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Aliases for MIR1273A Gene

Subcategory (RNA class) for MIR1273A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1273A Gene

  • MicroRNA 1273a 2 3 5
  • MicroRNA 1273 2 3
  • Hsa-Mir-1273a 3
  • Hsa-Mir-1273 3
  • MIRN1273 3
  • MIR1273 3

External Ids for MIR1273A Gene

Previous HGNC Symbols for MIR1273A Gene

  • MIRN1273
  • MIR1273

Previous GeneCards Identifiers for MIR1273A Gene

  • GC08M101036

Summaries for MIR1273A Gene

Entrez Gene Summary for MIR1273A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1273A Gene

MIR1273A (MicroRNA 1273a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1273A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1273A Gene

Genomics for MIR1273A Gene

GeneHancer (GH) Regulatory Elements for MIR1273A Gene

Promoters and enhancers for MIR1273A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I100027 Enhancer 0.6 ENCODE 550.8 -1.2 -1164 0.2 ZBTB11 ZFP64 INSM2 ZC3H11A ZBTB8A ZNF623 ZNF781 PRDM12 SCRT2 ZNF600 MIR1273A PIR62937 RGS22
GH08I100025 Enhancer 0.4 ENCODE 550.8 -1.9 -1929 0.6 FOXA2 GLIS1 MAFK MIR1273A PIR62937 RGS22
GH08I099903 Enhancer 0.8 ENCODE 10.1 +119.1 119096 2.2 PKNOX1 CLOCK NFIB NEUROD1 NFXL1 ZBTB40 RFX5 FOS HCFC1 GATAD2B RGS22 MIR1273A VPS13B COX6C PIR32500
GH08I100019 Enhancer 0.6 ENCODE 0.8 +4.7 4656 0.2 SMARCA5 CTCF ZNF654 HCFC1 CHD1 RAD21 FOXA1 SMC3 CUX1 MIR1273A SNORD77B RGS22
GH08I100026 Enhancer 0.4 ENCODE 0.8 -2.3 -2314 0 FOXA2 MAFK FOXA1 MIR1273A PIR62937 RGS22
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1273A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1273A Gene

Genomic Locations for MIR1273A Gene
chr8:100,023,982-100,024,084
(GRCh38/hg38)
Size:
103 bases
Orientation:
Minus strand
chr8:101,036,210-101,036,312
(GRCh37/hg19)

Genomic View for MIR1273A Gene

Genes around MIR1273A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1273A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1273A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1273A Gene

Proteins for MIR1273A Gene

Post-translational modifications for MIR1273A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1273A Gene

Domains & Families for MIR1273A Gene

Gene Families for MIR1273A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1273A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1273A Gene

Function for MIR1273A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1273A Gene

Localization for MIR1273A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1273A Gene

Pathways & Interactions for MIR1273A Gene

SuperPathways for MIR1273A Gene

No Data Available

Interacting Proteins for MIR1273A Gene

Gene Ontology (GO) - Biological Process for MIR1273A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1273A Gene

Drugs & Compounds for MIR1273A Gene

No Compound Related Data Available

Transcripts for MIR1273A Gene

mRNA/cDNA for MIR1273A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1273A Gene

No ASD Table

Relevant External Links for MIR1273A Gene

GeneLoc Exon Structure for
MIR1273A
ECgene alternative splicing isoforms for
MIR1273A

Expression for MIR1273A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1273A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1273A Gene:

MIR1273A
genes like me logo Genes that share expression patterns with MIR1273A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1273A Gene

Orthologs for MIR1273A Gene

Evolution for MIR1273A Gene

ENSEMBL:
Gene Tree for MIR1273A (if available)
TreeFam:
Gene Tree for MIR1273A (if available)

No data available for Orthologs for MIR1273A Gene

Paralogs for MIR1273A Gene

No data available for Paralogs for MIR1273A Gene

Variants for MIR1273A Gene

Sequence variations from dbSNP and Humsavar for MIR1273A Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001362345 -- 100,024,693(-) A/C upstream_transcript_variant
rs1001395138 -- 100,025,057(-) T/C upstream_transcript_variant
rs1001647289 -- 100,025,848(-) C/T upstream_transcript_variant
rs1001929500 -- 100,025,523(-) G/C upstream_transcript_variant
rs1003054964 -- 100,024,217(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1273A Gene

Variant ID Type Subtype PubMed ID
nsv1030482 CNV loss 25217958

Additional Variant Information for MIR1273A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1273A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1273A Gene

Disorders for MIR1273A Gene

Additional Disease Information for MIR1273A

No disorders were found for MIR1273A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1273A Gene

Publications for MIR1273A Gene

  1. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. (PMID: 27423040) Niu X … Nan Y (FEBS letters 2016) 58
  2. miR-1273g-3p participates in acute glucose fluctuation-induced autophagy, dysfunction, and proliferation attenuation in human umbilical vein endothelial cells. (PMID: 26908504) Guo J … Kang Y (American journal of physiology. Endocrinology and metabolism 2016) 58
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 58

Products for MIR1273A Gene

Sources for MIR1273A Gene

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