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Aliases for MIR1273D Gene

Subcategory (RNA class) for MIR1273D Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1273D Gene

  • MicroRNA 1273d 2 3 5
  • Hsa-Mir-1273d 3

External Ids for MIR1273D Gene

Previous GeneCards Identifiers for MIR1273D Gene

  • GC01U902997
  • GC14M028344
  • GC14M048227

Summaries for MIR1273D Gene

Entrez Gene Summary for MIR1273D Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1273D Gene

MIR1273D (MicroRNA 1273d) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR1273D include Tooth Agenesis.

Additional gene information for MIR1273D Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1273D Gene

Genomics for MIR1273D Gene

GeneHancer (GH) Regulatory Elements for MIR1273D Gene

Promoters and enhancers for MIR1273D Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I010208 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 -16.5 -16522 6 FOXA2 PKNOX1 SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ZBTB7B KIF1B PGD LZIC RNU6-37P RBP7 MIR1273D
GH01I010230 Enhancer 0.5 ENCODE 0.8 +3.2 3170 0.2 FOSL1 JUND JUN FOS ZBTB33 RNU6-828P KIF1B MIR1273D GC01M010233
GH01I010218 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -9.3 -9291 0.9 ZNF384 EBF1 DPF2 BATF SCRT2 IKZF1 PRDM10 PRDM4 WT1 RUNX3 RNU6-828P DFFA PEX14 KIF1B MIR1273D
GH01I010215 Enhancer 0.9 Ensembl dbSUPER 0.4 -11.5 -11517 1.2 ZNF362 FOXA2 ZNF189 ZNF384 FEZF1 ZNF507 ZNF217 ZNF664 PRDM6 ZNF213 KIF1B MIR1273D
GH01I010236 Enhancer 0.3 ENCODE 0.4 +9.3 9280 0.2 IKZF2 GC01M010233 RNU6-828P UBE4B MIR1273D KIF1B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1273D on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1273D Gene

Genomic Locations for MIR1273D Gene
chr1:10,227,718-10,227,803
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand
chr1:10,287,776-10,287,861
(GRCh37/hg19)

Genomic View for MIR1273D Gene

Genes around MIR1273D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1273D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1273D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1273D Gene

Proteins for MIR1273D Gene

Post-translational modifications for MIR1273D Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1273D Gene

Domains & Families for MIR1273D Gene

Gene Families for MIR1273D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1273D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1273D Gene

Function for MIR1273D Gene

Phenotypes From GWAS Catalog for MIR1273D Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1273D Gene

Localization for MIR1273D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1273D Gene

Pathways & Interactions for MIR1273D Gene

SuperPathways for MIR1273D Gene

No Data Available

Interacting Proteins for MIR1273D Gene

Gene Ontology (GO) - Biological Process for MIR1273D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1273D Gene

Drugs & Compounds for MIR1273D Gene

No Compound Related Data Available

Transcripts for MIR1273D Gene

mRNA/cDNA for MIR1273D Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1273D Gene

No ASD Table

Relevant External Links for MIR1273D Gene

GeneLoc Exon Structure for
MIR1273D
ECgene alternative splicing isoforms for
MIR1273D

Expression for MIR1273D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1273D Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1273D Gene:

MIR1273D
genes like me logo Genes that share expression patterns with MIR1273D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1273D Gene

Orthologs for MIR1273D Gene

Evolution for MIR1273D Gene

ENSEMBL:
Gene Tree for MIR1273D (if available)
TreeFam:
Gene Tree for MIR1273D (if available)

No data available for Orthologs for MIR1273D Gene

Paralogs for MIR1273D Gene

No data available for Paralogs for MIR1273D Gene

Variants for MIR1273D Gene

Sequence variations from dbSNP and Humsavar for MIR1273D Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000974983 -- 10,226,602(+) C/T upstream_transcript_variant
rs1002147611 -- 10,226,269(+) G/T upstream_transcript_variant
rs1003435746 -- 10,227,701(+) G/A/T upstream_transcript_variant
rs1005085428 -- 10,227,470(+) T/C upstream_transcript_variant
rs1005505370 -- 10,225,764(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1273D Gene

Variant ID Type Subtype PubMed ID
esv2758920 CNV gain+loss 17122850

Additional Variant Information for MIR1273D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1273D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1273D Gene

Disorders for MIR1273D Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR1273D Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
tooth agenesis
  • familial tooth agenesis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR1273D

genes like me logo Genes that share disorders with MIR1273D: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR1273D Gene

Publications for MIR1273D Gene

  1. Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis. (PMID: 27362534) Lu Y … Wang L (PloS one 2016) 58
  2. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 58

Products for MIR1273D Gene

Sources for MIR1273D Gene

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