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Aliases for MIR1587 Gene

Subcategory (RNA class) for MIR1587 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1587 Gene

  • MicroRNA 1587 2 3 5
  • Hsa-Mir-1587 3

External Ids for MIR1587 Gene

Previous GeneCards Identifiers for MIR1587 Gene

  • GC0XU901745
  • GC0XM039696
  • GC0XP039698

Summaries for MIR1587 Gene

Entrez Gene Summary for MIR1587 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1587 Gene

MIR1587 (MicroRNA 1587) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1587 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1587 Gene

Genomics for MIR1587 Gene

GeneHancer (GH) Regulatory Elements for MIR1587 Gene

Promoters and enhancers for MIR1587 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI039815 Enhancer 1 Ensembl ENCODE 0.3 -20.7 -20693 3.2 RAD21 ETS1 EGR1 CREM EGR2 RXRA NCOA1 ELF1 NR2F2 ZNF592 GC0XP039804 MIR1587
GH0XI039813 Enhancer 0.9 Ensembl ENCODE 0.3 -23.6 -23585 1.5 CTCF MXI1 MAX RAD21 RFX5 POLR2A VEZF1 HNF4G SMC3 RCOR1 GC0XP039804 MIR1587
GH0XI039807 Enhancer 0.9 Ensembl ENCODE 0.3 -28.4 -28391 2.6 HDAC1 MEIS2 PKNOX1 JUN ETV1 GATA3 GATA2 RFX1 SOX6 NRF1 GC0XP039804 MIR1587 LOC105373177
GH0XI039820 Enhancer 0.6 Ensembl ENCODE 0.4 -16.4 -16370 2.2 L3MBTL2 RAD21 NR2F2 GC0XP039804 MIR1587
GH0XI039811 Enhancer 0.6 FANTOM5 0.3 -26.1 -26086 0.4 CTCF ZNF335 ATF1 POLR2A ZNF629 ZNF16 CREM BCOR MED14 GC0XP039804 MIR1587
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1587 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1587 Gene

Genomic Locations for MIR1587 Gene
chrX:39,837,561-39,837,613
(GRCh38/hg38)
Size:
53 bases
Orientation:
Plus strand
chrX:39,696,815-39,696,867
(GRCh37/hg19)

Genomic View for MIR1587 Gene

Genes around MIR1587 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1587 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1587 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1587 Gene

Proteins for MIR1587 Gene

Post-translational modifications for MIR1587 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1587 Gene

Domains & Families for MIR1587 Gene

Gene Families for MIR1587 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1587: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1587 Gene

Function for MIR1587 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1587 Gene

Localization for MIR1587 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1587 Gene

Pathways & Interactions for MIR1587 Gene

SuperPathways for MIR1587 Gene

No Data Available

Interacting Proteins for MIR1587 Gene

Gene Ontology (GO) - Biological Process for MIR1587 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1587 Gene

Drugs & Compounds for MIR1587 Gene

No Compound Related Data Available

Transcripts for MIR1587 Gene

mRNA/cDNA for MIR1587 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1587 Gene

No ASD Table

Relevant External Links for MIR1587 Gene

GeneLoc Exon Structure for
MIR1587
ECgene alternative splicing isoforms for
MIR1587

Expression for MIR1587 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1587 Gene:

MIR1587
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1587 Gene

Orthologs for MIR1587 Gene

Evolution for MIR1587 Gene

ENSEMBL:
Gene Tree for MIR1587 (if available)
TreeFam:
Gene Tree for MIR1587 (if available)

No data available for Orthologs for MIR1587 Gene

Paralogs for MIR1587 Gene

No data available for Paralogs for MIR1587 Gene

Variants for MIR1587 Gene

Sequence variations from dbSNP and Humsavar for MIR1587 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1001058930 -- 39,836,955(+) G/T upstream_transcript_variant
rs1001943489 -- 39,836,706(+) G/A upstream_transcript_variant
rs1003846343 -- 39,835,836(+) G/T upstream_transcript_variant
rs1005689749 -- 39,835,570(+) T/C upstream_transcript_variant
rs1006434548 -- 39,837,814(+) C/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1587 Gene

Variant ID Type Subtype PubMed ID
nsv436634 CNV deletion 17901297
esv32834 CNV loss 17666407

Additional Variant Information for MIR1587 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1587

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1587 Gene

Disorders for MIR1587 Gene

Additional Disease Information for MIR1587

No disorders were found for MIR1587 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1587 Gene

Publications for MIR1587 Gene

  1. Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587. (PMID: 28855213) Figueroa J … Lang FF (Cancer research 2017) 3 58
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1587 Gene

Sources for MIR1587 Gene

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