microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1293 Gene

Subcategory (RNA class) for MIR1293 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR1293 Gene

  • MicroRNA 1293 2 3 5
  • Hsa-Mir-1293 2 3
  • Hsa-MiR-1293 163 173
  • MIR1293 2 5
  • MIMAT0005883 50
  • MI0006355 50
  • MIRN1293 3
  • Mir-1293 3

External Ids for MIR1293 Gene

Previous HGNC Symbols for MIR1293 Gene

  • MIRN1293

Previous GeneCards Identifiers for MIR1293 Gene

  • GC00U923124
  • GC12M048915
  • GC12M050627

Summaries for MIR1293 Gene

Entrez Gene Summary for MIR1293 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1293 Gene

MIR1293 (MicroRNA 1293) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1293 include Renal Cell Carcinoma, Papillary, 1.

Additional gene information for MIR1293 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1293 Gene

Genomics for MIR1293 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1293 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J050234 Enhancer 0.9 Ensembl ENCODE 600.7 -0.4 -412 1 JUND PHF21A MGA NFE2 GATAD2A JUN MNT MYC EP400 FOSL1 MIR1293 CERS5 SPATS2 ENSG00000257298 RNU6-1093P LIMA1
GH12J050232 Enhancer 0.8 Ensembl ENCODE 600.7 +1.2 1211 1.2 ZIC2 ZNF341 RELB ZBTB17 NBN ZNF189 RCOR1 FEZF1 PRDM6 KDM1A MIR1293 lnc-CERS5-5 LIMA1 CERS5
GH12J050246 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 -19.6 -19643 16.1 CREB1 GATAD2A PRDM10 ZNF629 RFX1 LEF1 SOX13 IKZF1 ZNF692 RCOR2 SMARCD1 CERS5 SPATS2 COX14 LIMA1 SLC11A2 PRPF40B ENSG00000257298 PRPH PARK7P1
GH12J050239 Enhancer 1.1 ENCODE dbSUPER 0.4 -7.4 -7433 4.6 GATAD2A IKZF1 FOXA1 PKNOX1 RXRB REST ZNF24 DPF2 ZNF600 CEBPA CERS5 LIMA1 MIR1293 RNU6-1093P
GH12J050245 Enhancer 0.3 Ensembl dbSUPER 0.4 -11.3 -11289 0.2 RNU6-1093P MIR1293 LIMA1 CERS5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1293 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1293 Gene

Genomic Locations for MIR1293 Gene
chr12:50,234,142-50,234,212
(GRCh38/hg38)
Size:
71 bases
Orientation:
Minus strand
chr12:50,627,925-50,627,995
(GRCh37/hg19)
Size:
71 bases
Orientation:
Minus strand

Genomic View for MIR1293 Gene

Genes around MIR1293 on UCSC Golden Path with GeneCards custom track
MIR1293 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1293 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1293 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1293 Gene

Proteins for MIR1293 Gene

Post-translational modifications for MIR1293 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1293 Gene

Domains & Families for MIR1293 Gene

Gene Families for MIR1293 Gene

HGNC:
genes like me logo Genes that share domains with MIR1293: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1293 Gene

Function for MIR1293 Gene

Phenotypes From GWAS Catalog for MIR1293 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1293 Gene

Localization for MIR1293 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1293 gene
Compartment Confidence
extracellular 1
cytoskeleton 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1293 Gene

Pathways & Interactions for MIR1293 Gene

PathCards logo

SuperPathways for MIR1293 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1293 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1293 Gene

Drugs & Compounds for MIR1293 Gene

No Compound Related Data Available

Transcripts for MIR1293 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1293 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DE57_9606 precursor_RNA 71 5

HGNC: 35286,

RefSeq: NR_031625,

Ensembl: ENST00000408677 (view in UCSC) ,

miRBase: MI0006355,

ENA: LM610118.1:1..71:precursor_RNA,

URS00001DABC0_9606 miRNA 22 5

RefSeq: NR_031625,

LncBase: hsa-miR-1293,

miRBase: MIMAT0005883,

TarBase: hsa-miR-1293,

ENA: LM380682.1:1..22:ncRNA, LM610118.1:10..31:ncRNA,

MIR1293 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1293 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1293 Gene

No ASD Table

Relevant External Links for MIR1293 Gene

GeneLoc Exon Structure for
MIR1293

Expression for MIR1293 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1293

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1293 Gene

Orthologs for MIR1293 Gene

Evolution for MIR1293 Gene

ENSEMBL:
Gene Tree for MIR1293 (if available)
TreeFam:
Gene Tree for MIR1293 (if available)

No data available for Orthologs for MIR1293 Gene

Paralogs for MIR1293 Gene

No data available for Paralogs for MIR1293 Gene

Variants for MIR1293 Gene

Additional dbSNP identifiers (rs#s) for MIR1293 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1293 Gene

Variant ID Type Subtype PubMed ID
esv2761738 CNV gain 21179565

Additional Variant Information for MIR1293 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1293

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1293 Gene

Disorders for MIR1293 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1293 Gene - From: DISEASES

Disorder Aliases PubMed IDs
renal cell carcinoma, papillary, 1
  • rccp1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1293

genes like me logo Genes that share disorders with MIR1293: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1293 Gene

Publications for MIR1293 Gene

  1. hsa-mir-3199-2 and hsa-mir-1293 as Novel Prognostic Biomarkers of Papillary Renal Cell Carcinoma by COX Ratio Risk Regression Model Screening. (PMID: 28338236) Luo W … Wang XX (Journal of cellular biochemistry 2017) 3
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1293 Gene

Sources for MIR1293 Gene