microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1915 Gene

Data sources for MIR1915 Gene:

RNA type for MIR1915 Gene

miRNA

Aliases for MIR1915 Gene

External Ids for MIR1915 Gene

Previous HGNC Symbols for MIR1915 Gene

  • MIRN1915

Previous GeneCards Identifiers for MIR1915 Gene

  • GC00U923043
  • GC10M021826
  • GC10M021785

Summaries for MIR1915 Gene

Entrez Gene Summary for MIR1915 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1915 Gene

MIR1915 (MicroRNA 1915) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1915 include Lipoid Nephrosis.

Additional gene information for MIR1915 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1915 Gene

Genomics for MIR1915 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1915 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1915 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1915 Gene

Latest Assembly
chr10:21,496,562-21,496,641
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand

Previous Assembly
chr10:21,785,491-21,785,570
(GRCh37/hg19 by Entrez Gene)
Size:
80 bases
Orientation:
Minus strand

chr10:21,785,491-21,785,570
(GRCh37/hg19 by Ensembl)
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR1915 Gene

Genes around MIR1915 on UCSC Golden Path with GeneCards custom track
MIR1915 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1915 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1915 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1915 Gene

Proteins for MIR1915 Gene

Post-translational modifications for MIR1915 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1915 Gene

Domains & Families for MIR1915 Gene

Gene Families for MIR1915 Gene

HGNC:
genes like me logo Genes that share domains with MIR1915: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1915 Gene

Function for MIR1915 Gene

Phenotypes From GWAS Catalog for MIR1915 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1915 Gene

Localization for MIR1915 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1915 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
nucleus 1
endosome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1915 Gene

Pathways & Interactions for MIR1915 Gene

PathCards logo

SuperPathways for MIR1915 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1915 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1915 Gene

Drugs & Compounds for MIR1915 Gene

No Compound Related Data Available

Transcripts for MIR1915 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1915 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075B84E_9606 miRNA 22 4

RefSeq: NR_031736,

LncBase: hsa-miR-1915-5p,

miRBase: MIMAT0007891,

TarBase: hsa-miR-1915-5p,

URS000039BFD2_9606 miRNA 20 4

RefSeq: NR_031736,

LncBase: hsa-miR-1915-3p,

miRBase: MIMAT0007892,

TarBase: hsa-miR-1915-3p,

URS000075C681_9606 precursor_RNA 80 3

RefSeq: NR_031736,

Ensembl: ENST00000410139 (view in UCSC) ,

miRBase: MI0008336,

MIR1915 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1915 Gene

No ASD Table

Relevant External Links for MIR1915 Gene

GeneLoc Exon Structure for
MIR1915

No data available for mRNA/cDNA for MIR1915 Gene

Expression for MIR1915 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1915 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1915

genes like me logo Genes that share expression patterns with MIR1915: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1915 Gene

Orthologs for MIR1915 Gene

Evolution for MIR1915 Gene

ENSEMBL:
Gene Tree for MIR1915 (if available)
TreeFam:
Gene Tree for MIR1915 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1915

No data available for Orthologs for MIR1915 Gene

Paralogs for MIR1915 Gene

No data available for Paralogs for MIR1915 Gene

Variants for MIR1915 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1915 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1915 Gene

Variant ID Type Subtype PubMed ID
dgv133n67 CNV gain 20364138
dgv134n67 CNV gain 20364138
dgv135n67 CNV gain 20364138
esv3622584 CNV loss 21293372
nsv517469 CNV loss 19592680
nsv527055 CNV loss 19592680
nsv550200 CNV loss 21841781
nsv825289 CNV loss 20364138

Additional Variant Information for MIR1915 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1915
Leiden Open Variation Database (LOVD)
MIR1915

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1915 Gene

Disorders for MIR1915 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1915 Gene - From: COP

Disorder Aliases PubMed IDs
lipoid nephrosis
  • minimal change disease
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1915

genes like me logo Genes that share disorders with MIR1915: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1915 Gene

Publications for MIR1915 Gene

  1. Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p. (PMID: 33009394) Qu M … Pei X (Nature communications 2020) 3
  2. Up-Regulation of MiR-1915 Inhibits Proliferation, Invasion, and Migration of Helicobacter pylori-Infected Gastric Cancer Cells via Targeting RAGE. (PMID: 30554489) Xu XC … He TH (Yonsei medical journal 2019) 3
  3. miR-1915-3p inhibits Bcl-2 expression in the development of gastric cancer. (PMID: 31036603) Cui HW … Su XL (Bioscience reports 2019) 3
  4. Identification of serum miR-1915-3p and miR-455-3p as biomarkers for breast cancer. (PMID: 30048472) Guo J … Luo Y (PloS one 2018) 3
  5. MicroRNA‑1915‑3p prevents the apoptosis of lung cancer cells by downregulating DRG2 and PBX2. (PMID: 26572100) Xu C … Lu C (Molecular medicine reports 2016) 3

Products for MIR1915 Gene

Sources for MIR1915 Gene