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Aliases for MIR20B Gene

Subcategory (RNA class) for MIR20B Gene


Quality Score for this RNA gene is


Aliases for MIR20B Gene

  • MicroRNA 20b 2 3 5
  • Hsa-Mir-20b 3
  • Mir-20b 3
  • MIRN20B 3

External Ids for MIR20B Gene

Previous HGNC Symbols for MIR20B Gene

  • MIRN20B

Previous GeneCards Identifiers for MIR20B Gene

  • GC0XM133153
  • GC0XM133160
  • GC0XM133307
  • GC0XM133312
  • GC0XM133316
  • GC0XM133320
  • GC0XM133325
  • GC0XM133329
  • GC0XM133333
  • GC0XM133337
  • GC0XM133340
  • GC0XM133351
  • GC0XM133375
  • GC0XM134173
  • GC0XM134178
  • GC0XM134183
  • GC0XM134190
  • GC0XM134196

Summaries for MIR20B Gene

Entrez Gene Summary for MIR20B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR20B Gene

MIR20B (MicroRNA 20b) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway.

Additional gene information for MIR20B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR20B Gene

Genomics for MIR20B Gene

Genomic Locations for MIR20B Gene

Genomic Locations for MIR20B Gene
69 bases
Minus strand

Genomic View for MIR20B Gene

Genes around MIR20B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR20B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR20B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR20B Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR20B Gene

Proteins for MIR20B Gene

Post-translational modifications for MIR20B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR20B Gene

Domains & Families for MIR20B Gene

Gene Families for MIR20B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR20B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR20B Gene

Function for MIR20B Gene

Gene Ontology (GO) - Molecular Function for MIR20B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 20190813
genes like me logo Genes that share ontologies with MIR20B: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR20B Gene

Localization for MIR20B Gene

Gene Ontology (GO) - Cellular Components for MIR20B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR20B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR20B Gene

Pathways & Interactions for MIR20B Gene

SuperPathways for MIR20B Gene

SuperPathway Contained pathways
1 Parkinsons Disease Pathway
genes like me logo Genes that share pathways with MIR20B: view

Pathways by source for MIR20B Gene

1 BioSystems pathway for MIR20B Gene

Interacting Proteins for MIR20B Gene

Gene Ontology (GO) - Biological Process for MIR20B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 20190813
GO:0071356 cellular response to tumor necrosis factor IDA 28595801
GO:1905563 negative regulation of vascular endothelial cell proliferation IMP 28595801
GO:2000774 positive regulation of cellular senescence IMP 28595801
genes like me logo Genes that share ontologies with MIR20B: view

No data available for SIGNOR curated interactions for MIR20B Gene

Drugs & Compounds for MIR20B Gene

No Compound Related Data Available

Transcripts for MIR20B Gene

mRNA/cDNA for MIR20B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR20B Gene

No ASD Table

Relevant External Links for MIR20B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR20B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR20B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR20B Gene

Orthologs for MIR20B Gene

Evolution for MIR20B Gene

Gene Tree for MIR20B (if available)
Gene Tree for MIR20B (if available)

No data available for Orthologs for MIR20B Gene

Paralogs for MIR20B Gene

No data available for Paralogs for MIR20B Gene

Variants for MIR20B Gene

Sequence variations from dbSNP and Humsavar for MIR20B Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1003822325 -- 134,171,007(-) T/C upstream_transcript_variant
rs1004871742 -- 134,171,563(-) A/G upstream_transcript_variant
rs1004902717 -- 134,170,953(-) A/G upstream_transcript_variant
rs1005828091 -- 134,169,983(-) T/G upstream_transcript_variant
rs1007316405 -- 134,171,110(-) G/A upstream_transcript_variant

Additional Variant Information for MIR20B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR20B Gene

Disorders for MIR20B Gene

Additional Disease Information for MIR20B

No disorders were found for MIR20B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR20B Gene

Publications for MIR20B Gene

  1. miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer. (PMID: 27878272) Fu Q … Xie J (Oncology reports 2017) 3 58
  2. MiR-20b inhibits mycobacterium tuberculosis induced inflammation in the lung of mice through targeting NLRP3. (PMID: 28606793) Lou J … Qiu W (Experimental cell research 2017) 3 58
  3. Deregulation of hsa-miR-20b expression in TNF-α-induced premature senescence of human pulmonary microvascular endothelial cells. (PMID: 28595801) Wong PF … Abubakar S (Microvascular research 2017) 3 58
  4. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  5. MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1/FIP200 in breast cancer cells. (PMID: 26829385) Li S … Chen B (Life sciences 2016) 3 58

Products for MIR20B Gene

Sources for MIR20B Gene

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