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Aliases for MIR1343 Gene

Subcategory (RNA class) for MIR1343 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR1343 Gene

  • MicroRNA 1343 2 3 5
  • Hsa-Mir-1343 3

External Ids for MIR1343 Gene

Previous GeneCards Identifiers for MIR1343 Gene

  • GC11U901867

Summaries for MIR1343 Gene

Entrez Gene Summary for MIR1343 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1343 Gene

MIR1343 (MicroRNA 1343) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1343 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1343 Gene

Genomics for MIR1343 Gene

GeneHancer (GH) Regulatory Elements for MIR1343 Gene

Promoters and enhancers for MIR1343 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J034940 Enhancer 0.5 Ensembl 600.7 -1.2 -1237 0.4 RELA CTCF RUNX3 RAD21 ZNF217 MIR1343 APIP PDHX
GH11J034943 Enhancer 0.2 ENCODE 600.7 +1.9 1932 0.2 MIR1343 PDHX GC11P034975
GH11J035157 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.2 +224.9 224867 18.4 SP1 ELF3 CBFA2T2 CEBPG RELA HNF1A PPARG CREM MLLT1 RAD21 CD44 LOC100507144 MIR1343 PDHX APIP ENSG00000255004 GC11P035210
GH11J035389 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 11.5 +449.4 449385 3.5 ELF3 CC2D1A CTCF ZNF148 CEBPG NCOA3 MAFK SP1 CREM ZNF644 SLC1A2 APIP ENSG00000255542 PDHX MIR1343 ENSG00000215380 GC11P035411
GH11J035329 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 11.1 +393.5 393464 12.2 SP1 ELF3 ZKSCAN8 CBFA2T2 ZNF148 CEBPG ZSCAN21 BACH1 TRIM24 PPARG ENSG00000255004 CD44 MIR1343 SLC1A2 ENSG00000215380
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1343 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1343 Gene

Genomic Locations for MIR1343 Gene
chr11:34,941,837-34,941,920
(GRCh38/hg38)
Size:
84 bases
Orientation:
Plus strand
chr11:34,963,384-34,963,467
(GRCh37/hg19)
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR1343 Gene

Genes around MIR1343 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1343 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1343 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1343 Gene

Proteins for MIR1343 Gene

Post-translational modifications for MIR1343 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1343 Gene

Domains & Families for MIR1343 Gene

Gene Families for MIR1343 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1343: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1343 Gene

Function for MIR1343 Gene

Phenotypes From GWAS Catalog for MIR1343 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1343 Gene

Localization for MIR1343 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1343 Gene

Pathways & Interactions for MIR1343 Gene

PathCards logo

SuperPathways for MIR1343 Gene

No Data Available

Interacting Proteins for MIR1343 Gene

Gene Ontology (GO) - Biological Process for MIR1343 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1343 Gene

Drugs & Compounds for MIR1343 Gene

No Compound Related Data Available

Transcripts for MIR1343 Gene

mRNA/cDNA for MIR1343 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1343 Gene

No ASD Table

Relevant External Links for MIR1343 Gene

GeneLoc Exon Structure for
MIR1343
ECgene alternative splicing isoforms for
MIR1343

Expression for MIR1343 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1343 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1343 Gene:

MIR1343
genes like me logo Genes that share expression patterns with MIR1343: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1343 Gene

Orthologs for MIR1343 Gene

Evolution for MIR1343 Gene

ENSEMBL:
Gene Tree for MIR1343 (if available)
TreeFam:
Gene Tree for MIR1343 (if available)

No data available for Orthologs for MIR1343 Gene

Paralogs for MIR1343 Gene

No data available for Paralogs for MIR1343 Gene

Variants for MIR1343 Gene

Sequence variations from dbSNP and Humsavar for MIR1343 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1001577601 -- 34,940,193(+) A/G upstream_transcript_variant
rs1004236727 -- 34,939,853(+) G/T upstream_transcript_variant
rs1004568741 -- 34,942,364(+) G/A downstream_transcript_variant
rs1004871628 -- 34,939,965(+) G/T upstream_transcript_variant
rs1005007605 -- 34,940,254(+) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1343 Gene

Variant ID Type Subtype PubMed ID
esv2759817 CNV loss 17122850
nsv1042014 CNV loss 25217958
nsv832119 CNV gain 17160897

Additional Variant Information for MIR1343 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1343

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1343 Gene

Disorders for MIR1343 Gene

Additional Disease Information for MIR1343

No disorders were found for MIR1343 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1343 Gene

Publications for MIR1343 Gene

  1. miR-1343 attenuates pathways of fibrosis by targeting the TGF-β receptors. (PMID: 26542979) Stolzenburg LR … Harris A (The Biochemical journal 2016) 2 3 58
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1343 Gene

Sources for MIR1343 Gene

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