Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR190B Gene

Subcategory (RNA class) for MIR190B Gene


Quality Score for this RNA gene is


Aliases for MIR190B Gene

  • MicroRNA 190b 2 3 5
  • Hsa-Mir-190b 3
  • Mir-190b 3
  • MIRN190B 3

External Ids for MIR190B Gene

Previous HGNC Symbols for MIR190B Gene

  • MIRN190B

Previous GeneCards Identifiers for MIR190B Gene

  • GC01M152436
  • GC01M154166

Summaries for MIR190B Gene

Entrez Gene Summary for MIR190B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR190B Gene

MIR190B (MicroRNA 190b) is an RNA Gene, and is affiliated with the undefined RNA class.

fRNAdb sequence ontologies for MIR190B Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

Additional gene information for MIR190B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR190B Gene

Genomics for MIR190B Gene

GeneHancer (GH) Regulatory Elements for MIR190B Gene

Promoters and enhancers for MIR190B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I154190 Promoter/Enhancer 1.7 EPDnew FANTOM5 Ensembl ENCODE 550.8 +1.4 1435 4.3 PKNOX1 NFIB NEUROD1 BMI1 ELK1 RCOR1 ZNF362 CEBPB ELF1 KAT8 MIR190B TPM3 HAX1 C1orf189 TDRD10 NUP210L CHRNB2 GC01M154167 RN7SL431P
GH01I154333 Enhancer 1.3 Ensembl ENCODE dbSUPER 10.3 -140.9 -140947 2.2 PKNOX1 FOXA2 ARID4B SIN3A ZNF48 YY1 ZNF121 ELK1 ZNF143 FOS UBE2Q1 IL6R IL6R-AS1 SNORA58B UBAP2L MIR190B TPM3 C1orf189 UBE2Q1-AS1 ATP8B2
GH01I154479 Enhancer 1.3 Ensembl ENCODE dbSUPER 9.2 -286.3 -286258 0.8 RB1 ARNT ARID4B ZNF2 RAD21 RFX5 YY1 CHAMP1 ZNF335 ZNF121 ENSG00000273110 IL6R UBE2Q1-AS1 UBE2Q1 TDRD10 SHE IL6R-AS1 CHRNB2 ILF2 CHTOP
GH01I154477 Enhancer 1 Ensembl ENCODE dbSUPER 9.2 -284.3 -284283 1.6 SMARCA5 CTCF TRIM22 MAX REST ZEB2 RAD21 ZNF664 ATF4 SMC3 ENSG00000273110 UBE2Q1-AS1 UBE2Q1 TDRD10 SHE IL6R IL6R-AS1 CHRNB2 RNU7-57P ATP8B2
GH01I154312 Enhancer 0.9 dbSUPER 10.1 -119.2 -119184 1.5 HDGF ATF1 ARNT YBX1 TCF12 GATA2 ARID2 FOS ATF7 GMEB1 ENSG00000278694 UBE2Q1 S100A4 RNU7-57P SNORA58B UBAP2L ILF2 CHTOP DCST1 TPM3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR190B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR190B Gene

Genomic Locations for MIR190B Gene
79 bases
Minus strand

Genomic View for MIR190B Gene

Genes around MIR190B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR190B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR190B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR190B Gene

ORGUL Member Location for MIR190B Gene

ORGUL Member Location for MIR190B gene

Proteins for MIR190B Gene

Post-translational modifications for MIR190B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR190B Gene

Domains & Families for MIR190B Gene

Gene Families for MIR190B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR190B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR190B Gene

Function for MIR190B Gene

Phenotypes From GWAS Catalog for MIR190B Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR190B Gene

Localization for MIR190B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR190B Gene

Pathways & Interactions for MIR190B Gene

SuperPathways for MIR190B Gene

No Data Available

Interacting Proteins for MIR190B Gene

Gene Ontology (GO) - Biological Process for MIR190B Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR190B Gene

Drugs & Compounds for MIR190B Gene

No Compound Related Data Available

Transcripts for MIR190B Gene

mRNA/cDNA for MIR190B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR190B Gene

No ASD Table

Relevant External Links for MIR190B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR190B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR190B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR190B Gene

Orthologs for MIR190B Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR190B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-190b 34
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-190b 34
  • 95 (a)
(Bos Taurus)
Mammalia bta-mir-190b 34
  • 93 (a)
(Monodelphis domestica)
Mammalia mdo-mir-190b 34
  • 92 (a)
(Mus musculus)
Mammalia Mir190b 34
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-190b 34
  • 42 (a)
(Gallus gallus)
Aves -- 34
  • 79 (a)
(Danio rerio)
Actinopterygii dre-mir-190b 34
  • 61 (a)
Species where no ortholog for MIR190B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR190B Gene

Gene Tree for MIR190B (if available)
Gene Tree for MIR190B (if available)

Paralogs for MIR190B Gene

No data available for Paralogs for MIR190B Gene

Variants for MIR190B Gene

Sequence variations from dbSNP and Humsavar for MIR190B Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000511471 -- 154,193,448(-) G/C downstream_transcript_variant
rs1000702169 -- 154,194,104(-) T/C upstream_transcript_variant
rs1000766298 -- 154,195,647(-) G/T upstream_transcript_variant
rs1002078064 -- 154,195,655(-) G/T upstream_transcript_variant
rs1002469149 -- 154,193,903(-) G/T upstream_transcript_variant

Additional Variant Information for MIR190B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR190B Gene

Disorders for MIR190B Gene

Additional Disease Information for MIR190B

No disorders were found for MIR190B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR190B Gene

Publications for MIR190B Gene

  1. MicroRNA-190b confers radio-sensitivity through negative regulation of Bcl-2 in gastric cancer cells. (PMID: 28044223) Wang C … Qiao C (Biotechnology letters 2017) 3 58
  2. MiR-190b, the highest up-regulated miRNA in ERα-positive compared to ERα-negative breast tumors, a new biomarker in breast cancers? (PMID: 26141719) Cizeron-Clairac G … Callens C (BMC cancer 2015) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR190B Gene

Sources for MIR190B Gene

Loading form....