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Aliases for MIR219B Gene

Subcategory (RNA class) for MIR219B Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR219B Gene

  • MicroRNA 219b 2 3 5
  • MicroRNA 2964a 2 3
  • Hsa-Mir-2964a 3
  • Hsa-Mir-219b 3
  • Mir-219b 3
  • MIR2964A 3

External Ids for MIR219B Gene

ORGUL Members for MIR219B Gene

Previous HGNC Symbols for MIR219B Gene

  • MIR2964A

Previous GeneCards Identifiers for MIR219B Gene

  • GC09P131158

Summaries for MIR219B Gene

Entrez Gene Summary for MIR219B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR219B Gene

MIR219B (MicroRNA 219b) is an RNA Gene, and is affiliated with the undefined RNA class.

Additional gene information for MIR219B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR219B Gene

Genomics for MIR219B Gene

GeneHancer (GH) Regulatory Elements for MIR219B Gene

Promoters and enhancers for MIR219B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I128393 Enhancer 0.6 dbSUPER 550.8 +2.0 1966 1.8 ZBTB6 GLIS1 CBFA2T3 REST FOS ZBTB8A KDM1A EZH2 GC09M128394 MIR219A2 MIR219B DNM1 CERCAM
GH09I128398 Enhancer 0.6 ENCODE dbSUPER 550.8 +0.8 766 0 POLR2A SUZ12 EZH2 ENSG00000272593 GC09M128394 MIR219A2 MIR219B CERCAM
GH09I128391 Enhancer 0.4 dbSUPER 550.8 -1.0 -967 0.4 POLR2A EZH2 ENSG00000272593 GC09M128394 MIR219A2 MIR219B URM1
GH09I128394 Enhancer 0.4 dbSUPER 550.8 -0.6 -613 0.2 SUZ12 EZH2 ENSG00000272593 GC09M128394 MIR219A2 MIR219B URM1
GH09I128395 Enhancer 0.4 dbSUPER 550.8 +0.3 259 0.2 SUZ12 EZH2 ENSG00000272593 GC09M128394 MIR219A2 MIR219B CERCAM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR219B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR219B Gene

Genomic Locations for MIR219B Gene
chr9:128,392,621-128,392,708
(GRCh38/hg38)
Size:
88 bases
Orientation:
Plus strand
chr9:131,154,900-131,154,987
(GRCh37/hg19)

Genomic View for MIR219B Gene

Genes around MIR219B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR219B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR219B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR219B Gene

Proteins for MIR219B Gene

Post-translational modifications for MIR219B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR219B Gene

Domains & Families for MIR219B Gene

Gene Families for MIR219B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR219B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR219B Gene

Function for MIR219B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR219B Gene

Localization for MIR219B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR219B Gene

Pathways & Interactions for MIR219B Gene

SuperPathways for MIR219B Gene

No Data Available

Interacting Proteins for MIR219B Gene

Gene Ontology (GO) - Biological Process for MIR219B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR219B Gene

Drugs & Compounds for MIR219B Gene

No Compound Related Data Available

Transcripts for MIR219B Gene

mRNA/cDNA for MIR219B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR219B Gene

No ASD Table

Relevant External Links for MIR219B Gene

GeneLoc Exon Structure for
MIR219B
ECgene alternative splicing isoforms for
MIR219B

Expression for MIR219B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR219B Gene:

MIR219B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR219B Gene

Orthologs for MIR219B Gene

Evolution for MIR219B Gene

ENSEMBL:
Gene Tree for MIR219B (if available)
TreeFam:
Gene Tree for MIR219B (if available)

No data available for Orthologs for MIR219B Gene

Paralogs for MIR219B Gene

No data available for Paralogs for MIR219B Gene

Variants for MIR219B Gene

Sequence variations from dbSNP and Humsavar for MIR219B Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000157282 -- 128,393,007(+) C/G downstream_transcript_variant
rs1001192432 -- 128,391,110(+) A/G upstream_transcript_variant
rs1003115895 -- 128,390,784(+) C/G upstream_transcript_variant
rs1004051074 -- 128,392,622(+) G/A non_coding_transcript_variant
rs1004103312 -- 128,392,367(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR219B Gene

Variant ID Type Subtype PubMed ID
nsv831728 CNV loss 17160897

Additional Variant Information for MIR219B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR219B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR219B Gene

Disorders for MIR219B Gene

Additional Disease Information for MIR219B

No disorders were found for MIR219B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR219B Gene

Publications for MIR219B Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR219B Gene

Sources for MIR219B Gene

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