This gene represents a microRNA host gene. The long RNA transcribed from this gene is expressed at high levels in lymphoma and may function as an oncogene. [provided by RefSeq, Dec 2017] See more...

Aliases for MIR155HG Gene

Subcategory (RNA class) for MIR155HG Gene

lncRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR155HG Gene

  • MIR155 Host Gene 2 3 5
  • MIR155HG 2 5 165
  • MicroRNA Host Gene 2 (Non-Protein Coding) 2 3
  • B-Cell Receptor Inducible 2 3
  • BIC Transcript 2 3
  • NCRNA00172 2 3
  • BIC 2 3
  • MIR155 Host Gene (Non-Protein Coding) 2
  • Non-Protein Coding RNA 172 2
  • NONHSAG032560.2 91
  • HSALNG0132382 164
  • MIRHG2 3

External Ids for MIR155HG Gene

Previous HGNC Symbols for MIR155HG Gene

  • MIRHG2

Previous GeneCards Identifiers for MIR155HG Gene

  • GC21P025873
  • GC21P026934
  • GC21P012337

Summaries for MIR155HG Gene

Entrez Gene Summary for MIR155HG Gene

  • This gene represents a microRNA host gene. The long RNA transcribed from this gene is expressed at high levels in lymphoma and may function as an oncogene. [provided by RefSeq, Dec 2017]

GeneCards Summary for MIR155HG Gene

MIR155HG (MIR155 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR155HG include Malignant Glioma and Astrocytoma.

Rfam classification for MIR155HG Gene

Additional gene information for MIR155HG Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR155HG Gene

Genomics for MIR155HG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR155HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J025561 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +2.5 2502 4.2 SP1 KDM1A POLR2A ZNF143 RELA SMAD5 RAD21 TRIM22 EZH2 CTCF EU375836 MIR155HG JAM2 MRPL39 lnc-JAM2-1 lnc-MRPL39-2
GH21J025560 Promoter/Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 600.7 +0.0 40 0.5 POLR2A CEBPA CEBPB EU375836 MIR155HG lnc-MRPL39-2 JAM2
GH21J025559 Enhancer 0.4 FANTOM5 dbSUPER 600.7 -0.5 -473 0.1 MIR155HG lnc-MRPL39-2 piR-58510-008 JAM2
GH21J025420 Promoter/Enhancer 1.5 EPDnew FANTOM5 Ensembl ENCODE 11.7 -137.0 -137036 4.9 CTCF POLR2A STAT3 ZNF143 RELA SMAD5 RAD21 IKZF2 TRIM22 YY1 LINC00158 MIR155HG MIR155 MRPL39 lnc-MRPL39-18 lnc-MRPL39-19 JAM2
GH21J025486 Enhancer 1.2 FANTOM5 Ensembl ENCODE 11.3 -73.3 -73298 2.2 SP1 BACH1 JUND RELA SMAD5 TCF12 IKZF2 TRIM22 PKNOX1 EED MIR155HG MRPL39 lnc-MRPL39-16 SNODB1737 JAM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR155HG on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR155HG Gene

Genomic Locations for MIR155HG Gene
chr21:25,560,399-25,582,739
(GRCh38/hg38)
Size:
22,341 bases
Orientation:
Plus strand
chr21:26,934,221-26,947,480
(GRCh37/hg19)
Size:
13,260 bases
Orientation:
Plus strand

Genomic View for MIR155HG Gene

Genes around MIR155HG on UCSC Golden Path with GeneCards custom track
MIR155HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR155HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR155HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR155HG Gene

Proteins for MIR155HG Gene

Post-translational modifications for MIR155HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR155HG Gene

Domains & Families for MIR155HG Gene

Gene Families for MIR155HG Gene

genes like me logo Genes that share domains with MIR155HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR155HG Gene

Function for MIR155HG Gene

Phenotypes From GWAS Catalog for MIR155HG Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR155HG Gene

Localization for MIR155HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR155HG gene
Compartment Confidence
nucleus 3
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
cytosol 2
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR155HG Gene

Pathways & Interactions for MIR155HG Gene

PathCards logo

SuperPathways for MIR155HG Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR155HG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR155HG: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR155HG Gene

Drugs & Compounds for MIR155HG Gene

No Compound Related Data Available

Transcripts for MIR155HG Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR155HG Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00001C4928_9606 lncRNA 1600 3

Ensembl: ENST00000456917 (view in UCSC) ,

LNCipedia: MIR155HG:1,

NONCODE: NONHSAT081498.2,

URS000075EA4E_9606 lncRNA 1474 2

HGNC: 35460,

RefSeq: NR_001458,

URS0000EED0F1_9606 lncRNA 1497 1

Ensembl: ENST00000659862 (view in UCSC) ,

URS00008C0089_9606 lncRNA 5409 2

LNCipedia: MIR155HG:2,

NONCODE: NONHSAT081499.2,

URS00009BC295_9606 lncRNA 1600 2

LncBook: HSALNT0272107,

NONCODE: NONHSAT190773.1,

MIR155HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR155HG Gene

5 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR155HG Gene

No ASD Table

Relevant External Links for MIR155HG Gene

GeneLoc Exon Structure for
MIR155HG

Expression for MIR155HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR155HG Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR155HG

SOURCE GeneReport for Unigene cluster for MIR155HG Gene:

Hs.697120

Evidence on tissue expression from TISSUES for MIR155HG Gene

  • Skin(2.9)
  • Nervous system(2.8)
  • Blood(2.5)
  • Bone(2.3)
  • Muscle(2.2)
genes like me logo Genes that share expression patterns with MIR155HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR155HG Gene

Orthologs for MIR155HG Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR155HG Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-155 31
  • 98 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia cfa-mir-155 31
  • 95 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia bta-mir-155 31
  • 94 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Mir155 31
  • 91 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 85 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-155 31
  • 48 (a)
OneToOne
Chicken
(Gallus gallus)
Aves gga-mir-155 31
  • 92 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia aca-mir-155 31
  • 85 (a)
OneToOne
Zebrafish
(Danio rerio)
Actinopterygii dre-mir-155 31
  • 56 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea csa-mir-155 31
  • 12 (a)
OneToOne
Species where no ortholog for MIR155HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for MIR155HG Gene

ENSEMBL:
Gene Tree for MIR155HG (if available)
TreeFam:
Gene Tree for MIR155HG (if available)

Paralogs for MIR155HG Gene

No data available for Paralogs for MIR155HG Gene

Variants for MIR155HG Gene

Additional dbSNP identifiers (rs#s) for MIR155HG Gene

Additional Variant Information for MIR155HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR155HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR155HG Gene

Disorders for MIR155HG Gene

MalaCards: The human disease database

(18) MalaCards diseases for MIR155HG Gene - From: LncRNADisease, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR155HG

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with MIR155HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR155HG Gene

Publications for MIR155HG Gene

  1. Regulation of the MIR155 host gene in physiological and pathological processes. (PMID: 23246696) Elton TS … Parinandi NL (Gene 2013) 2 3
  2. MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. (PMID: 21296997) Vargova K … Stopka T (Blood 2011) 2 3
  3. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey LT … EPICURO/Spanish Bladder Cancer Study investigators (European urology 2010) 3 41
  4. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PMID: 19625176) Hosgood HD … Lan Q (Respiratory medicine 2009) 3 41
  5. [Expression and Prognostic Value of MiR-155 in Patients with Chronic Lymphocytic Leukemia]. (PMID: 32027250) Wang F … Li JY (Zhongguo shi yan xue ye xue za zhi 2020) 3

Products for MIR155HG Gene

Sources for MIR155HG Gene