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Aliases for MIR133A2 Gene

Subcategory (RNA class) for MIR133A2 Gene


Quality Score for this RNA gene is


Aliases for MIR133A2 Gene

  • MicroRNA 133a-2 2 3 5
  • Hsa-Mir-133a-2 3
  • Mir-133a-2 3
  • MIRN133A2 3

External Ids for MIR133A2 Gene

ORGUL Members for MIR133A2 Gene

Previous HGNC Symbols for MIR133A2 Gene

  • MIRN133A2

Previous GeneCards Identifiers for MIR133A2 Gene

  • GC20P060573
  • GC20P061162
  • GC20P062653
  • GC20P062659
  • GC20P062715
  • GC20P062778
  • GC20P062785
  • GC20P062790
  • GC20P062802
  • GC20P062811

Summaries for MIR133A2 Gene

Entrez Gene Summary for MIR133A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR133A2 Gene

MIR133A2 (MicroRNA 133a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and TarBasePathway.

Additional gene information for MIR133A2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR133A2 Gene

Genomics for MIR133A2 Gene

GeneHancer (GH) Regulatory Elements for MIR133A2 Gene

Promoters and enhancers for MIR133A2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J062708 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE dbSUPER 10.2 +146.0 146013 4.3 PKNOX1 ATF1 RB1 NFIB KLF17 SIN3A YY1 ZNF766 GLIS2 SCRT2 NTSR1 ENSG00000223669 OGFR OGFR-AS1 SLCO4A1-AS1 SLCO4A1 MRGBP ENSG00000229882 ENSG00000232121 MIR133A2
GH20J062589 Enhancer 1.1 FANTOM5 ENCODE dbSUPER 12.1 +25.3 25266 1.8 ELK4 MXI1 MAZ SMARCC1 MAX PAX8 MNT SMARCB1 RAD21 GABPA MIR1-1HG MIR1-1HG-AS1 MIR133A2 ENSG00000229882 ENSG00000232121 MIR1-1 ENSG00000264490 WI2-87327B8.2
GH20J062452 Enhancer 0.8 ENCODE 11.4 -112.1 -112106 0.9 NFIB NEUROD1 NFXL1 PLRG1 BMI1 ZNF48 ZNF366 RCOR1 SMARCA5 GATAD2B MIR133A2 MIR1-1HG MIR1-1HG-AS1 MIR1-1 GATA5 LOC105372710
GH20J062595 Enhancer 0.7 ENCODE 12 +30.8 30817 0.2 KLF1 MAX KLF17 ZIC2 ZBTB7B ZNF335 ZFHX2 GLIS2 POLR2A EGR1 ENSG00000229882 ENSG00000232121 MIR133A2 MIR1-1 MIR1-1HG-AS1 MIR1-1HG WI2-87327B8.2 ENSG00000264490
GH20J062715 Enhancer 0.7 ENCODE dbSUPER 11.1 +151.5 151497 1 FOSL1 L3MBTL2 MGA ZNF395 OGFR OGFR-AS1 LINC00659 SLCO4A1-AS1 SLCO4A1 MIR133A2 MRGBP ENSG00000229882 ENSG00000232121 NTSR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR133A2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR133A2 Gene

Genomic Locations for MIR133A2 Gene
102 bases
Plus strand
102 bases
Plus strand

Genomic View for MIR133A2 Gene

Genes around MIR133A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR133A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR133A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR133A2 Gene

Proteins for MIR133A2 Gene

Post-translational modifications for MIR133A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR133A2 Gene

Domains & Families for MIR133A2 Gene

Gene Families for MIR133A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR133A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR133A2 Gene

Function for MIR133A2 Gene

Gene Ontology (GO) - Molecular Function for MIR133A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 22163007
genes like me logo Genes that share ontologies with MIR133A2: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR133A2 Gene

Localization for MIR133A2 Gene

Gene Ontology (GO) - Cellular Components for MIR133A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 20159880
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with MIR133A2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR133A2 Gene

