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Aliases for MIR19B2 Gene

Subcategory (RNA class) for MIR19B2 Gene


Quality Score for this RNA gene is


Aliases for MIR19B2 Gene

  • MicroRNA 19b-2 2 3 5
  • Hsa-Mir-19b-2 3
  • MiR-19b-2 3
  • MIRN19B2 3

External Ids for MIR19B2 Gene

Previous HGNC Symbols for MIR19B2 Gene

  • MIRN19B2

Previous GeneCards Identifiers for MIR19B2 Gene

  • GC0XM133152
  • GC0XM133159
  • GC0XM133306
  • GC0XM133311
  • GC0XM133315
  • GC0XM133319
  • GC0XM133324
  • GC0XM133328
  • GC0XM133332
  • GC0XM133336
  • GC0XM133338
  • GC0XM133349
  • GC0XM133373
  • GC0XM134172
  • GC0XM134177
  • GC0XM134182
  • GC0XM134189
  • GC0XM134195

Summaries for MIR19B2 Gene

Entrez Gene Summary for MIR19B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR19B2 Gene

MIR19B2 (MicroRNA 19b-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Parkinsons Disease Pathway.

Additional gene information for MIR19B2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR19B2 Gene

Genomics for MIR19B2 Gene

Genomic Locations for MIR19B2 Gene

Genomic Locations for MIR19B2 Gene
96 bases
Minus strand

Genomic View for MIR19B2 Gene

Genes around MIR19B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR19B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR19B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR19B2 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR19B2 Gene

Proteins for MIR19B2 Gene

Post-translational modifications for MIR19B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR19B2 Gene

Domains & Families for MIR19B2 Gene

Gene Families for MIR19B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR19B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR19B2 Gene

Function for MIR19B2 Gene

Gene Ontology (GO) - Molecular Function for MIR19B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 18728182
genes like me logo Genes that share ontologies with MIR19B2: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR19B2 Gene

Localization for MIR19B2 Gene

Gene Ontology (GO) - Cellular Components for MIR19B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
GO:0048471 perinuclear region of cytoplasm ISS --
GO:0072562 blood microparticle IDA 24998411
genes like me logo Genes that share ontologies with MIR19B2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR19B2 Gene

Pathways & Interactions for MIR19B2 Gene

genes like me logo Genes that share pathways with MIR19B2: view

Pathways by source for MIR19B2 Gene

1 BioSystems pathway for MIR19B2 Gene
1 KEGG pathway for MIR19B2 Gene

Interacting Proteins for MIR19B2 Gene

Gene Ontology (GO) - Biological Process for MIR19B2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008284 positive regulation of cell proliferation ISS --
GO:0010629 negative regulation of gene expression IDA 25765596
GO:0010667 negative regulation of cardiac muscle cell apoptotic process ISS --
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle IDA 22197821
GO:0035195 gene silencing by miRNA IDA 18728182
genes like me logo Genes that share ontologies with MIR19B2: view

No data available for SIGNOR curated interactions for MIR19B2 Gene

Drugs & Compounds for MIR19B2 Gene

No Compound Related Data Available

Transcripts for MIR19B2 Gene

mRNA/cDNA for MIR19B2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR19B2 Gene

No ASD Table

Relevant External Links for MIR19B2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR19B2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR19B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR19B2 Gene:

genes like me logo Genes that share expression patterns with MIR19B2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR19B2 Gene

Orthologs for MIR19B2 Gene

Evolution for MIR19B2 Gene

Gene Tree for MIR19B2 (if available)
Gene Tree for MIR19B2 (if available)

No data available for Orthologs for MIR19B2 Gene

Paralogs for MIR19B2 Gene

No data available for Paralogs for MIR19B2 Gene

Variants for MIR19B2 Gene

Sequence variations from dbSNP and Humsavar for MIR19B2 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1003822325 -- 134,171,007(-) T/C upstream_transcript_variant
rs1004871742 -- 134,171,563(-) A/G upstream_transcript_variant
rs1004902717 -- 134,170,953(-) A/G upstream_transcript_variant
rs1005828091 -- 134,169,983(-) T/G upstream_transcript_variant
rs1007316405 -- 134,171,110(-) G/A upstream_transcript_variant

Additional Variant Information for MIR19B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR19B2 Gene

Disorders for MIR19B2 Gene

Additional Disease Information for MIR19B2

No disorders were found for MIR19B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR19B2 Gene

Publications for MIR19B2 Gene

  1. Mitochondria-targeted esculetin inhibits PAI-1 levels by modulating STAT3 activation and miR-19b via SIRT3: Role in acute coronary artery syndrome. (PMID: 28213977) Katta S … Kotamraju S (Journal of cellular physiology 2018) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1. (PMID: 25765596) Lv YC … Tang CK (Atherosclerosis 2015) 3 58
  4. The miR-19a/b family positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1. (PMID: 24117217) Song DW … Kim DH (The Biochemical journal 2014) 3 58
  5. MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. (PMID: 24998411) Li S … Chen H (Journal of molecular and cellular cardiology 2014) 3 58

Products for MIR19B2 Gene

Sources for MIR19B2 Gene

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