microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR2392 Gene

Subcategory (RNA class) for MIR2392 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR2392 Gene

  • MicroRNA 2392 2 3 5
  • Hsa-Mir-2392 2 3
  • MIR2392 2 5
  • MIMAT0019043 50
  • MI0016870 50

External Ids for MIR2392 Gene

Previous GeneCards Identifiers for MIR2392 Gene

  • GC14U901278
  • GC14P101282
  • GC14P101212
  • GC14P101794
  • GC14P103603
  • GC14P103820
  • GC14P104080
  • GC14P104439
  • GC14P102087
  • GC14P102321
  • GC14P102492
  • GC14P102666
  • GC14P102839
  • GC14P103012
  • GC14P103211
  • GC14P103421

Summaries for MIR2392 Gene

Entrez Gene Summary for MIR2392 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2392 Gene

MIR2392 (MicroRNA 2392) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR2392 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR2392 Gene

Genomics for MIR2392 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR2392 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J100801 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -10.8 -10787 4.2 CEBPG HNRNPL ZNF692 SCRT2 SCRT1 ZFHX2 ZFP69B RPL26P4 lnc-DLK1-14 MIR2392 MEG3 DLK1 RTL1
GH14J100808 Enhancer 0.6 dbSUPER 0.4 -6.1 -6121 0.7 CBX3 ZSCAN29 XRCC3 TRIM28 TRIM24 CBX5 CBX1 GLIS1 ZEB2 ZBTB33 MIR2392 lnc-DLK1-14 MEG3 DLK1 RTL1
GH14J100800 Enhancer 0.3 Ensembl 0.4 -14.1 -14090 0.4 PRDM10 lnc-DLK1-14 MIR2392 MEG3 DLK1 RTL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR2392 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR2392 Gene

Genomic Locations for MIR2392 Gene
chr14:100,814,491-100,814,574
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand
chr14:101,280,828-101,280,911
(GRCh37/hg19)
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR2392 Gene

Genes around MIR2392 on UCSC Golden Path with GeneCards custom track
MIR2392 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR2392 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2392 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2392 Gene

Proteins for MIR2392 Gene

Post-translational modifications for MIR2392 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2392 Gene

Domains & Families for MIR2392 Gene

Gene Families for MIR2392 Gene

HGNC:
genes like me logo Genes that share domains with MIR2392: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR2392 Gene

Function for MIR2392 Gene

Phenotypes From GWAS Catalog for MIR2392 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2392 Gene

Localization for MIR2392 Gene

Gene Ontology (GO) - Cellular Components for MIR2392 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903561 extracellular vesicle HDA 28798470
genes like me logo Genes that share ontologies with MIR2392: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR2392 Gene

Pathways & Interactions for MIR2392 Gene

PathCards logo

SuperPathways for MIR2392 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR2392 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR2392 Gene

Drugs & Compounds for MIR2392 Gene

No Compound Related Data Available

Transcripts for MIR2392 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR2392 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000759E16_9606 precursor_RNA 84 4

HGNC: 41843,

RefSeq: NR_039729,

Ensembl: ENST00000584881 (view in UCSC) ,

miRBase: MI0016870,

URS00003F7488_9606 miRNA 20 2

RefSeq: NR_039729,

miRBase: MIMAT0019043,

MIR2392 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2392 Gene

No ASD Table

Relevant External Links for MIR2392 Gene

GeneLoc Exon Structure for
MIR2392

No data available for mRNA/cDNA for MIR2392 Gene

Expression for MIR2392 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2392 Gene

Orthologs for MIR2392 Gene

Evolution for MIR2392 Gene

ENSEMBL:
Gene Tree for MIR2392 (if available)
TreeFam:
Gene Tree for MIR2392 (if available)

No data available for Orthologs for MIR2392 Gene

Paralogs for MIR2392 Gene

No data available for Paralogs for MIR2392 Gene

Variants for MIR2392 Gene

Additional dbSNP identifiers (rs#s) for MIR2392 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR2392 Gene

Variant ID Type Subtype PubMed ID
esv2751158 CNV gain 17911159
esv3635516 CNV gain 21293372
nsv1041097 CNV gain 25217958
nsv470669 CNV loss 18288195
nsv483116 CNV gain 15286789
nsv832876 CNV loss 17160897

Additional Variant Information for MIR2392 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2392

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR2392 Gene

Disorders for MIR2392 Gene

Additional Disease Information for MIR2392

No disorders were found for MIR2392 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2392 Gene

Publications for MIR2392 Gene

  1. LncRNA CACNA1G-AS1 facilitates hepatocellular carcinoma progression through the miR-2392/C1orf61 pathway. (PMID: 30908634) Yang J … E C (Journal of cellular physiology 2019) 3
  2. Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs. (PMID: 28798470) Enomoto Y … Miyajima A (Scientific reports 2017) 3
  3. MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. (PMID: 28512191) Li J … Fan D (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017) 3
  4. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR2392 Gene

Sources for MIR2392 Gene