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Aliases for MIR133A1 Gene

Subcategory (RNA class) for MIR133A1 Gene


Quality Score for this RNA gene is


Aliases for MIR133A1 Gene

  • MicroRNA 133a-1 2 3 5
  • Hsa-Mir-133a-1 3
  • Mir-133a-1 3
  • MIRN133A1 3

External Ids for MIR133A1 Gene

Previous HGNC Symbols for MIR133A1 Gene

  • MIRN133A1

Previous GeneCards Identifiers for MIR133A1 Gene

  • GC18M017666
  • GC18M019405

Summaries for MIR133A1 Gene

Entrez Gene Summary for MIR133A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR133A1 Gene

MIR133A1 (MicroRNA 133a-1) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR133A1 include Bladder Carcinoma In Situ. Among its related pathways are MicroRNAs in cancer and TarBasePathway.

Additional gene information for MIR133A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR133A1 Gene

Genomics for MIR133A1 Gene

GeneHancer (GH) Regulatory Elements for MIR133A1 Gene

Promoters and enhancers for MIR133A1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J021852 Enhancer 0.7 Ensembl ENCODE 11.3 -27.3 -27301 1.1 SPI1 PKNOX1 RUNX3 HDGF RPL34P32 ENSG00000199977 MIR1-2 MIR133A1 MIR320C1 MIR133A1HG MIB1
GH18J021803 Enhancer 0.5 Ensembl 12.2 +22.3 22284 0.2 SOX13 CEBPB KDM1A HLF MIB1 MIR133A1 MIR320C1 RN7SL233P GC18P021818
GH18J021804 Enhancer 0.4 Ensembl 12.2 +21.7 21684 0.6 SOX13 KDM1A MIR133A1 MIR320C1 MIB1 GC18P021818 RN7SL233P
GH18J021825 Enhancer 0.6 ENCODE 0.7 -3.7 -3740 7.9 MLLT1 MAFK ZNF316 MAFG ZBTB17 MAFF BACH1 EMSY HNF4A MIR133A1HG MIR1-2 MIB1 MIR320C1 ABHD3 GC18P021825 MIR133A1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR133A1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR133A1 Gene

Genomic Locations for MIR133A1 Gene
88 bases
Minus strand
5,924 bases
Minus strand

Genomic View for MIR133A1 Gene

Genes around MIR133A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR133A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR133A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR133A1 Gene

Proteins for MIR133A1 Gene

Post-translational modifications for MIR133A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR133A1 Gene

Domains & Families for MIR133A1 Gene

Gene Families for MIR133A1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR133A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR133A1 Gene

Function for MIR133A1 Gene

Gene Ontology (GO) - Molecular Function for MIR133A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 21109942
genes like me logo Genes that share ontologies with MIR133A1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR133A1 Gene

Localization for MIR133A1 Gene

Gene Ontology (GO) - Cellular Components for MIR133A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 20159880
GO:0005622 intracellular IEA --
GO:0035068 micro-ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with MIR133A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR133A1 Gene

Pathways & Interactions for MIR133A1 Gene

SuperPathways for MIR133A1 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
2 TarBasePathway
genes like me logo Genes that share pathways with MIR133A1: view

Pathways by source for MIR133A1 Gene

1 BioSystems pathway for MIR133A1 Gene
1 KEGG pathway for MIR133A1 Gene

Interacting Proteins for MIR133A1 Gene

Gene Ontology (GO) - Biological Process for MIR133A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010455 positive regulation of cell fate commitment ISS --
GO:0010614 negative regulation of cardiac muscle hypertrophy ISS --
GO:0010628 positive regulation of gene expression IDA 23069713
GO:0010667 negative regulation of cardiac muscle cell apoptotic process ISS --
GO:0010831 positive regulation of myotube differentiation ISS --
genes like me logo Genes that share ontologies with MIR133A1: view

No data available for SIGNOR curated interactions for MIR133A1 Gene

Drugs & Compounds for MIR133A1 Gene

No Compound Related Data Available

Transcripts for MIR133A1 Gene

mRNA/cDNA for MIR133A1 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR133A1 Gene

No ASD Table

Relevant External Links for MIR133A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR133A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR133A1 Gene:

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR133A1 Gene

Orthologs for MIR133A1 Gene

Evolution for MIR133A1 Gene

Gene Tree for MIR133A1 (if available)
Gene Tree for MIR133A1 (if available)

No data available for Orthologs for MIR133A1 Gene

Paralogs for MIR133A1 Gene

No data available for Paralogs for MIR133A1 Gene

Variants for MIR133A1 Gene

Sequence variations from dbSNP and Humsavar for MIR133A1 Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs1000882824 -- 21,826,465(-) T/C upstream_transcript_variant
rs1002195393 -- 21,825,632(-) A/G downstream_transcript_variant
rs1002256781 -- 21,825,357(-) A/AA downstream_transcript_variant
rs1004501796 -- 21,825,521(-) C/G downstream_transcript_variant
rs1008107368 -- 21,826,842(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR133A1 Gene

Variant ID Type Subtype PubMed ID
nsv2222 CNV insertion 18451855

Additional Variant Information for MIR133A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR133A1 Gene

Disorders for MIR133A1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR133A1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
bladder carcinoma in situ
  • bladder ca in situ
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR133A1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MIR133A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR133A1 Gene

Publications for MIR133A1 Gene

  1. Analysis of the Micro-RNA-133 and PITX3 genes in Parkinson's disease. (PMID: 20468068) de Mena L … Alvarez V (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010) 3 45 58
  2. miR-133 involves in lung adenocarcinoma cell metastasis by targeting FLOT2. (PMID: 28503944) Wei G … Yan J (Artificial cells, nanomedicine, and biotechnology 2018) 3 58
  3. MicroRNA-133a acts as a tumour suppressor in breast cancer through targeting LASP1. (PMID: 29207145) Sui Y … Wang M (Oncology reports 2018) 3 58
  4. Down-regulation of MicroRNA-133 predicts poor overall survival and regulates the growth and invasive abilities in glioma. (PMID: 28376685) Liu Y … Yang B (Artificial cells, nanomedicine, and biotechnology 2018) 3 58
  5. miR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer. (PMID: 28748780) Zhou GQ … He SB (Oncology research 2018) 3 58

Products for MIR133A1 Gene

Sources for MIR133A1 Gene

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