Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR1908 Gene

Subcategory (RNA class) for MIR1908 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1908 Gene

  • MicroRNA 1908 2 3 5
  • Hsa-Mir-1908 3
  • Mir-1908 3
  • MIRN1908 3

External Ids for MIR1908 Gene

Previous HGNC Symbols for MIR1908 Gene

  • MIRN1908

Previous GeneCards Identifiers for MIR1908 Gene

  • GC00U923135
  • GC11M061340
  • GC11M061582

Summaries for MIR1908 Gene

Entrez Gene Summary for MIR1908 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1908 Gene

MIR1908 (MicroRNA 1908) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are alpha-linolenic acid (ALA) metabolism and Metabolism.

Additional gene information for MIR1908 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1908 Gene

Genomics for MIR1908 Gene

GeneHancer (GH) Regulatory Elements for MIR1908 Gene

Promoters and enhancers for MIR1908 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I061813 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 -1.0 -968 4.5 HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 FADS2 MIR1908 FADS1 BEST1 EML3 PIR43939
GH11I061791 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 12.2 +22.5 22515 3.1 HDGF PKNOX1 CLOCK FOXA2 SMAD1 ARNT ARID4B SIN3A DMAP1 ZBTB7B FADS2 FEN1 MIR611 TMEM258 CPSF7 CSKMT GANAB TMEM138 EML3 TUT1
GH11I061812 Enhancer 0.6 ENCODE dbSUPER 0.8 +2.3 2336 0.1 POLR2A ZNF592 BEST1 MIR1908 FADS2 FADS1
GH11I061796 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 +17.4 17418 2 ZBTB40 ZNF2 RAD21 RFX5 YY1 POLR2B ARID2 SCRT2 ZNF143 RUNX3 FADS2 FADS1 DKFZP434K028 BEST1 FEN1 MIR1908 GC11P061758
GH11I061819 Enhancer 0.9 Ensembl ENCODE 0.4 -5.3 -5326 1.7 KLF1 RXRA MAFG ZNF592 FOSL1 ZNF316 ATF3 SCRT2 HNF4G FOSL2 FADS2 FEN1 MIR611 TMEM258 FADS1 PIR43939 MIR1908
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1908 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1908 Gene

Genomic Locations for MIR1908 Gene
chr11:61,815,161-61,815,240
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand
chr11:61,582,633-61,582,712
(GRCh37/hg19)

Genomic View for MIR1908 Gene

Genes around MIR1908 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1908 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1908 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1908 Gene

ORGUL Member Location for MIR1908 Gene

ORGUL Member Location for MIR1908 gene

Proteins for MIR1908 Gene

Post-translational modifications for MIR1908 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1908 Gene

Domains & Families for MIR1908 Gene

Gene Families for MIR1908 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1908: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1908 Gene

Function for MIR1908 Gene

Phenotypes From GWAS Catalog for MIR1908 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1908 Gene

Localization for MIR1908 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1908 Gene

Drugs & Compounds for MIR1908 Gene

No Compound Related Data Available

Transcripts for MIR1908 Gene

mRNA/cDNA for MIR1908 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1908 Gene

No ASD Table

Relevant External Links for MIR1908 Gene

GeneLoc Exon Structure for
MIR1908
ECgene alternative splicing isoforms for
MIR1908

Expression for MIR1908 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1908 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1908 Gene:

MIR1908
genes like me logo Genes that share expression patterns with MIR1908: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1908 Gene

Orthologs for MIR1908 Gene

Evolution for MIR1908 Gene

ENSEMBL:
Gene Tree for MIR1908 (if available)
TreeFam:
Gene Tree for MIR1908 (if available)

No data available for Orthologs for MIR1908 Gene

Paralogs for MIR1908 Gene

No data available for Paralogs for MIR1908 Gene

Variants for MIR1908 Gene

Sequence variations from dbSNP and Humsavar for MIR1908 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1001969539 -- 61,816,128(-) G/C upstream_transcript_variant
rs1003732447 -- 61,814,808(-) A/G downstream_transcript_variant
rs1004964674 -- 61,815,221(-) T/C non_coding_transcript_variant
rs1006483193 -- 61,816,469(-) G/A upstream_transcript_variant
rs1008508591 -- 61,815,885(-) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1908 Gene

Variant ID Type Subtype PubMed ID
nsv528697 CNV loss 19592680

Additional Variant Information for MIR1908 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1908

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1908 Gene

Disorders for MIR1908 Gene

Additional Disease Information for MIR1908

No disorders were found for MIR1908 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1908 Gene

Publications for MIR1908 Gene

  1. MicroRNA-1908 is a biomarker for poor prognosis in human osteosarcoma. (PMID: 27097944) Lian D … Liu NS (European review for medical and pharmacological sciences 2016) 3 58
  2. miR-1908 Overexpression Inhibits Proliferation, Changing Akt Activity and p53 Expression in Hypoxic NSCLC Cells. (PMID: 27178817) Ma Y … Kong R (Oncology research 2016) 3 58
  3. MiR-1908 promotes scar formation post-burn wound healing by suppressing Ski-mediated inflammation and fibroblast proliferation. (PMID: 27256397) Xie C … Yu J (Cell and tissue research 2016) 3 58
  4. The biological effects of hsa-miR-1908 in human adipocytes. (PMID: 25421647) Yang L … Ji CB (Molecular biology reports 2015) 3 58
  5. MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway. (PMID: 26265437) Xia X … He S (Molecular cancer 2015) 3 58

Products for MIR1908 Gene

Sources for MIR1908 Gene

Content
Loading form....