Aliases for MIR1915HG Gene

RNA type for MIR1915HG Gene

lncRNA

Aliases for MIR1915HG Gene

External Ids for MIR1915HG Gene

Previous HGNC Symbols for MIR1915HG Gene

  • C10orf114
  • CASC10

Summaries for MIR1915HG Gene

GeneCards Summary for MIR1915HG Gene

MIR1915HG (MIR1915 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR1915HG include Prostate Rhabdomyosarcoma and Prostate Sarcoma.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1915HG Gene

Genomics for MIR1915HG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1915HG Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1915HG on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MIR1915HG

Genomic Locations for MIR1915HG Gene

Latest Assembly
chr10:21,492,657-21,497,260
(GRCh38/hg38)
Size:
4,604 bases
Orientation:
Minus strand

Previous Assembly
chr10:21,781,587-21,786,189
(GRCh37/hg19 by Entrez Gene)
Size:
4,603 bases
Orientation:
Minus strand

chr10:21,781,587-21,786,191
(GRCh37/hg19 by Ensembl)
Size:
4,605 bases
Orientation:
Minus strand

Genomic View for MIR1915HG Gene

Genes around MIR1915HG on UCSC Golden Path with GeneCards custom track
MIR1915HG in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1915HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1915HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1915HG Gene

Proteins for MIR1915HG Gene

  • Protein details for MIR1915HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T4H9-CSC10_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR1915-HG
    Protein Accession:
    Q5T4H9
    Secondary Accessions:
    • A1L4M3

    Protein attributes for MIR1915HG Gene

    Size:
    136 amino acids
    Molecular mass:
    14851 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MIR1915HG Gene

Post-translational modifications for MIR1915HG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MIR1915HG Gene

Domains & Families for MIR1915HG Gene

Gene Families for MIR1915HG Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
genes like me logo Genes that share domains with MIR1915HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1915HG Gene

Function for MIR1915HG Gene

Phenotypes From GWAS Catalog for MIR1915HG Gene

Phenotypes for MIR1915HG Gene

genes like me logo Genes that share phenotypes with MIR1915HG: view

CRISPR products for research

miRNA for MIR1915HG Gene

miRTarBase miRNAs that target MIR1915HG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR1915HG Gene

Localization for MIR1915HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1915HG gene
Compartment Confidence
extracellular 2
plasma membrane 1
nucleus 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MIR1915HG Gene

Pathways & Interactions for MIR1915HG Gene

PathCards logo

SuperPathways for MIR1915HG Gene

No Data Available

Interacting Proteins for MIR1915HG Gene

Selected Interacting proteins: Q5T4H9-CSC10_HUMAN for MIR1915HG Gene via IID

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for MIR1915HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1915HG Gene

Drugs & Compounds for MIR1915HG Gene

No Compound Related Data Available

Transcripts for MIR1915HG Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1915HG Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000E60A5A_9606 lncRNA 3799 2

RefSeq: NR_160800,

Ensembl: ENST00000658000 (view in UCSC) ,

URS00008B628A_9606 lncRNA 1020 2

LNCipedia: lnc-CASC10-3:1,

NONCODE: NONHSAT011709.2,

MIR1915HG in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1915HG Gene

1 REFSEQ mRNAs :
4 NCBI additional mRNA sequence :

CRISPR products for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MIR1915HG

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1915HG Gene

No ASD Table

Relevant External Links for MIR1915HG Gene

GeneLoc Exon Structure for
MIR1915HG

Expression for MIR1915HG Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1915HG

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1915HG Gene

Orthologs for MIR1915HG Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1915HG Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CASC10 29 30
  • 99.51 (n)
OneToOne
Species where no ortholog for MIR1915HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR1915HG Gene

ENSEMBL:
Gene Tree for MIR1915HG (if available)
TreeFam:
Gene Tree for MIR1915HG (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MIR1915HG: view image
Alliance of Genome Resources:
Additional Orthologs for MIR1915HG

Paralogs for MIR1915HG Gene

No data available for Paralogs for MIR1915HG Gene

Variants for MIR1915HG Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR1915HG Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
rs11012724 -- p.Arg73Pro

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1915HG Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1915HG Gene

Variant ID Type Subtype PubMed ID
dgv133n67 CNV gain 20364138
dgv134n67 CNV gain 20364138
dgv135n67 CNV gain 20364138
esv3622584 CNV loss 21293372
nsv517469 CNV loss 19592680
nsv527055 CNV loss 19592680
nsv550200 CNV loss 21841781
nsv825289 CNV loss 20364138

Variation tolerance for MIR1915HG Gene

Residual Variation Intolerance Score: 81.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.05; 21.50% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MIR1915HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1915HG
Leiden Open Variation Database (LOVD)
MIR1915HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR1915HG Gene

Disorders for MIR1915HG Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR1915HG Gene - From: COP

Disorder Aliases PubMed IDs
prostate rhabdomyosarcoma
  • rhabdomyosarcoma of the prostate
prostate sarcoma
  • sarcoma of the prostate
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1915HG

genes like me logo Genes that share disorders with MIR1915HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1915HG Gene

Publications for MIR1915HG Gene

  1. Common variation at 10p12.31 near MLLT10 influences meningioma risk. (PMID: 21804547) Dobbins SE … Houlston RS (Nature genetics 2011) 2 3
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
  3. High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. (PMID: 26760575) Uren PJ … Penalva LO (RNA biology 2016) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K … Gorospe M (The EMBO journal 2009) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3

Products for MIR1915HG Gene

Sources for MIR1915HG Gene