microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1295B Gene

Subcategory (RNA class) for MIR1295B Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR1295B Gene

  • MicroRNA 1295b 2 3 5
  • Hsa-Mir-1295b 2 3
  • MIR1295B 2 5
  • MIMAT0022294 50
  • MIMAT0022293 50
  • MI0019146 50

External Ids for MIR1295B Gene

Previous GeneCards Identifiers for MIR1295B Gene

  • GC01U903329

Summaries for MIR1295B Gene

Entrez Gene Summary for MIR1295B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1295B Gene

MIR1295B (MicroRNA 1295b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1295B Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1295B Gene

Genomics for MIR1295B Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1295B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J171090 Promoter 0.7 EPDnew 0.4 -10.9 -10853 0.1 REST ATF3 YY1 RAD21 HNF4A HNF4G TAF1 SP1 FMO3 MIR1295B FMO2 ENSG00000231424
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1295B on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1295B Gene

Genomic Locations for MIR1295B Gene
chr1:171,101,739-171,101,798
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand

Genomic View for MIR1295B Gene

Genes around MIR1295B on UCSC Golden Path with GeneCards custom track
MIR1295B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1295B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1295B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1295B Gene

Proteins for MIR1295B Gene

Post-translational modifications for MIR1295B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1295B Gene

Domains & Families for MIR1295B Gene

Gene Families for MIR1295B Gene

HGNC:
genes like me logo Genes that share domains with MIR1295B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1295B Gene

Function for MIR1295B Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1295B Gene

Localization for MIR1295B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1295B Gene

Pathways & Interactions for MIR1295B Gene

PathCards logo

SuperPathways for MIR1295B Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1295B Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1295B Gene

Drugs & Compounds for MIR1295B Gene

No Compound Related Data Available

Transcripts for MIR1295B Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1295B Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D4E4_9606 precursor_RNA 60 4

HGNC: 43524,

RefSeq: NR_049854,

Ensembl: ENST00000636144 (view in UCSC) ,

miRBase: MI0019146,

URS000075AF37_9606 miRNA 22 2

RefSeq: NR_049854,

miRBase: MIMAT0022294,

URS000075EE23_9606 miRNA 21 2

RefSeq: NR_049854,

miRBase: MIMAT0022293,

URS00002F1E1B_9606 miRNA 23 1

ENA: AB372579.1:1..23:ncRNA,

URS0000504C6E_9606 miRNA 21 1

ENA: AB372768.1:1..21:ncRNA,

MIR1295B in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1295B Gene

No ASD Table

Relevant External Links for MIR1295B Gene

GeneLoc Exon Structure for
MIR1295B

No data available for mRNA/cDNA for MIR1295B Gene

Expression for MIR1295B Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1295B Gene

Orthologs for MIR1295B Gene

Evolution for MIR1295B Gene

ENSEMBL:
Gene Tree for MIR1295B (if available)
TreeFam:
Gene Tree for MIR1295B (if available)

No data available for Orthologs for MIR1295B Gene

Paralogs for MIR1295B Gene

No data available for Paralogs for MIR1295B Gene

Variants for MIR1295B Gene

Additional dbSNP identifiers (rs#s) for MIR1295B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1295B Gene

Variant ID Type Subtype PubMed ID
esv28731 CNV gain+loss 19812545

Additional Variant Information for MIR1295B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1295B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1295B Gene

Disorders for MIR1295B Gene

Additional Disease Information for MIR1295B

No disorders were found for MIR1295B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1295B Gene

Publications for MIR1295B Gene

  1. Decreased expression of fecal miR-4478 and miR-1295b-3p in early-stage colorectal cancer. (PMID: 25519020) Ghanbari R … Knuutila S (Cancer biomarkers : section A of Disease markers 2015) 3
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1295B Gene

Sources for MIR1295B Gene