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Aliases for MIR1290 Gene

Subcategory (RNA class) for MIR1290 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1290 Gene

  • MicroRNA 1290 2 3 5
  • Hsa-Mir-1290 3
  • MIRN1290 3

External Ids for MIR1290 Gene

Previous HGNC Symbols for MIR1290 Gene

  • MIRN1290

Previous GeneCards Identifiers for MIR1290 Gene

  • GC00U923065
  • GC01M019097
  • GC01M019223

Summaries for MIR1290 Gene

Entrez Gene Summary for MIR1290 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1290 Gene

MIR1290 (MicroRNA 1290) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1290 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1290 Gene

Genomics for MIR1290 Gene

GeneHancer (GH) Regulatory Elements for MIR1290 Gene

Promoters and enhancers for MIR1290 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I019045 Enhancer 0.8 ENCODE 11.1 -148.6 -148606 0.7 ELF3 FOXA2 RAD21 RARA YY1 SCRT2 ATF7 THAP11 HMG20B RXRA MIR1290 ALDH4A1 EMC1 LOC105376815 GC01P019027
GH01I018989 Enhancer 0.8 ENCODE 10.4 -91.9 -91894 0.1 ELF3 FOXA2 MLX ARID4B RAD21 RARA ZNF766 MIXL1 HMG20B SP5 IFFO2 ALDH4A1 MIR1290 GC01P019006 LOC105376815
GH01I018972 Enhancer 0.6 ENCODE 11.3 -75.6 -75554 0.1 CTCF NFIB ZMYM3 RAD21 GATA3 NFIC CREB1 ZFP36 HNF4A ZNF444 ALDH4A1 MIR1290 TAS1R2 EMC1 IFFO2 GC01P019006 LOC105376815
GH01I019021 Enhancer 0.2 dbSUPER 10.9 -125.1 -125091 0.6 MIR1290 ALDH4A1 TAS1R2 GC01P019027 GC01P019006 LOC105376815
GH01I018900 Enhancer 0.9 Ensembl 0.8 -3.4 -3429 0.6 FOXA2 MLX ZFP64 ARID4B ZNF48 YY1 SLC30A9 RXRA SP5 MIER2 ALDH4A1 MIR1290 ENSG00000255275
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1290 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1290 Gene

Genomic Locations for MIR1290 Gene
chr1:18,897,071-18,897,148
(GRCh38/hg38)
Size:
78 bases
Orientation:
Minus strand
chr1:19,223,565-19,223,642
(GRCh37/hg19)

Genomic View for MIR1290 Gene

Genes around MIR1290 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1290 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1290 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1290 Gene

Proteins for MIR1290 Gene

Post-translational modifications for MIR1290 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1290 Gene

Domains & Families for MIR1290 Gene

Gene Families for MIR1290 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1290: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1290 Gene

Function for MIR1290 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1290 Gene

Localization for MIR1290 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1290 Gene

Pathways & Interactions for MIR1290 Gene

SuperPathways for MIR1290 Gene

No Data Available

Interacting Proteins for MIR1290 Gene

Gene Ontology (GO) - Biological Process for MIR1290 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008284 positive regulation of cell proliferation IDA 23697990
GO:0030335 positive regulation of cell migration IDA 23697990
genes like me logo Genes that share ontologies with MIR1290: view

No data available for Pathways by source and SIGNOR curated interactions for MIR1290 Gene

Drugs & Compounds for MIR1290 Gene

No Compound Related Data Available

Transcripts for MIR1290 Gene

mRNA/cDNA for MIR1290 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1290 Gene

No ASD Table

Relevant External Links for MIR1290 Gene

GeneLoc Exon Structure for
MIR1290
ECgene alternative splicing isoforms for
MIR1290

Expression for MIR1290 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1290 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1290 Gene:

MIR1290
genes like me logo Genes that share expression patterns with MIR1290: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1290 Gene

Orthologs for MIR1290 Gene

Evolution for MIR1290 Gene

ENSEMBL:
Gene Tree for MIR1290 (if available)
TreeFam:
Gene Tree for MIR1290 (if available)

No data available for Orthologs for MIR1290 Gene

Paralogs for MIR1290 Gene

No data available for Paralogs for MIR1290 Gene

Variants for MIR1290 Gene

Sequence variations from dbSNP and Humsavar for MIR1290 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001453890 -- 18,896,747(-) G/A downstream_transcript_variant
rs1003511829 -- 18,897,605(-) C/T upstream_transcript_variant
rs1004011744 -- 18,898,023(-) C/A upstream_transcript_variant
rs1004196082 -- 18,897,957(-) GGGG/GGG upstream_transcript_variant
rs1004942617 -- 18,898,141(-) C/T upstream_transcript_variant

Additional Variant Information for MIR1290 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1290

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1290 Gene

Disorders for MIR1290 Gene

Additional Disease Information for MIR1290

No disorders were found for MIR1290 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1290 Gene

Publications for MIR1290 Gene

  1. Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer. (PMID: 26711929) Kim G … Jeong HC (Lung cancer (Amsterdam, Netherlands) 2016) 3 58
  2. Circulating microRNA-1290 as a novel diagnostic and prognostic biomarker in human colorectal cancer. (PMID: 27502702) Imaoka H … Kusunoki M (Annals of oncology : official journal of the European Society for Medical Oncology 2016) 3 58
  3. Global miRNA Expression Profiling Identifies miR-1290 as Novel Potential oncomiR in Laryngeal Carcinoma. (PMID: 26694163) Janiszewska J … Jarmuz-Szymczak M (PloS one 2015) 3 58
  4. MiR-1290 promotes cancer progression by targeting nuclear factor I/X(NFIX) in esophageal squamous cell carcinoma (ESCC). (PMID: 26653554) Mao Y … Li B (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015) 3 58
  5. Two cellular microRNAs, miR-196b and miR-1290, contribute to HIV-1 latency. (PMID: 26469550) Wang P … Zhu H (Virology 2015) 3 58

Products for MIR1290 Gene

Sources for MIR1290 Gene

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