Pathways & Interactions for MIR133A2 Gene

SuperPathways for MIR133A2 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
2 TarBasePathway
genes like me logo Genes that share pathways with MIR133A2: view

Pathways by source for MIR133A2 Gene

1 BioSystems pathway for MIR133A2 Gene
1 KEGG pathway for MIR133A2 Gene

Interacting Proteins for MIR133A2 Gene

Gene Ontology (GO) - Biological Process for MIR133A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007194 negative regulation of adenylate cyclase activity ISS --
GO:0010455 positive regulation of cell fate commitment ISS --
GO:0010614 negative regulation of cardiac muscle hypertrophy ISS --
GO:0010628 positive regulation of gene expression IDA 23069713
GO:0010667 negative regulation of cardiac muscle cell apoptotic process ISS --
genes like me logo Genes that share ontologies with MIR133A2: view

No data available for SIGNOR curated interactions for MIR133A2 Gene

Drugs & Compounds for MIR133A2 Gene

No Compound Related Data Available

Transcripts for MIR133A2 Gene

mRNA/cDNA for MIR133A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(3) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR133A2 Gene

No ASD Table

Relevant External Links for MIR133A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR133A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR133A2 Gene

mRNA differential expression in normal tissues according to GTEx for MIR133A2 Gene

This gene is overexpressed in Muscle - Skeletal (x51.1).

NURSA nuclear receptor signaling pathways regulating expression of MIR133A2 Gene:

genes like me logo Genes that share expression patterns with MIR133A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR133A2 Gene

Orthologs for MIR133A2 Gene

Evolution for MIR133A2 Gene

Gene Tree for MIR133A2 (if available)
Gene Tree for MIR133A2 (if available)

No data available for Orthologs for MIR133A2 Gene

Paralogs for MIR133A2 Gene

No data available for Paralogs for MIR133A2 Gene

Variants for MIR133A2 Gene

Sequence variations from dbSNP and Humsavar for MIR133A2 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1003796672 -- 62,563,854(+) G/A upstream_transcript_variant
rs1008219916 -- 62,564,560(+) C/T upstream_transcript_variant
rs1008556618 -- 62,565,413(+) C/T downstream_transcript_variant
rs1010038481 -- 62,563,297(+) C/A upstream_transcript_variant
rs1014398000 -- 62,564,071(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR133A2 Gene

Variant ID Type Subtype PubMed ID
nsv953302 CNV deletion 24416366
nsv586501 CNV gain 21841781
nsv586496 CNV gain 21841781
nsv470556 CNV loss 18288195
nsv459068 CNV gain 19166990
nsv459065 CNV gain 19166990
esv2422398 CNV duplication 17116639
dgv4344n100 CNV gain 25217958
dgv4343n100 CNV gain 25217958

Additional Variant Information for MIR133A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR133A2 Gene

Disorders for MIR133A2 Gene

Additional Disease Information for MIR133A2

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR133A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR133A2 Gene

Publications for MIR133A2 Gene

  1. Analysis of the Micro-RNA-133 and PITX3 genes in Parkinson's disease. (PMID: 20468068) de Mena L … Alvarez V (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010) 3 44 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. Comparative microRNA profiling in relation to urinary albumin excretion in newly diagnosed hypertensive patients. (PMID: 26984682) Parthenakis FI … Vardas PE (Journal of human hypertension 2016) 3 58
  4. miR-150-5p and miR-133a suppress glioma cell proliferation and migration through targeting membrane-type-1 matrix metalloproteinase. (PMID: 27154818) Sakr M … Sato H (Gene 2016) 3 58
  5. Tumor suppressor role of miR-133a in gastric cancer by repressing IGF1R. (PMID: 25780292) Gong Y … Tang LM (World journal of gastroenterology 2015) 3 58

Products for MIR133A2 Gene

Sources for MIR133A2 Gene

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