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Aliases for MIR190A Gene

Subcategory (RNA class) for MIR190A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR190A Gene

  • MicroRNA 190a 2 3 5
  • MicroRNA 190 2 3
  • Hsa-Mir-190a 3
  • Hsa-Mir-190 3
  • Mir-190a 3
  • MiR-190 3
  • MIRN190 3
  • MIR190 3

External Ids for MIR190A Gene

Previous HGNC Symbols for MIR190A Gene

  • MIRN190
  • MIR190

Previous GeneCards Identifiers for MIR190A Gene

  • GC15P063117
  • GC15P063197
  • GC15P064358
  • GC15P064871
  • GC15P065753
  • GC15P063335
  • GC15P063774
  • GC15P064275
  • GC15P066324
  • GC15P066878
  • GC15P067407
  • GC15P067933

Summaries for MIR190A Gene

Entrez Gene Summary for MIR190A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR190A Gene

MIR190A (MicroRNA 190a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR190A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR190A Gene

Genomics for MIR190A Gene

GeneHancer (GH) Regulatory Elements for MIR190A Gene

Promoters and enhancers for MIR190A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I062823 Enhancer 0.5 ENCODE 550.8 +0.5 493 1.5 SP1 NFIL3 HLF FOS MIR190A PIR40223 TLN2
GH15I062824 Enhancer 0.2 ENCODE 550.8 -0.4 -443 0.3 MIR190A GC15M063885 TLN2
GH15I062893 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +73.7 73699 7.7 HDGF PKNOX1 CLOCK FOXA2 ZFP64 NEUROD1 SIN3A YBX1 ZBTB7B ETS1 ENSG00000259727 TPM1 TPM1-AS MIR190A PIR56499
GH15I062781 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.6 -40.8 -40830 3 PKNOX1 CLOCK NFIB ARID4B SIN3A RAD21 YY1 ZNF143 RCOR1 FOS MIR190A GC15M063885 TLN2
GH15I062844 Enhancer 1.2 Ensembl ENCODE dbSUPER 11.4 +24.4 24379 8.2 ELF3 PKNOX1 FOXA2 SIN3A RAD21 ZNF143 FOS DEK SMARCA5 RXRA MIR190A LOC105370854 GC15P069439 TLN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR190A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR190A Gene

Genomic Locations for MIR190A Gene
chr15:62,823,957-62,824,041
(GRCh38/hg38)
Size:
85 bases
Orientation:
Plus strand
chr15:63,116,156-63,116,240
(GRCh37/hg19)

Genomic View for MIR190A Gene

Genes around MIR190A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR190A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR190A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR190A Gene

Proteins for MIR190A Gene

Post-translational modifications for MIR190A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR190A Gene

Domains & Families for MIR190A Gene

Gene Families for MIR190A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR190A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR190A Gene

Function for MIR190A Gene

Phenotypes From GWAS Catalog for MIR190A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR190A Gene

Localization for MIR190A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR190A Gene

Pathways & Interactions for MIR190A Gene

SuperPathways for MIR190A Gene

No Data Available

Interacting Proteins for MIR190A Gene

Gene Ontology (GO) - Biological Process for MIR190A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR190A Gene

Drugs & Compounds for MIR190A Gene

No Compound Related Data Available

Transcripts for MIR190A Gene

mRNA/cDNA for MIR190A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR190A Gene

No ASD Table

Relevant External Links for MIR190A Gene

GeneLoc Exon Structure for
MIR190A
ECgene alternative splicing isoforms for
MIR190A

Expression for MIR190A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR190A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR190A Gene:

MIR190A
genes like me logo Genes that share expression patterns with MIR190A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR190A Gene

Orthologs for MIR190A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR190A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-190a 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-190a 34
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-190a 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-190a 34
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-190a 34
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir190 34
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-190 34
  • 98 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-190a 34
  • 54 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-190a 34
  • 57 (a)
OneToOne
Species where no ortholog for MIR190A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR190A Gene

ENSEMBL:
Gene Tree for MIR190A (if available)
TreeFam:
Gene Tree for MIR190A (if available)

Paralogs for MIR190A Gene

No data available for Paralogs for MIR190A Gene

Variants for MIR190A Gene

Sequence variations from dbSNP and Humsavar for MIR190A Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000806769 -- 62,822,753(+) A/G upstream_transcript_variant
rs1001018320 -- 62,822,907(+) G/A upstream_transcript_variant
rs1001314796 -- 62,823,599(+) A/G upstream_transcript_variant
rs1001662782 -- 62,823,279(+) A/C upstream_transcript_variant
rs1002724443 -- 62,822,364(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR190A Gene

Variant ID Type Subtype PubMed ID
nsv833032 CNV loss 17160897
nsv1562 CNV insertion 18451855
nsv1045036 CNV gain 25217958
nsv1035441 CNV gain 25217958

Additional Variant Information for MIR190A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR190A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR190A Gene

Disorders for MIR190A Gene

Additional Disease Information for MIR190A

No disorders were found for MIR190A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR190A Gene

Publications for MIR190A Gene

  1. MicroRNAs in pulmonary arterial hypertension: pathogenesis, diagnosis and treatment. (PMID: 25660363) Bienertova-Vasku J … Vasku A (Journal of the American Society of Hypertension : JASH 2015) 3 58
  2. The inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism. (PMID: 26314494) Xu S … Chen K (Scientific reports 2015) 3 58
  3. miR-190a inhibits epithelial-mesenchymal transition of hepatoma cells via targeting the long non-coding RNA treRNA. (PMID: 26608035) Wang X … Yang M (FEBS letters 2015) 3 58
  4. A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis. (PMID: 24009311) Chu HW … Yu JC (Human molecular genetics 2014) 3 58
  5. Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma. (PMID: 24586785) Hung TM … Lee PH (PloS one 2014) 3 58

Products for MIR190A Gene

Sources for MIR190A Gene

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