microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1538 Gene

Subcategory (RNA class) for MIR1538 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR1538 Gene

  • MicroRNA 1538 2 3 5
  • Hsa-Mir-1538 3
  • MIMAT0007400 51
  • MI0007259 51
  • MIRN1538 3
  • MIR1538 2

External Ids for MIR1538 Gene

Previous HGNC Symbols for MIR1538 Gene

  • MIRN1538

Previous GeneCards Identifiers for MIR1538 Gene

  • GC00U923100
  • GC16M068158

Summaries for MIR1538 Gene

Entrez Gene Summary for MIR1538 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1538 Gene

MIR1538 (MicroRNA 1538) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1538 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1538 Gene

Genomics for MIR1538 Gene

GeneHancer (GH) Regulatory Elements for MIR1538 Gene

Promoters and enhancers for MIR1538 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1538 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1538 Gene

Genomic Locations for MIR1538 Gene
chr16:69,565,808-69,565,868
(GRCh38/hg38)
Size:
61 bases
Orientation:
Minus strand
chr16:69,599,711-69,599,771
(GRCh37/hg19)
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR1538 Gene

Genes around MIR1538 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1538 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1538 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1538 Gene

Proteins for MIR1538 Gene

Post-translational modifications for MIR1538 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1538 Gene

Domains & Families for MIR1538 Gene

Gene Families for MIR1538 Gene

HGNC:
genes like me logo Genes that share domains with MIR1538: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1538 Gene

Function for MIR1538 Gene

Phenotypes From GWAS Catalog for MIR1538 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1538 Gene

Localization for MIR1538 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1538 Gene

Pathways & Interactions for MIR1538 Gene

PathCards logo

SuperPathways for MIR1538 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR1538 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1538 Gene

Drugs & Compounds for MIR1538 Gene

No Compound Related Data Available

Transcripts for MIR1538 Gene

mRNA/cDNA for MIR1538 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1538 Gene

No ASD Table

Relevant External Links for MIR1538 Gene

GeneLoc Exon Structure for
MIR1538

Expression for MIR1538 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1538 Gene

Orthologs for MIR1538 Gene

Evolution for MIR1538 Gene

ENSEMBL:
Gene Tree for MIR1538 (if available)
TreeFam:
Gene Tree for MIR1538 (if available)

No data available for Orthologs for MIR1538 Gene

Paralogs for MIR1538 Gene

No data available for Paralogs for MIR1538 Gene

Variants for MIR1538 Gene

Additional dbSNP identifiers (rs#s) for MIR1538 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1538 Gene

Variant ID Type Subtype PubMed ID
nsv1852 CNV deletion 18451855

Additional Variant Information for MIR1538 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1538

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1538 Gene

Disorders for MIR1538 Gene

Additional Disease Information for MIR1538

No disorders were found for MIR1538 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1538 Gene

Publications for MIR1538 Gene

  1. Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing. (PMID: 18524951) Azuma-Mukai A … Siomi MC (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR1538 Gene

Sources for MIR1538 Gene