microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR2355 Gene

Subcategory (RNA class) for MIR2355 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR2355 Gene

  • MicroRNA 2355 2 3 5
  • Hsa-MiR-2355-3p 166 177
  • Hsa-MiR-2355-5p 166 177
  • Hsa-Mir-2355 3
  • MIMAT0017950 51
  • MIMAT0016895 51
  • MI0015873 51
  • Mir-2355 3
  • MIR2355 2

External Ids for MIR2355 Gene

Previous GeneCards Identifiers for MIR2355 Gene

  • GC02U902217
  • GC02M199824
  • GC02M207975

Summaries for MIR2355 Gene

Entrez Gene Summary for MIR2355 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR2355 Gene

MIR2355 (MicroRNA 2355) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR2355 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR2355 Gene

Genomics for MIR2355 Gene

GeneHancer (GH) Regulatory Elements for MIR2355 Gene

Promoters and enhancers for MIR2355 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J207140 Promoter/Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.1 -32.9 -32903 4.7 ZIC2 TRIM28 CTCF RAD21 OSR2 NR2F2 ZNF384 ZKSCAN1 POLR2A REST KLF7 MIR2355 MIR1302-4 CREB1 METTL21A KLF7-IT1 MYOSLID lnc-MDH1B-8
GH02J207131 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 11.6 -24.3 -24253 6.5 EP300 JUND TRIM28 ATF2 OSR2 KDM1A BCL11A KLF9 WT1 NFIC MIR2355 KLF7 KLF7-IT1 MYOSLID lnc-MDH1B-8
GH02J207237 Promoter/Enhancer 1.2 Ensembl ENCODE dbSUPER 10.5 -130.0 -129965 4.9 JUND FOS REST POLR2A ZNF316 SRF FOSL2 SPI1 NFE2 FOSL1 MIR1302-4 KLF7 ENSG00000240440 MIR2355 ENSG00000225916 ENSG00000234902 MYOSLID-AS1 MYOSLID ENSG00000223725
GH02J207151 Enhancer 1.2 FANTOM5 ENCODE dbSUPER 10.4 -43.9 -43916 5.9 EP300 JUND RELA ZBTB17 ZNF384 GATA3 TFDP1 POLR2A ZBTB33 SPI1 MIR2355 MIR1302-4 KLF7 CREB1 MYOSLID lnc-MDH1B-8 KLF7-IT1
GH02J207073 Enhancer 1 UCNEbase ENCODE dbSUPER 11.6 +35.7 35709 2 CTCF POLR2A ZNF335 RAD21 BCL3 FOXA1 RUNX3 SCRT2 KLF7 MIR2355 piR-47018 HSALNG0021846 lnc-MDH1B-8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR2355 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR2355 Gene

Genomic Locations for MIR2355 Gene
chr2:207,109,987-207,110,073
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand
chr2:207,974,711-207,974,797
(GRCh37/hg19)
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR2355 Gene

Genes around MIR2355 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR2355 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR2355 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR2355 Gene

Proteins for MIR2355 Gene

Post-translational modifications for MIR2355 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR2355 Gene

Domains & Families for MIR2355 Gene

Gene Families for MIR2355 Gene

HGNC:
genes like me logo Genes that share domains with MIR2355: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR2355 Gene

Function for MIR2355 Gene

Phenotypes From GWAS Catalog for MIR2355 Gene

Gene Ontology (GO) - Molecular Function for MIR2355 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 28122380
genes like me logo Genes that share ontologies with MIR2355: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR2355 Gene

Localization for MIR2355 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR2355 Gene

Pathways & Interactions for MIR2355 Gene

PathCards logo

SuperPathways for MIR2355 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR2355 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 28122380
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IDA 28122380
GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IDA 28122380
genes like me logo Genes that share ontologies with MIR2355: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR2355 Gene

Drugs & Compounds for MIR2355 Gene

No Compound Related Data Available

Transcripts for MIR2355 Gene

mRNA/cDNA for MIR2355 Gene

5 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
7 ENA transcripts :
2 LncBase transcripts :
2 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR2355 Gene

No ASD Table

Relevant External Links for MIR2355 Gene

GeneLoc Exon Structure for
MIR2355

Expression for MIR2355 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR2355 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR2355

genes like me logo Genes that share expression patterns with MIR2355: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR2355 Gene

Orthologs for MIR2355 Gene

Evolution for MIR2355 Gene

ENSEMBL:
Gene Tree for MIR2355 (if available)
TreeFam:
Gene Tree for MIR2355 (if available)

No data available for Orthologs for MIR2355 Gene

Paralogs for MIR2355 Gene

No data available for Paralogs for MIR2355 Gene

Variants for MIR2355 Gene

Additional dbSNP identifiers (rs#s) for MIR2355 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR2355 Gene

Variant ID Type Subtype PubMed ID
nsv1138887 CNV deletion 24896259
nsv3129 CNV deletion 18451855

Additional Variant Information for MIR2355 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR2355

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR2355 Gene

Disorders for MIR2355 Gene

Additional Disease Information for MIR2355

No disorders were found for MIR2355 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR2355 Gene

Publications for MIR2355 Gene

  1. ERRFI1 Inhibits Proliferation and Inflammation of Nucleus Pulposus and Is Negatively Regulated by miR-2355-5p in Intervertebral Disc Degeneration. (PMID: 30817728) Guo Y … Shen Y (Spine 2019) 3 54
  2. Dysregulation of Vascular Endothelial Growth Factor Receptor-2 by Multiple miRNAs in Endothelial Colony-Forming Cells of Coronary Artery Disease. (PMID: 28122380) Su SH … Wang HW (Journal of vascular research 2017) 3 54
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 54
  4. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 54
  5. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 54

Products for MIR2355 Gene

Sources for MIR2355 Gene