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Aliases for MIR1288 Gene

Subcategory (RNA class) for MIR1288 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1288 Gene

  • MicroRNA 1288 2 3 5
  • Hsa-Mir-1288 3
  • MIRN1288 3

External Ids for MIR1288 Gene

Previous HGNC Symbols for MIR1288 Gene

  • MIRN1288

Previous GeneCards Identifiers for MIR1288 Gene

  • GC00U922987
  • GC17P016127
  • GC17P016185

Summaries for MIR1288 Gene

Entrez Gene Summary for MIR1288 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1288 Gene

MIR1288 (MicroRNA 1288) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1288 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1288 Gene

Genomics for MIR1288 Gene

GeneHancer (GH) Regulatory Elements for MIR1288 Gene

Promoters and enhancers for MIR1288 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I016280 Enhancer 0.8 Ensembl ENCODE 550.8 +0.2 197 2.4 JUN SP1 FOSL1 JUND POLR2A ZNF239 BCL6B FOS FOSL2 MIR1288 ZSWIM7 GC17M016316 PIGL
GH17I016245 Enhancer 1.2 Ensembl ENCODE dbSUPER 12.4 -33.1 -33060 5.9 RAD21 ZSCAN9 ZNF121 THAP11 MIXL1 KLF11 RXRA CEBPB PPARG KAT8 GC17M016250 ZSWIM7 NCOR1 PIGL MIR1288 RNU6-314P ADORA2B TTC19 GC17M016251
GH17I016312 Enhancer 1.2 ENCODE dbSUPER 11.5 +31.7 31702 1.6 PKNOX1 ATF1 FOXA2 ARNT ARID4B FEZF1 DMAP1 ETS1 YY1 TCF12 ZSWIM7 CENPV MIR1288 LRRC75A-AS1 LRRC75A TTC19 GC17M016316 PIGL
GH17I016254 Enhancer 1 Ensembl ENCODE dbSUPER 12.4 -25.9 -25940 3.3 STAT1 RXRA REST RAD21 YY1 FOXA1 JUND HNF4G BCL6 ZBTB33 GC17P016256 ZSWIM7 MIR1288 NCOR1 RNU6-314P PIGL ADORA2B TTC19 GC17M016251
GH17I016242 Enhancer 0.9 ENCODE dbSUPER 12.3 -38.3 -38308 1.7 CEBPG PYGO2 ZBTB40 RELA IRF9 GATA3 ZNF639 PHF21A CAVIN1 ZNF740 ZSWIM7 PIGL NCOR1 ENSG00000266538 TVP23C PPIAP53 MIR1288 LOC644422 MPRIP-AS1 TTC19
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1288 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1288 Gene

Genomic Locations for MIR1288 Gene
chr17:16,282,014-16,282,088
(GRCh38/hg38)
Size:
75 bases
Orientation:
Plus strand
chr17:16,185,328-16,185,402
(GRCh37/hg19)

Genomic View for MIR1288 Gene

Genes around MIR1288 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1288 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1288 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1288 Gene

Proteins for MIR1288 Gene

Post-translational modifications for MIR1288 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1288 Gene

Domains & Families for MIR1288 Gene

Gene Families for MIR1288 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1288: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1288 Gene

Function for MIR1288 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1288 Gene

Localization for MIR1288 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1288 Gene

Pathways & Interactions for MIR1288 Gene

SuperPathways for MIR1288 Gene

No Data Available

Interacting Proteins for MIR1288 Gene

Gene Ontology (GO) - Biological Process for MIR1288 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1288 Gene

Drugs & Compounds for MIR1288 Gene

No Compound Related Data Available

Transcripts for MIR1288 Gene

mRNA/cDNA for MIR1288 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1288 Gene

No ASD Table

Relevant External Links for MIR1288 Gene

GeneLoc Exon Structure for
MIR1288
ECgene alternative splicing isoforms for
MIR1288

Expression for MIR1288 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1288 Gene:

MIR1288
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1288 Gene

Orthologs for MIR1288 Gene

Evolution for MIR1288 Gene

ENSEMBL:
Gene Tree for MIR1288 (if available)
TreeFam:
Gene Tree for MIR1288 (if available)

No data available for Orthologs for MIR1288 Gene

Paralogs for MIR1288 Gene

No data available for Paralogs for MIR1288 Gene

Variants for MIR1288 Gene

Sequence variations from dbSNP and Humsavar for MIR1288 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000984094 -- 16,280,036(+) A/G upstream_transcript_variant
rs1004024355 -- 16,281,313(+) T/C upstream_transcript_variant
rs1005123595 -- 16,280,740(+) C/G upstream_transcript_variant
rs1006378364 -- 16,280,672(+) A/G upstream_transcript_variant
rs1006895195 -- 16,280,886(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1288 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV deletion 23290073
nsv1063764 CNV loss 25217958
nsv528263 CNV loss 19592680

Additional Variant Information for MIR1288 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1288

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1288 Gene

Disorders for MIR1288 Gene

Additional Disease Information for MIR1288

No disorders were found for MIR1288 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1288 Gene

Publications for MIR1288 Gene

  1. Overexpression of microRNA-1288 in oesophageal squamous cell carcinoma. (PMID: 27658568) Gopalan V … Lam AK (Experimental cell research 2016) 3 58
  2. Regulation of microRNA-1288 in colorectal cancer: altered expression and its clinicopathological significance. (PMID: 24009195) Gopalan V … Lam AK (Molecular carcinogenesis 2014) 3 58
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1288 Gene

Sources for MIR1288 Gene

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