 GATAD2A TFAP4 FOXA2 FOXA3 ATF2 RAD21 ZNF205 GATA3 RCOR1 PRDM10 DLK1 MEG3 MIR2392
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR2392 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR2392 Gene

Genomic Locations for MIR2392 Gene
chr14:100,814,491-100,814,574
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand
chr14:101,280,828-101,280,911
(GRCh37/hg19)
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR2392 Gene

Genes around MIR2392 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2392 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2392 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2392 Gene

Proteins for MIR2392 Gene

Post-translational modifications for MIR2392 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2392 Gene

Domains & Families for MIR2392 Gene

Gene Families for MIR2392 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR2392: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR2392 Gene

Function for MIR2392 Gene

Phenotypes From GWAS Catalog for MIR2392 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2392 Gene

Localization for MIR2392 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR2392 Gene

Pathways & Interactions for MIR2392 Gene

SuperPathways for MIR2392 Gene

No Data Available

Interacting Proteins for MIR2392 Gene

Gene Ontology (GO) - Biological Process for MIR2392 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR2392 Gene

Drugs & Compounds for MIR2392 Gene

No Compound Related Data Available

Transcripts for MIR2392 Gene

mRNA/cDNA for MIR2392 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2392 Gene

No ASD Table

Relevant External Links for MIR2392 Gene

GeneLoc Exon Structure for
MIR2392
ECgene alternative splicing isoforms for
MIR2392

Expression for MIR2392 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR2392 Gene:

MIR2392
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2392 Gene

Orthologs for MIR2392 Gene

Evolution for MIR2392 Gene

ENSEMBL:
Gene Tree for MIR2392 (if available)
TreeFam:
Gene Tree for MIR2392 (if available)

No data available for Orthologs for MIR2392 Gene

Paralogs for MIR2392 Gene

No data available for Paralogs for MIR2392 Gene

Variants for MIR2392 Gene

Sequence variations from dbSNP and Humsavar for MIR2392 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000117210 -- 100,813,586(+) G/T upstream_transcript_variant
rs1001242230 -- 100,813,869(+) G/A upstream_transcript_variant
rs1001286082 -- 100,813,082(+) G/A upstream_transcript_variant
rs1004692975 -- 100,812,982(+) G/A upstream_transcript_variant
rs1007557507 -- 100,814,805(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR2392 Gene

Variant ID Type Subtype PubMed ID
nsv832876 CNV loss 17160897
nsv483116 CNV gain 15286789
nsv470669 CNV loss 18288195
nsv1041097 CNV gain 25217958
esv3635516 CNV gain 21293372
esv2751158 CNV gain 17911159

Additional Variant Information for MIR2392 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2392

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR2392 Gene

Disorders for MIR2392 Gene

Additional Disease Information for MIR2392

No disorders were found for MIR2392 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2392 Gene

Publications for MIR2392 Gene

  1. MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. (PMID: 28512191) Li J … Fan D (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR2392 Gene

Sources for MIR2392 Gene

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