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Aliases for MIR1289-2 Gene

Subcategory (RNA class) for MIR1289-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR1289-2 Gene

  • MicroRNA 1289-2 2 3 5
  • Hsa-Mir-1289-2 3
  • MIRN1289-2 3

External Ids for MIR1289-2 Gene

Previous HGNC Symbols for MIR1289-2 Gene

  • MIRN1289-2

Previous GeneCards Identifiers for MIR1289-2 Gene

  • GC00U923069
  • GC05M132792
  • GC05M132763

Summaries for MIR1289-2 Gene

Entrez Gene Summary for MIR1289-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1289-2 Gene

MIR1289-2 (MicroRNA 1289-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1289-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1289-2 Gene

Genomics for MIR1289-2 Gene

GeneHancer (GH) Regulatory Elements for MIR1289-2 Gene

Promoters and enhancers for MIR1289-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I133244 Enhancer 1.4 FANTOM5 Ensembl ENCODE 9.7 +182.0 182048 3.2 ATF1 PKNOX1 FOXA2 ZFP64 SIN3A GLIS2 ATF7 FOS RUNX3 JUNB ENSG00000249478 MIR1289-2 SOWAHA ENSG00000250244 FSTL4
GH05I133456 Enhancer 0.9 Ensembl ENCODE 12 -29.3 -29269 1.9 FOXA2 NFIB MAX CEBPG RAD21 YY1 GATA3 RCOR1 ZNF687 TFE3 ENSG00000280104 MIR1289-2 ENSG00000270177 FSTL4
GH05I133247 Enhancer 1.1 Ensembl ENCODE 9.7 +177.3 177325 5.6 ARNT ARID2 ZNF143 FOS ATF7 NCOA1 REST ZNF518A ZNF592 MEF2D MIR1289-2 AFF4 ENSG00000249478 ENSG00000250244 FSTL4
GH05I133466 Enhancer 0.8 ENCODE 11.3 -39.9 -39939 2.1 ZSCAN5A HDGF ZNF473 SUZ12 ZNF493 ZSCAN4 ZNF266 KLF17 PLRG1 MCM2 AFF4 ENSG00000202533 LOC105379175 IL4 MIR1289-2 RAD50 ZCCHC10 ENSG00000280104 PIR50619 FSTL4
GH05I133941 Enhancer 0.8 ENCODE dbSUPER 9.8 -513.8 -513810 0.9 GATAD2A L3MBTL2 NR4A1 CBFA2T3 DPF2 CDC5L MITF RAD51 SMARCA4 HDAC2 MIR1289-2 LOC105379182 WSPAR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1289-2 Gene

Genomic Locations for MIR1289-2 Gene
chr5:133,427,596-133,427,706
(GRCh38/hg38)
Size:
111 bases
Orientation:
Minus strand
chr5:132,763,288-132,763,398
(GRCh37/hg19)

Genomic View for MIR1289-2 Gene

Genes around MIR1289-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1289-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1289-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 Gene

ORGUL Member Location for MIR1289-2 gene

Proteins for MIR1289-2 Gene

Post-translational modifications for MIR1289-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1289-2 Gene

Domains & Families for MIR1289-2 Gene

Gene Families for MIR1289-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1289-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1289-2 Gene

Function for MIR1289-2 Gene

Phenotypes From GWAS Catalog for MIR1289-2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1289-2 Gene

Localization for MIR1289-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1289-2 Gene

Pathways & Interactions for MIR1289-2 Gene

SuperPathways for MIR1289-2 Gene

No Data Available

Interacting Proteins for MIR1289-2 Gene

Gene Ontology (GO) - Biological Process for MIR1289-2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1289-2 Gene

Drugs & Compounds for MIR1289-2 Gene

No Compound Related Data Available

Transcripts for MIR1289-2 Gene

mRNA/cDNA for MIR1289-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1289-2 Gene

No ASD Table

Relevant External Links for MIR1289-2 Gene

GeneLoc Exon Structure for
MIR1289-2
ECgene alternative splicing isoforms for
MIR1289-2

Expression for MIR1289-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1289-2 Gene

genes like me logo Genes that share expression patterns with MIR1289-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1289-2 Gene

Orthologs for MIR1289-2 Gene

Evolution for MIR1289-2 Gene

ENSEMBL:
Gene Tree for MIR1289-2 (if available)
TreeFam:
Gene Tree for MIR1289-2 (if available)

No data available for Orthologs for MIR1289-2 Gene

Paralogs for MIR1289-2 Gene

No data available for Paralogs for MIR1289-2 Gene

Variants for MIR1289-2 Gene

Sequence variations from dbSNP and Humsavar for MIR1289-2 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1001671885 -- 133,428,565(-) G/A upstream_transcript_variant
rs1001685564 -- 133,428,275(-) C/T upstream_transcript_variant
rs1002125560 -- 133,428,843(-) T/C upstream_transcript_variant
rs1003456331 -- 133,428,080(-) A/C upstream_transcript_variant
rs10060919 -- 133,428,025(-) G/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1289-2 Gene

Variant ID Type Subtype PubMed ID
nsv599716 CNV gain 21841781

Additional Variant Information for MIR1289-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1289-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1289-2 Gene

Disorders for MIR1289-2 Gene

Additional Disease Information for MIR1289-2

No disorders were found for MIR1289-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1289-2 Gene

Publications for MIR1289-2 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1289-2 Gene

Sources for MIR1289-2 Gene

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