microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1288 Gene

Subcategory (RNA class) for MIR1288 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR1288 Gene

  • MicroRNA 1288 2 3 5
  • Hsa-Mir-1288 2 3
  • MIR1288 2 5
  • Hsa-MiR-1288-3p 173
  • MIMAT0026743 50
  • MIMAT0005942 50
  • MI0006432 50
  • MIRN1288 3

External Ids for MIR1288 Gene

Previous HGNC Symbols for MIR1288 Gene

  • MIRN1288

Previous GeneCards Identifiers for MIR1288 Gene

  • GC00U922987
  • GC17P016127
  • GC17P016185

Summaries for MIR1288 Gene

Entrez Gene Summary for MIR1288 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1288 Gene

MIR1288 (MicroRNA 1288) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1288 include Bleeding Disorder, Platelet-Type, 9 and Salpingitis.

Additional gene information for MIR1288 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1288 Gene

Genomics for MIR1288 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1288 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1288 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1288 Gene

Genomic Locations for MIR1288 Gene
chr17:16,282,014-16,282,088
(GRCh38/hg38)
Size:
75 bases
Orientation:
Plus strand
chr17:16,185,328-16,185,402
(GRCh37/hg19)
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR1288 Gene

Genes around MIR1288 on UCSC Golden Path with GeneCards custom track
MIR1288 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1288 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1288 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1288 Gene

Proteins for MIR1288 Gene

Post-translational modifications for MIR1288 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1288 Gene

Domains & Families for MIR1288 Gene

Gene Families for MIR1288 Gene

HGNC:
genes like me logo Genes that share domains with MIR1288: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1288 Gene

Function for MIR1288 Gene

Phenotypes From GWAS Catalog for MIR1288 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1288 Gene

Localization for MIR1288 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1288 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1288 Gene

Pathways & Interactions for MIR1288 Gene

PathCards logo

SuperPathways for MIR1288 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1288 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1288 Gene

Drugs & Compounds for MIR1288 Gene

No Compound Related Data Available

Transcripts for MIR1288 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1288 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C2CE_9606 precursor_RNA 75 4

HGNC: 35363,

RefSeq: NR_031698,

Ensembl: ENST00000408428 (view in UCSC) ,

miRBase: MI0006432,

URS000075CAED_9606 miRNA 21 3

RefSeq: NR_031698,

miRBase: MIMAT0005942,

TarBase: hsa-miR-1288-3p,

URS00008E39F4_9606 miRNA 23 2

RefSeq: NR_031698,

miRBase: MIMAT0026743,

MIR1288 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1288 Gene

No ASD Table

Relevant External Links for MIR1288 Gene

GeneLoc Exon Structure for
MIR1288

No data available for mRNA/cDNA for MIR1288 Gene

Expression for MIR1288 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1288

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1288 Gene

Orthologs for MIR1288 Gene

Evolution for MIR1288 Gene

ENSEMBL:
Gene Tree for MIR1288 (if available)
TreeFam:
Gene Tree for MIR1288 (if available)

No data available for Orthologs for MIR1288 Gene

Paralogs for MIR1288 Gene

No data available for Paralogs for MIR1288 Gene

Variants for MIR1288 Gene

Additional dbSNP identifiers (rs#s) for MIR1288 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1288 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV deletion 23290073
nsv1063764 CNV loss 25217958
nsv528263 CNV loss 19592680

Additional Variant Information for MIR1288 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1288

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1288 Gene

Disorders for MIR1288 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR1288 Gene - From: DISEASES

Disorder Aliases PubMed IDs
bleeding disorder, platelet-type, 9
  • bdplt9
salpingitis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1288

genes like me logo Genes that share disorders with MIR1288: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1288 Gene

Publications for MIR1288 Gene

  1. Rs7219 Regulates the Expression of GRB2 by Affecting miR-1288-Mediated Inhibition and Contributes to the Risk of Schizophrenia in the Chinese Han Population. (PMID: 30474799) Yang J … Su L (Cellular and molecular neurobiology 2019) 3
  2. MicroRNA‑1288 promotes cell proliferation of human glioblastoma cells by repressing ubiquitin carboxyl‑terminal hydrolase CYLD expression. (PMID: 28901464) Yin J … Feng M (Molecular medicine reports 2017) 3
  3. Overexpression of microRNA-1288 in oesophageal squamous cell carcinoma. (PMID: 27658568) Gopalan V … Lam AK (Experimental cell research 2016) 3
  4. Regulation of microRNA-1288 in colorectal cancer: altered expression and its clinicopathological significance. (PMID: 24009195) Gopalan V … Lam AK (Molecular carcinogenesis 2014) 3
  5. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3

Products for MIR1288 Gene

Sources for MIR1288 Gene