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Aliases for MIR20A Gene

Subcategory (RNA class) for MIR20A Gene

undefined

Quality Score for this RNA gene is

3

Aliases for MIR20A Gene

  • MicroRNA 20a 2 3 5
  • Putative MicroRNA 17 Host Gene Protein 3
  • Putative MicroRNA Host Gene 1 Protein 3
  • MicroRNA 20 2
  • Hsa-Mir-20a 3
  • Hsa-Mir-20 3
  • C13orf25 3
  • MiRNA20A 3
  • MIR17HG 3
  • Mir-20a 3
  • MIRN20A 3
  • MIRHG1 3
  • MiR-20 3
  • MIRN20 3
  • MIRH1 3
  • MIR20 3

External Ids for MIR20A Gene

ORGUL Members for MIR20A Gene

Previous HGNC Symbols for MIR20A Gene

  • MIRN20
  • MIRN20A

Previous GeneCards Identifiers for MIR20A Gene

  • GC13P090872
  • GC13P090880
  • GC13P092016
  • GC13P092024
  • GC13P092031
  • GC13P092039
  • GC13P092048
  • GC13P092058
  • GC13P092067
  • GC13P092077
  • GC13P092086
  • GC13P092001
  • GC13P091353
  • GC13P091358
  • GC13P091364
  • GC13P091375
  • GC13P091382

Summaries for MIR20A Gene

Entrez Gene Summary for MIR20A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR20A Gene

MIR20A (MicroRNA 20a) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are DNA Damage Response and MicroRNAs in cancer.

Additional gene information for MIR20A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR20A Gene

Genomics for MIR20A Gene

GeneHancer (GH) Regulatory Elements for MIR20A Gene

Promoters and enhancers for MIR20A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I091346 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 0.8 -2.0 -2032 4.8 PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 GLIS2 GC13P091372 GC13P091377 GC13P091384 GC13P091391 GC13P091394 GC13P091397 GC13P091399 GC13P091400 GC13P091401 MIR17
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR20A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR20A Gene

Genomic Locations for MIR20A Gene
chr13:91,351,065-91,351,135
(GRCh38/hg38)
Size:
71 bases
Orientation:
Plus strand
chr13:92,000,074-92,006,833
(GRCh37/hg19)

Genomic View for MIR20A Gene

Genes around MIR20A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR20A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR20A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR20A Gene

Proteins for MIR20A Gene

Post-translational modifications for MIR20A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR20A Gene

Domains & Families for MIR20A Gene

Gene Families for MIR20A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR20A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR20A Gene

Function for MIR20A Gene

Gene Ontology (GO) - Molecular Function for MIR20A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000993 RNA polymerase II core binding IDA 25336585
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IMP 19390056
genes like me logo Genes that share ontologies with MIR20A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR20A Gene

Localization for MIR20A Gene

Gene Ontology (GO) - Cellular Components for MIR20A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR20A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR20A Gene

Pathways & Interactions for MIR20A Gene

genes like me logo Genes that share pathways with MIR20A: view

Pathways by source for MIR20A Gene

1 KEGG pathway for MIR20A Gene

Interacting Proteins for MIR20A Gene

Gene Ontology (GO) - Biological Process for MIR20A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003151 outflow tract morphogenesis ISS --
GO:0010611 NOT regulation of cardiac muscle hypertrophy ISS --
GO:0010629 negative regulation of gene expression IMP 22450430
GO:0010667 negative regulation of cardiac muscle cell apoptotic process ISS --
GO:0030514 negative regulation of BMP signaling pathway IGI 22450430
genes like me logo Genes that share ontologies with MIR20A: view

No data available for SIGNOR curated interactions for MIR20A Gene

Drugs & Compounds for MIR20A Gene

No Compound Related Data Available

Transcripts for MIR20A Gene

mRNA/cDNA for MIR20A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR20A Gene

No ASD Table

Relevant External Links for MIR20A Gene

GeneLoc Exon Structure for
MIR20A
ECgene alternative splicing isoforms for
MIR20A

Expression for MIR20A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR20A Gene:

MIR20A
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR20A Gene

Orthologs for MIR20A Gene

Evolution for MIR20A Gene

ENSEMBL:
Gene Tree for MIR20A (if available)
TreeFam:
Gene Tree for MIR20A (if available)

No data available for Orthologs for MIR20A Gene

Paralogs for MIR20A Gene

No data available for Paralogs for MIR20A Gene

Variants for MIR20A Gene

Sequence variations from dbSNP and Humsavar for MIR20A Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1001980789 -- 91,351,489(+) G/A downstream_transcript_variant
rs1002349918 -- 91,351,188(+) T/C/G downstream_transcript_variant
rs1002944928 -- 91,349,535(+) G/A upstream_transcript_variant
rs1003385207 -- 91,349,835(+) A/G upstream_transcript_variant
rs1004372915 -- 91,349,113(+) C/G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR20A Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV gain 17160897

Additional Variant Information for MIR20A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR20A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR20A Gene

Disorders for MIR20A Gene

Additional Disease Information for MIR20A

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR20A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR20A Gene

Publications for MIR20A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J … Zhao H (BMC cancer 2010) 3 44 58
  2. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J … Zhao H (International journal of cancer 2009) 3 44 58
  3. Human Argonaute3 has slicer activity. (PMID: 29040713) Park MS … Nakanishi K (Nucleic acids research 2017) 3 58
  4. Establishment of twist-1 and TGFBR2 as direct targets of microRNA-20a in mesenchymal to epithelial transition of breast cancer cell-line MDA-MB-231. (PMID: 28987542) De S … Sengupta Bandyopadhyay S (Experimental cell research 2017) 3 58
  5. MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability. (PMID: 28628113) Liu L … Xu N (Oncogene 2017) 3 58

Products for MIR20A Gene

Sources for MIR20A Gene

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