microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR1286 Gene

Subcategory (RNA class) for MIR1286 Gene

miRNA

Number of RNA Genes sources:

4 / 17

Aliases for MIR1286 Gene

  • MicroRNA 1286 2 3 5
  • Hsa-Mir-1286 2 3 178
  • MIR1286 2 5
  • MIMAT0005877 50
  • Hsa-MiR-1286 173
  • MI0006348 50
  • MIRN1286 3
  • Mir-1286 3

External Ids for MIR1286 Gene

Previous HGNC Symbols for MIR1286 Gene

  • MIRN1286

Previous GeneCards Identifiers for MIR1286 Gene

  • GC00U923144
  • GC22M018617
  • GC22M020236

Summaries for MIR1286 Gene

Entrez Gene Summary for MIR1286 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1286 Gene

MIR1286 (MicroRNA 1286) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1286 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR1286 Gene

Genomics for MIR1286 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR1286 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR1286 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR1286 Gene

Genomic Locations for MIR1286 Gene
chr22:20,249,134-20,249,211
(GRCh38/hg38)
Size:
78 bases
Orientation:
Minus strand
chr22:20,236,657-20,236,734
(GRCh37/hg19)
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR1286 Gene

Genes around MIR1286 on UCSC Golden Path with GeneCards custom track
MIR1286 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR1286 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1286 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1286 Gene

Proteins for MIR1286 Gene

Post-translational modifications for MIR1286 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1286 Gene

Domains & Families for MIR1286 Gene

Gene Families for MIR1286 Gene

HGNC:
genes like me logo Genes that share domains with MIR1286: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR1286 Gene

Function for MIR1286 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1286 Gene

Localization for MIR1286 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR1286 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1286 Gene

Pathways & Interactions for MIR1286 Gene

PathCards logo

SuperPathways for MIR1286 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR1286 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR1286 Gene

Drugs & Compounds for MIR1286 Gene

No Compound Related Data Available

Transcripts for MIR1286 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR1286 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C8A9_9606 precursor_RNA 78 5

HGNC: 35279,

RefSeq: NR_031618,

Ensembl: ENST00000408112 (view in UCSC) ,

miRBase: MI0006348,

ENA: LM610113.1:1..78:precursor_RNA,

URS00002EF20A_9606 miRNA 21 5

RefSeq: NR_031618,

miRBase: MIMAT0005877,

MirGeneDB: Hsa-Mir-1286_3p,

TarBase: hsa-miR-1286,

ENA: LM380677.1:1..21:ncRNA, LM610113.1:47..67:ncRNA,

URS0000EFC4E2_9606 precursor_RNA 57 1

MirGeneDB: Hsa-Mir-1286,

URS0000EFDDED_9606 miRNA 21 1

MirGeneDB: Hsa-Mir-1286_5p,

MIR1286 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR1286 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1286 Gene

No ASD Table

Relevant External Links for MIR1286 Gene

GeneLoc Exon Structure for
MIR1286

Expression for MIR1286 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR1286 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR1286

genes like me logo Genes that share expression patterns with MIR1286: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1286 Gene

Orthologs for MIR1286 Gene

Evolution for MIR1286 Gene

ENSEMBL:
Gene Tree for MIR1286 (if available)
TreeFam:
Gene Tree for MIR1286 (if available)

No data available for Orthologs for MIR1286 Gene

Paralogs for MIR1286 Gene

No data available for Paralogs for MIR1286 Gene

Variants for MIR1286 Gene

Additional dbSNP identifiers (rs#s) for MIR1286 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR1286 Gene

Variant ID Type Subtype PubMed ID
dgv4480n100 CNV gain 25217958
dgv4481n100 CNV gain 25217958
dgv4482n100 CNV gain 25217958
dgv726n67 CNV gain 20364138
dgv7983n54 CNV gain 21841781
esv2758825 CNV loss 17122850
esv3893434 CNV gain 25118596
esv3893435 CNV gain 25118596
nsv471183 CNV loss 18288195
nsv828938 CNV gain 20364138
nsv828939 CNV loss 20364138
nsv834134 CNV loss 17160897
nsv953027 CNV deletion 24416366

Additional Variant Information for MIR1286 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1286

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR1286 Gene

Disorders for MIR1286 Gene

Additional Disease Information for MIR1286

No disorders were found for MIR1286 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1286 Gene

Publications for MIR1286 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR1286 Gene

Sources for MIR1286 Gene