microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1825 Gene

Data sources for MIR1825 Gene:

RNA type for MIR1825 Gene

miRNA

Aliases for MIR1825 Gene

External Ids for MIR1825 Gene

Previous HGNC Symbols for MIR1825 Gene

  • MIRN1825

Previous GeneCards Identifiers for MIR1825 Gene

  • GC00U923067
  • GC20P030290
  • GC20P030825

Summaries for MIR1825 Gene

Entrez Gene Summary for MIR1825 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1825 Gene

MIR1825 (MicroRNA 1825) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Pre-NOTCH Expression and Processing and Signaling by GPCR.

Additional gene information for MIR1825 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1825 Gene

Genomics for MIR1825 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1825 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J032235 Enhancer 1.2 Ensembl ENCODE dbSUPER 250.7 -1.9 -1894 1.4 MXD4 HOMEZ THAP11 FOXA2 KDM6A MAFF SMAD4 RXRA SAP130 MIER3 MIR1825 lnc-KIF3B-1 piR-42344 piR-54610 TM9SF4 ASXL1 MCTS2P POFUT1 KIF3B
GH20J032237 Enhancer 0.5 dbSUPER 250.7 -0.2 -169 0.6 ZMYM3 ZNF623 RBM22 SUPT5H ZNF664 POLR2A KDM1A MIR1825 piR-42344 POFUT1 KIF3B
GH20J032236 Enhancer 0.5 dbSUPER 250.7 -0.9 -856 0.6 ZIC2 ZNF664 POLR2A EP300 KDM1A MIR1825 piR-42344 piR-54610 lnc-KIF3B-1 POFUT1 KIF3B
GH20J032179 Promoter/Enhancer 2.1 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.5 -49.6 -49577 17 ZNF600 SSRP1 POLR2A CEBPA ATF3 YY1 MXD4 KLF11 ZNF341 ZFP64 lnc-PLAGL2-4 TM9SF4 ASXL1 TSPY26P MIR1825 ENSG00000236772 MYLK2 POFUT1 NOL4L HSALNG0129557
GH20J032282 Enhancer 1.2 Ensembl ENCODE 11.4 +48.8 48833 9.3 SP1 MYC NCOR1 SSRP1 ZMYM3 KLF9 POLR2A CEBPA ATF3 ZSCAN16 TM9SF4 MIR1825 ASXL1 TSPY26P PLAGL2 POFUT1 ENSG00000236772 NOL4L HCK KIF3B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1825 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1825 Gene

Latest Assembly
chr20:32,237,795-32,237,847
(GRCh38/hg38)
Size:
53 bases
Orientation:
Plus strand

Previous Assembly
chr20:30,825,598-30,825,650
(GRCh37/hg19 by Entrez Gene)
Size:
53 bases
Orientation:
Plus strand

Genomic View for MIR1825 Gene

Genes around MIR1825 on UCSC Golden Path with GeneCards custom track
MIR1825 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1825 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1825 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1825 Gene

Proteins for MIR1825 Gene

Post-translational modifications for MIR1825 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1825 Gene

Domains & Families for MIR1825 Gene

Gene Families for MIR1825 Gene

HGNC:
genes like me logo Genes that share domains with MIR1825: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1825 Gene

Function for MIR1825 Gene

Phenotypes From GWAS Catalog for MIR1825 Gene

Gene Ontology (GO) - Molecular Function for MIR1825 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MIR1825: view

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1825 Gene

Localization for MIR1825 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1825 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MIR1825 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with MIR1825: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MIR1825 Gene

Pathways & Interactions for MIR1825 Gene

genes like me logo Genes that share pathways with MIR1825: view

Gene Ontology (GO) - Biological Process for MIR1825 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MIR1825: view

No data available for Interacting Proteins and SIGNOR curated interactions for MIR1825 Gene

Drugs & Compounds for MIR1825 Gene

No Compound Related Data Available

Transcripts for MIR1825 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1825 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075AF4A_9606 miRNA 18 4

RefSeq: NR_031726,

LncBase: hsa-miR-1825,

miRBase: MIMAT0006765,

TarBase: hsa-miR-1825,

URS000075E057_9606 pre_miRNA 53 3

RefSeq: NR_031726,

Ensembl: ENST00000408740 (view in UCSC) ,

miRBase: MI0008193,

MIR1825 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1825 Gene

No ASD Table

Relevant External Links for MIR1825 Gene

GeneLoc Exon Structure for
MIR1825

No data available for mRNA/cDNA for MIR1825 Gene

Expression for MIR1825 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1825 Gene

genes like me logo Genes that share expression patterns with MIR1825: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1825 Gene

Orthologs for MIR1825 Gene

Evolution for MIR1825 Gene

ENSEMBL:
Gene Tree for MIR1825 (if available)
TreeFam:
Gene Tree for MIR1825 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1825

No data available for Orthologs for MIR1825 Gene

Paralogs for MIR1825 Gene

No data available for Paralogs for MIR1825 Gene

Variants for MIR1825 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1825 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1825 Gene

Variant ID Type Subtype PubMed ID
nsv833954 CNV loss 17160897

Additional Variant Information for MIR1825 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1825
Leiden Open Variation Database (LOVD)
MIR1825

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1825 Gene

Disorders for MIR1825 Gene

Additional Disease Information for MIR1825

No disorders were found for MIR1825 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1825 Gene

Publications for MIR1825 Gene

  1. Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. (PMID: 30030593) Helferich AM … Weishaupt JH (Cellular and molecular life sciences : CMLS 2018) 3
  2. A novel serum microRNA-based identification and classification biomarker of human glioma. (PMID: 28475008) Xing W … Zeng C (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3
  3. Discovering microRNAs from deep sequencing data using miRDeep. (PMID: 18392026) Friedländer MR … Rajewsky N (Nature biotechnology 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1825 Gene

Sources for MIR1825 Gene