microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1304 Gene

Subcategory (RNA class) for MIR1304 Gene

miRNA

Quality Score for this RNA gene is

16

Aliases for MIR1304 Gene

  • MicroRNA 1304 2 3 5
  • Hsa-MiR-1304-5p 168 179
  • Hsa-MiR-1304-3p 168 179
  • Hsa-Mir-1304 3
  • MIMAT0022720 53
  • MIMAT0005892 53
  • MI0006371 53
  • MIRN1304 3
  • MIR1304 2

External Ids for MIR1304 Gene

Previous HGNC Symbols for MIR1304 Gene

  • MIRN1304

Previous GeneCards Identifiers for MIR1304 Gene

  • GC00U922944
  • GC11M093196
  • GC11M093466
  • GC11M093739
  • GC11M093751
  • GC11M093947
  • GC11M094035
  • GC11M093761
  • GC11M093771
  • GC11M093780
  • GC11M093791
  • GC11M093802
  • GC11M093811
  • GC11M093941
  • GC11M093927

Summaries for MIR1304 Gene

Entrez Gene Summary for MIR1304 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1304 Gene

MIR1304 (MicroRNA 1304) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1304 include Hypopharynx Cancer. Among its related pathways are RNA Polymerase I Promoter Escape and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.

Additional gene information for MIR1304 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1304 Gene

Genomics for MIR1304 Gene

GeneHancer (GH) Regulatory Elements for MIR1304 Gene

Promoters and enhancers for MIR1304 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J093731 Enhancer 0.6 Ensembl ENCODE 750.6 +1.4 1371 1.2 POLR2A ZBED1 SUPT5H MIR1304 NONHSAG009375.2 SNORA1 SNORA18 SNORA25 SNORA32 SNORA8 SNORD5 SNORD6 piR-31447
GH11J093733 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -6.2 -6191 13.2 SIN3A CTCF ZBTB6 MLX RBPJ SMARCE1 POLR2A USF2 NR2F6 ATF1 C11orf54 TAF1D ENSG00000284057 NONHSAG009376.2 lnc-VSTM5-1 MED17 CEP295 ANKRD49 MRE11 SNORA1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1304 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1304 Gene

Genomic Locations for MIR1304 Gene
chr11:93,733,674-93,733,764
(GRCh38/hg38)
Size:
91 bases
Orientation:
Minus strand
chr11:93,466,840-93,466,930
(GRCh37/hg19)
Size:
91 bases
Orientation:
Minus strand

Genomic View for MIR1304 Gene

Genes around MIR1304 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1304 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1304 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1304 Gene

Proteins for MIR1304 Gene

Post-translational modifications for MIR1304 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1304 Gene

Domains & Families for MIR1304 Gene

Gene Families for MIR1304 Gene

HGNC:
genes like me logo Genes that share domains with MIR1304: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1304 Gene

Function for MIR1304 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1304 Gene

Localization for MIR1304 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1304 Gene

Pathways & Interactions for MIR1304 Gene

genes like me logo Genes that share pathways with MIR1304: view

Gene Ontology (GO) - Biological Process for MIR1304 Gene

None

No data available for SIGNOR curated interactions for MIR1304 Gene

Drugs & Compounds for MIR1304 Gene

No Compound Related Data Available

Transcripts for MIR1304 Gene

mRNA/cDNA for MIR1304 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNACentral transcripts :
(3) miRBase transcripts :
(2) TarBase transcripts :
(4) ENA transcripts :
(2) LncBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1304 Gene

No ASD Table

Relevant External Links for MIR1304 Gene

GeneLoc Exon Structure for
MIR1304
ECgene alternative splicing isoforms for
MIR1304

Expression for MIR1304 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1304 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1304 Gene:

MIR1304
genes like me logo Genes that share expression patterns with MIR1304: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1304 Gene

Orthologs for MIR1304 Gene

Evolution for MIR1304 Gene

ENSEMBL:
Gene Tree for MIR1304 (if available)
TreeFam:
Gene Tree for MIR1304 (if available)

No data available for Orthologs for MIR1304 Gene

Paralogs for MIR1304 Gene

No data available for Paralogs for MIR1304 Gene

Variants for MIR1304 Gene

Sequence variations from dbSNP and Humsavar for MIR1304 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000687560 -- 93,735,293(-) T/C upstream_transcript_variant
rs1000823478 -- 93,735,035(-) T/G upstream_transcript_variant
rs1001479163 -- 93,735,622(-) T/C upstream_transcript_variant
rs1001507218 -- 93,734,591(-) C/T upstream_transcript_variant
rs1002762038 -- 93,735,501(-) T/C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1304 Gene

Variant ID Type Subtype PubMed ID
esv3627294 CNV gain 21293372
nsv832232 CNV gain 17160897

Additional Variant Information for MIR1304 Gene

Human Gene Mutation Database (HGMD)
MIR1304
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1304

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1304 Gene

Disorders for MIR1304 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1304 Gene - From: HGMD and DISEASES

Disorder Aliases PubMed IDs
hypopharynx cancer
  • hypopharyngeal cancer
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1304

genes like me logo Genes that share disorders with MIR1304: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1304 Gene

Publications for MIR1304 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR1304 Gene

Sources for MIR1304 Gene