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Aliases for MIR1296 Gene

Subcategory (RNA class) for MIR1296 Gene


Quality Score for this RNA gene is


Aliases for MIR1296 Gene

  • MicroRNA 1296 2 3 5
  • Hsa-Mir-1296 3
  • Mir-1296 3
  • MIRN1296 3

External Ids for MIR1296 Gene

Previous HGNC Symbols for MIR1296 Gene

  • MIRN1296

Previous GeneCards Identifiers for MIR1296 Gene

  • GC00U922842
  • GC10M064803
  • GC10M065132

Summaries for MIR1296 Gene

Entrez Gene Summary for MIR1296 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1296 Gene

MIR1296 (MicroRNA 1296) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1296 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1296 Gene

Genomics for MIR1296 Gene

GeneHancer (GH) Regulatory Elements for MIR1296 Gene

Promoters and enhancers for MIR1296 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I063375 Enhancer 0.4 Ensembl 0.8 -2.7 -2653 0.2 HLF CEBPA GC10M063361 MIR1296 JMJD1C
GH10I063368 Enhancer 0.4 FANTOM5 0.8 +4.0 4040 0.3 ATF4 ZNF366 NRBF2 MIR1296 GC10M063361 ENSG00000270421 JMJD1C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1296 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1296 Gene

Genomic Locations for MIR1296 Gene
92 bases
Minus strand

Genomic View for MIR1296 Gene

Genes around MIR1296 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1296 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1296 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1296 Gene

ORGUL Member Location for MIR1296 Gene

ORGUL Member Location for MIR1296 gene

Proteins for MIR1296 Gene

Post-translational modifications for MIR1296 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1296 Gene

Domains & Families for MIR1296 Gene

Gene Families for MIR1296 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1296: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1296 Gene

Function for MIR1296 Gene

Phenotypes From GWAS Catalog for MIR1296 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1296 Gene

Localization for MIR1296 Gene

Gene Ontology (GO) - Cellular Components for MIR1296 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR1296: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR1296 Gene

Pathways & Interactions for MIR1296 Gene

SuperPathways for MIR1296 Gene

No Data Available

Interacting Proteins for MIR1296 Gene

Gene Ontology (GO) - Biological Process for MIR1296 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1296 Gene

Drugs & Compounds for MIR1296 Gene

No Compound Related Data Available

Transcripts for MIR1296 Gene

mRNA/cDNA for MIR1296 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1296 Gene

No ASD Table

Relevant External Links for MIR1296 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1296 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1296 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1296 Gene:

genes like me logo Genes that share expression patterns with MIR1296: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1296 Gene

Orthologs for MIR1296 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR1296 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1296 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-1296 34
  • 97 (a)
(Canis familiaris)
Mammalia -- 34
  • 97 (a)
Species where no ortholog for MIR1296 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1296 Gene

Gene Tree for MIR1296 (if available)
Gene Tree for MIR1296 (if available)

Paralogs for MIR1296 Gene

No data available for Paralogs for MIR1296 Gene

Variants for MIR1296 Gene

Sequence variations from dbSNP and Humsavar for MIR1296 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1002408128 -- 63,373,610(-) AAA/AA upstream_transcript_variant
rs1003233384 -- 63,373,350(-) C/T upstream_transcript_variant
rs1003456211 -- 63,374,924(-) T/C upstream_transcript_variant
rs1004511613 -- 63,374,244(-) A/G upstream_transcript_variant
rs1005668020 -- 63,374,301(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1296 Gene

Variant ID Type Subtype PubMed ID
esv2677353 CNV deletion 23128226

Additional Variant Information for MIR1296 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1296 Gene

Disorders for MIR1296 Gene

Additional Disease Information for MIR1296

No disorders were found for MIR1296 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1296 Gene

Publications for MIR1296 Gene

  1. miR 1296-5p Inhibits the Migration and Invasion of Gastric Cancer Cells by Repressing ERBB2 Expression. (PMID: 28099468) Shan X … Zhu J (PloS one 2017) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. Tumor suppressor role of microRNA-1296 in triple-negative breast cancer. (PMID: 26799586) Phan B … Dar AA (Oncotarget 2016) 3 58
  4. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method. (PMID: 25201988) Rietveld CA … Koellinger PD (Proceedings of the National Academy of Sciences of the United States of America 2014) 3 58
  5. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58

Products for MIR1296 Gene

Sources for MIR1296 Gene

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