Free for academic non-profit institutions. Other users need a Commercial license
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...
Aliases for MIR1301 Gene
Subcategory (RNA class) for MIR1301 Gene
miRNA
Quality Score for this RNA gene is
16
Aliases for MIR1301 Gene
External Ids for MIR1301 Gene
- HGNC: 35253
- Entrez Gene: 100302246
- Ensembl: ENSG00000221445
- miRBase: hsa-mir-1301
Previous HGNC Symbols for MIR1301 Gene
- MIRN1301
Previous GeneCards Identifiers for MIR1301 Gene
- GC00U923084
- GC02M025406
- GC02M025551
Summaries for MIR1301 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR1301 Gene
MIR1301 (MicroRNA 1301) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR1301 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1301 Gene
Genomics for MIR1301 Gene
GeneHancer (GH) Regulatory Elements for MIR1301 Gene
Promoters and enhancers for MIR1301 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J025327 | Enhancer | 0.5 | dbSUPER | 750.6 | -1.9 | -1937 | 5.7 | ZSCAN4 ZKSCAN1 BCOR ZFHX2 ADNP ZMYM3 KDM1A | MIR1301 DTNB lnc-EFR3B-7 DNMT3A | |
| GH02J025272 | Enhancer | 1.4 | FANTOM5 ENCODE CraniofacialAtlas dbSUPER | 12.1 | +51.8 | 51793 | 8.7 | ZNF24 SP1 CTCF NR2F6 ZNF362 MYC ETV6 RELA HLF L3MBTL2 | MIR1301 POMC DNAJC27 piR-43105-342 DNMT3A | |
| GH02J025292 | Enhancer | 1.3 | FANTOM5 ENCODE CraniofacialAtlas dbSUPER | 12.1 | +33.7 | 33677 | 4.3 | ZBTB40 POLR2A MYC MAX NKRF MLLT1 ZNF687 ZBED1 IKZF1 ZIC2 | DNMT3A MIR1301 DNAJC27 piR-43105-342 | |
| GH02J025284 | Enhancer | 1.1 | FANTOM5 ENCODE dbSUPER | 11.7 | +42.6 | 42635 | 2.3 | NR2F1 NR2F6 MYC MAX POLR2A ZNF687 IKZF1 PKNOX1 DPF2 ELF1 | DNMT3A MIR1301 LINC01381 DNAJC27 piR-43105-342 | |
| GH02J025288 | Enhancer | 0.7 | ENCODE dbSUPER | 12.1 | +38.3 | 38299 | 3.2 | HLF NFIB POLR2A RCOR1 NFIC ZFHX2 ZNF48 | MIR1301 LINC01381 POMC piR-43105-342 DNMT3A |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MIR1301 on UCSC Golden Path with GeneCards custom track
Genomic Locations for MIR1301 Gene
Genomic Locations for MIR1301 Gene
- chr2:25,328,640-25,328,721
- (GRCh38/hg38)
- Size:
- 82 bases
- Orientation:
- Minus strand
- chr2:25,551,509-25,551,590
- (GRCh37/hg19)
- Size:
- 82 bases
- Orientation:
- Minus strand
Genomic View for MIR1301 Gene
Genes around MIR1301 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2p23.3 by HGNC
- 2p23.3 by Entrez Gene
- 2p23.3 by Ensembl
MIR1301 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR1301 Gene
Proteins for MIR1301 Gene
Post-translational modifications for MIR1301 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1301
- Origene Custom Protein Services for MIR1301
No data available for DME Specific Peptides for MIR1301 Gene
Domains & Families for MIR1301 Gene
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1301 Gene
Function for MIR1301 Gene
Phenotypes From GWAS Catalog for MIR1301 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Browse CRISPR knockouts for MIR1301
- Applied Biological Materials (abm): CRISPR Clones for MIR1301 - Select products 50% OFF >
- * MIR1301 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MIR1301 CRISPR applications: KO, Activation, Repression, and more - Browse All
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR1301 - Select products 50% OFF >
- * MIR1301 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MIR1301 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1301 Gene
Localization for MIR1301 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | HDA | 26646931 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR1301 Gene
Transcripts for MIR1301 Gene
mRNA/cDNA for MIR1301 Gene
- (1) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000408518 82 bps (ENST00000408518.3)
- (3) RNACentral transcripts :
- (1) LncBase transcripts :
- (4) ENA transcripts :
- (1) TarBase transcripts :
- (3) miRBase transcripts :
CRISPR Products
- Browse CRISPR knockouts for MIR1301
- Applied Biological Materials (abm): CRISPR Clones for MIR1301 - Select products 50% OFF >
- * MIR1301 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MIR1301 CRISPR applications: KO, Activation, Repression, and more - Browse All
miRNA Products
Inhibitory RNA Products
Clone Products
- Applied Biological Materials (abm): Clones for MIR1301 - Select products 50% OFF >
- * MIR1301 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MIR1301 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for MIR1301 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR1301 Gene:
MIR1301Primer Products
-
OriGene qPCR primer pairs for MIR1301
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1301 Gene
Orthologs for MIR1301 Gene
No data available for Orthologs for MIR1301 Gene
Paralogs for MIR1301 Gene
No data available for Paralogs for MIR1301 Gene
Variants for MIR1301 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1001374401 | -- | 25,329,659(-) | C/G | upstream_transcript_variant | |
| rs1001447948 | -- | 25,329,446(-) | G/C | upstream_transcript_variant | |
| rs1001722627 | -- | 25,329,226(-) | G/C | upstream_transcript_variant | |
| rs1003303491 | -- | 25,328,909(-) | T/C | upstream_transcript_variant | |
| rs1003789953 | -- | 25,328,232(-) | C/T | downstream_transcript_variant |
Additional Variant Information for MIR1301 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR1301
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1301 Gene
Disorders for MIR1301 Gene
Additional Disease Information for MIR1301
No disorders were found for MIR1301 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1301 Gene
Publications for MIR1301 Gene
- STAT3-induced upregulation of lncRNA ABHD11-AS1 promotes tumour progression in papillary thyroid carcinoma by regulating miR-1301-3p/STAT3 axis and PI3K/AKT signalling pathway. (PMID: 30657221) Wen J … Zhu Q (Cell proliferation 2019) 3 56
- MicroRNA-1301 inhibits migration and invasion of osteosarcoma cells by targeting BCL9. (PMID: 30172867) Wang L … Chao Y (Gene 2018) 3 56
- EZH2 induces the expression of miR-1301 as a negative feedback control mechanism in triple negative breast cancer. (PMID: 29790898) Wu Q … Feng J (Acta biochimica et biophysica Sinica 2018) 3 56
- miR-1301-3p promotes prostate cancer stem cell expansion by targeting SFRP1 and GSK3β. (PMID: 29358129) Song XL … Zhao SC (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3 56
- MiR-1301-3p inhibits human breast cancer cell proliferation by regulating cell cycle progression and apoptosis through directly targeting ICT1. (PMID: 29951881) Peng X … Shen Y (Breast cancer (Tokyo, Japan) 2018) 3 56
ExternalLinks
Products for MIR1301 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR1301
- Origene Custom Protein Services for MIR1301
- Browse OriGene Inhibitory RNA Products For MIR1301
- OriGene qPCR primer pairs for MIR1301
- Browse CRISPR knockouts for MIR1301
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MIR1301
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for MIR1301
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for MIR1301
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MIR1301
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for MIR1301
Sources for MIR1301 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource