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Aliases for MIR1278 Gene

Subcategory (RNA class) for MIR1278 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1278 Gene

  • MicroRNA 1278 2 3 5
  • Hsa-Mir-1278 3
  • Mir-1278 3
  • MIRN1278 3

External Ids for MIR1278 Gene

Previous HGNC Symbols for MIR1278 Gene

  • MIRN1278

Previous GeneCards Identifiers for MIR1278 Gene

  • GC00U922953
  • GC01P191373

Summaries for MIR1278 Gene

Entrez Gene Summary for MIR1278 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1278 Gene

MIR1278 (MicroRNA 1278) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1278 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1278 Gene

Genomics for MIR1278 Gene

GeneHancer (GH) Regulatory Elements for MIR1278 Gene

Promoters and enhancers for MIR1278 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I193183 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.6 +50.3 50304 7.4 PKNOX1 ATF1 RAD21 RFX5 ZNF138 ZNF143 ATF7 SMARCA5 ZNF654 NFIL3 B3GALT2 CDC73 MIR1278 UCHL5 ENSG00000276735
GH01I193069 Enhancer 1 ENCODE dbSUPER 10.4 -65.8 -65765 1.8 HDGF PKNOX1 TAF9B FEZF1 ZNF2 RAD21 ZBTB40 CHAMP1 ZNF143 IKZF2 CDC73 GLRX2 MIR1278 UCHL5 TROVE2 ENSG00000272579
GH01I193067 Enhancer 0.8 dbSUPER 10.6 -68.3 -68334 1.5 HDAC1 ATF1 ARNT TCF12 CREM NCOA1 USF2 ZNF592 NFIC SMARCA4 CDC73 MIR1278 B3GALT2 UCHL5 TROVE2 ENSG00000272579
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1278 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1278 Gene

Genomic Locations for MIR1278 Gene
chr1:193,136,503-193,136,583
(GRCh38/hg38)
Size:
81 bases
Orientation:
Plus strand
chr1:193,105,633-193,105,713
(GRCh37/hg19)

Genomic View for MIR1278 Gene

Genes around MIR1278 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1278 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1278 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1278 Gene

Proteins for MIR1278 Gene

Post-translational modifications for MIR1278 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1278 Gene

Domains & Families for MIR1278 Gene

Gene Families for MIR1278 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1278: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1278 Gene

Function for MIR1278 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1278 Gene

Localization for MIR1278 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1278 Gene

Pathways & Interactions for MIR1278 Gene

SuperPathways for MIR1278 Gene

No Data Available

Interacting Proteins for MIR1278 Gene

Gene Ontology (GO) - Biological Process for MIR1278 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1278 Gene

Drugs & Compounds for MIR1278 Gene

No Compound Related Data Available

Transcripts for MIR1278 Gene

mRNA/cDNA for MIR1278 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1278 Gene

No ASD Table

Relevant External Links for MIR1278 Gene

GeneLoc Exon Structure for
MIR1278
ECgene alternative splicing isoforms for
MIR1278

Expression for MIR1278 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1278 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1278 Gene:

MIR1278
genes like me logo Genes that share expression patterns with MIR1278: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1278 Gene

Orthologs for MIR1278 Gene

Evolution for MIR1278 Gene

ENSEMBL:
Gene Tree for MIR1278 (if available)
TreeFam:
Gene Tree for MIR1278 (if available)

No data available for Orthologs for MIR1278 Gene

Paralogs for MIR1278 Gene

No data available for Paralogs for MIR1278 Gene

Variants for MIR1278 Gene

Sequence variations from dbSNP and Humsavar for MIR1278 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1060500024 uncertain-significance, Parathyroid carcinoma 193,135,531(+) T/A upstream_transcript_variant
rs374021222 likely-benign, Parathyroid carcinoma 193,135,533(+) A/G upstream_transcript_variant
rs374834265 likely-benign, Parathyroid carcinoma 193,135,416(+) C/T upstream_transcript_variant
rs746368285 likely-benign, Parathyroid carcinoma 193,135,538(+) C/G upstream_transcript_variant
rs757680253 likely-benign, Parathyroid carcinoma 193,135,530(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1278 Gene

Variant ID Type Subtype PubMed ID
nsv466994 CNV loss 19166990
nsv548658 CNV loss 21841781

Additional Variant Information for MIR1278 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1278

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1278 Gene

Disorders for MIR1278 Gene

Additional Disease Information for MIR1278

No disorders were found for MIR1278 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1278 Gene

Publications for MIR1278 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1278 Gene

Sources for MIR1278 Gene

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