microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1323 Gene

Data sources for MIR1323 Gene:

RNA type for MIR1323 Gene

miRNA

Aliases for MIR1323 Gene

External Ids for MIR1323 Gene

Previous HGNC Symbols for MIR1323 Gene

  • MIRN1323

Previous GeneCards Identifiers for MIR1323 Gene

  • GC00U922858
  • GC19P058868
  • GC19P054175
  • GC19P053673
  • GC19P053678
  • GC19P053969
  • GC19P054003
  • GC19P054029
  • GC19P054089
  • GC19P053687
  • GC19P053718
  • GC19P053753
  • GC19P053781
  • GC19P053795
  • GC19P053860
  • GC19P053911
  • GC19P053943
  • GC19P054605
  • GC19P055555

Summaries for MIR1323 Gene

Entrez Gene Summary for MIR1323 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1323 Gene

MIR1323 (MicroRNA 1323) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1323 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1323 Gene

Genomics for MIR1323 Gene

Genomic Locations for MIR1323 Gene

Latest Assembly
chr19:53,671,968-53,672,040
(GRCh38/hg38)
Size:
73 bases
Orientation:
Plus strand

Previous Assembly
chr19:54,175,222-54,175,294
(GRCh37/hg19 by Entrez Gene)
Size:
73 bases
Orientation:
Plus strand

chr19:54,175,222-54,175,294
(GRCh37/hg19 by Ensembl)
Size:
73 bases
Orientation:
Plus strand

Genomic View for MIR1323 Gene

Genes around MIR1323 on UCSC Golden Path with GeneCards custom track
MIR1323 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR1323 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1323 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1323 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR1323 Gene

Proteins for MIR1323 Gene

Post-translational modifications for MIR1323 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1323 Gene

Domains & Families for MIR1323 Gene

Gene Families for MIR1323 Gene

HGNC:
genes like me logo Genes that share domains with MIR1323: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1323 Gene

Function for MIR1323 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1323 Gene

Localization for MIR1323 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1323 Gene

Pathways & Interactions for MIR1323 Gene

PathCards logo

SuperPathways for MIR1323 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1323 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1323 Gene

Drugs & Compounds for MIR1323 Gene

No Compound Related Data Available

Transcripts for MIR1323 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1323 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075B58C_9606 precursor_RNA 73 4

RefSeq: NR_031568,

Ensembl: ENST00000408090 (view in UCSC) ,

miRBase: MI0003786,

ENA: LM609628.1:1..73:precursor_RNA,

URS000058276F_9606 miRNA 22 4

RefSeq: NR_031568,

miRBase: MIMAT0005795,

MirGeneDB: Hsa-Mir-1323_5p,

ENA: AB372684.1:1..22:ncRNA, LM380642.1:1..22:ncRNA, LM609628.1:11..32:ncRNA,

URS0000EFCC70_9606 precursor_RNA 57 1

MirGeneDB: Hsa-Mir-1323,

URS00007E4C0F_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-1323_3p,

MIR1323 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1323 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1323 Gene

No ASD Table

Relevant External Links for MIR1323 Gene

GeneLoc Exon Structure for
MIR1323

Expression for MIR1323 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1323

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1323 Gene

Orthologs for MIR1323 Gene

Evolution for MIR1323 Gene

ENSEMBL:
Gene Tree for MIR1323 (if available)
TreeFam:
Gene Tree for MIR1323 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR1323

No data available for Orthologs for MIR1323 Gene

Paralogs for MIR1323 Gene

No data available for Paralogs for MIR1323 Gene

Variants for MIR1323 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR1323 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR1323 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV deletion 23290073
esv2762049 CNV gain 21179565
nsv1055718 CNV gain 25217958
nsv580107 CNV gain 21841781

Additional Variant Information for MIR1323 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1323
Leiden Open Variation Database (LOVD)
MIR1323

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1323 Gene

Disorders for MIR1323 Gene

Additional Disease Information for MIR1323

No disorders were found for MIR1323 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1323 Gene

Publications for MIR1323 Gene

  1. Circular RNA_LARP4 Sponges miR-1323 and Hampers Progression of Esophageal Squamous Cell Carcinoma Through Modulating PTEN/PI3K/AKT Pathway. (PMID: 31897898) Chen Z … Shao Q (Digestive diseases and sciences 2020) 3
  2. MicroRNA-1323 downregulation promotes migration and invasion of breast cancer cells by targeting tumour protein D52. (PMID: 32211853) Xu Y … Liu M (Journal of biochemistry 2020) 3
  3. Knockdown of microRNA-1323 restores sensitivity to radiation by suppression of PRKDC activity in radiation-resistant lung cancer cells. (PMID: 25823795) Li Y … Li H (Oncology reports 2015) 3
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  5. New miRNAs cloned from neuroblastoma. (PMID: 18230126) Afanasyeva EA … Westermann F (BMC genomics 2008) 3

Products for MIR1323 Gene

Sources for MIR1323 Gene