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Aliases for MIR1303 Gene

Subcategory (RNA class) for MIR1303 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1303 Gene

  • MicroRNA 1303 2 3 5
  • Hsa-Mir-1303 3
  • MIRN1303 3

External Ids for MIR1303 Gene

Previous HGNC Symbols for MIR1303 Gene

  • MIRN1303

Previous GeneCards Identifiers for MIR1303 Gene

  • GC00U923081
  • GC05P154046

Summaries for MIR1303 Gene

Entrez Gene Summary for MIR1303 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1303 Gene

MIR1303 (MicroRNA 1303) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1303 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1303 Gene

Genomics for MIR1303 Gene

GeneHancer (GH) Regulatory Elements for MIR1303 Gene

Promoters and enhancers for MIR1303 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I154752 Promoter/Enhancer 2 Ensembl ENCODE dbSUPER 11.5 +71.7 71707 9.1 CLOCK MLX DMAP1 YY1 E2F8 ZNF143 ZNF263 SP3 MEF2D ZNF610 SAP30L-AS1 CNOT8 GEMIN5 LARP1 MIR1303 FAM114A2 GC05M154784 GC05P154730
GH05I154646 Enhancer 1.2 Ensembl ENCODE 12.4 -37.7 -37680 2.6 PKNOX1 MLX ARNT ARID4B SIN3A DMAP1 YY1 ZNF766 E2F8 REST MIR1303 GEMIN5 CNOT8 LARP1 GC05P154654 GC05M154594
GH05I154782 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.2 +98.0 98025 2.8 PKNOX1 USF1 ZNF223 EBF1 ZIC2 POLR2A SCRT2 PRDM10 HLF USF2 GC05M154784 CNOT8 LARP1 FAXDC2 MIR1303 GC05P154730
GH05I154792 Enhancer 0.8 ENCODE dbSUPER 11.5 +108.1 108138 3.1 PHF21A GFI1B FEZF1 FOSL1 PRDM6 FOS KDM1A TRIM28 ZXDB MIR1303 LARP1 GC05M154789 PIR54329
GH05I154800 Enhancer 0.8 ENCODE dbSUPER 11.3 +115.0 115020 0.2 GATAD2A SAP130 TEAD1 ARID4B PPARG THRB RARA SKI POLR2A SMAD4 FAXDC2 CNOT8 MIR1303 GC05M154789 PIR54329 LARP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1303 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1303 Gene

Genomic Locations for MIR1303 Gene
chr5:154,685,776-154,685,861
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand
chr5:154,065,336-154,065,421
(GRCh37/hg19)

Genomic View for MIR1303 Gene

Genes around MIR1303 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1303 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1303 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1303 Gene

Proteins for MIR1303 Gene

Post-translational modifications for MIR1303 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1303 Gene

Domains & Families for MIR1303 Gene

Gene Families for MIR1303 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1303: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1303 Gene

Function for MIR1303 Gene

Phenotypes From GWAS Catalog for MIR1303 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1303 Gene

Localization for MIR1303 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1303 Gene

Pathways & Interactions for MIR1303 Gene

SuperPathways for MIR1303 Gene

No Data Available

Interacting Proteins for MIR1303 Gene

Gene Ontology (GO) - Biological Process for MIR1303 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1303 Gene

Drugs & Compounds for MIR1303 Gene

No Compound Related Data Available

Transcripts for MIR1303 Gene

mRNA/cDNA for MIR1303 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1303 Gene

No ASD Table

Relevant External Links for MIR1303 Gene

GeneLoc Exon Structure for
MIR1303
ECgene alternative splicing isoforms for
MIR1303

Expression for MIR1303 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1303 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1303 Gene:

MIR1303
genes like me logo Genes that share expression patterns with MIR1303: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1303 Gene

Orthologs for MIR1303 Gene

Evolution for MIR1303 Gene

ENSEMBL:
Gene Tree for MIR1303 (if available)
TreeFam:
Gene Tree for MIR1303 (if available)

No data available for Orthologs for MIR1303 Gene

Paralogs for MIR1303 Gene

No data available for Paralogs for MIR1303 Gene

Variants for MIR1303 Gene

Sequence variations from dbSNP and Humsavar for MIR1303 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000294224 -- 154,684,681(+) C/A upstream_transcript_variant
rs1002057699 -- 154,684,865(+) G/C upstream_transcript_variant
rs1004135699 -- 154,686,336(+) G/T downstream_transcript_variant
rs1004439002 -- 154,684,281(+) C/G upstream_transcript_variant
rs1005657705 -- 154,685,583(+) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1303 Gene

Variant ID Type Subtype PubMed ID
nsv462491 CNV loss 19166990
nsv600090 CNV loss 21841781

Additional Variant Information for MIR1303 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1303

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1303 Gene

Disorders for MIR1303 Gene

Additional Disease Information for MIR1303

No disorders were found for MIR1303 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1303 Gene

Publications for MIR1303 Gene

  1. miR-1303 promotes the proliferation of neuroblastoma cell SH-SY5Y by targeting GSK3β and SFRP1. (PMID: 27434867) Li Z … Zhou L (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58
  2. Increased serum microRNAs are closely associated with the presence of microvascular complications in type 2 diabetes mellitus. (PMID: 26831044) Wang C … Wang J (Scientific reports 2016) 3 58
  3. miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells. (PMID: 24647998) Zhang SJ … Zhao GQ (Digestive diseases and sciences 2014) 3 58
  4. Differential expression of microRNAs in plasma of patients with laryngeal squamous cell carcinoma: potential early-detection markers for laryngeal squamous cell carcinoma. (PMID: 23817697) Ayaz L … Tamer L (Journal of cancer research and clinical oncology 2013) 3 58
  5. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58

Products for MIR1303 Gene

Sources for MIR1303 Gene

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