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Aliases for MIR1266 Gene

Subcategory (RNA class) for MIR1266 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR1266 Gene

  • MicroRNA 1266 2 3 5
  • Hsa-Mir-1266 3
  • Mir-1266 3
  • MIRN1266 3

External Ids for MIR1266 Gene

Previous HGNC Symbols for MIR1266 Gene

  • MIRN1266

Previous GeneCards Identifiers for MIR1266 Gene

  • GC00U923051
  • GC15M050357
  • GC15M052569
  • GC15M052418
  • GC15M052689
  • GC15M054263
  • GC15M054937
  • GC15M055378
  • GC15M055827
  • GC15M056262

Summaries for MIR1266 Gene

Entrez Gene Summary for MIR1266 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1266 Gene

MIR1266 (MicroRNA 1266) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1266 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1266 Gene

Genomics for MIR1266 Gene

GeneHancer (GH) Regulatory Elements for MIR1266 Gene

Promoters and enhancers for MIR1266 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I052651 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 9.8 -375.7 -375681 3.5 PKNOX1 FOXA2 ARID4B SIN3A YY1 FOS NFYC MXD4 REST MEF2D FAM214A GNB5 MIR1266 ENSG00000259935 LOC105370821
GH15I052231 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 11.7 +43.3 43348 5.2 HDGF BACH1 EBF1 BATF IRF4 ZNF366 POLR2A ATF7 ETV6 IKZF2 MYO5C GNB5 MIR1266 TMOD3 FAM214A LOC105370820 GC15M056837 GC15M057316
GH15I052256 Enhancer 1 Ensembl ENCODE 10.8 +20.8 20779 0.8 ZSCAN4 ARID4B IRF4 BRCA1 RAD21 RFX5 TCF12 ZNF766 ZNF143 BCLAF1 MIR1266 GC15M056837 GC15M057316 LOC105370820 MYO5C
GH15I052331 Enhancer 1 Ensembl ENCODE 10.6 -54.5 -54534 0.9 HDGF PKNOX1 CLOCK SIN3A IRF4 RAD21 RFX5 ZNF143 FOS RUNX3 MIR1266 GC15M057423 GC15P052429 MYO5A
GH15I052336 Enhancer 0.9 Ensembl ENCODE 10.7 -60.5 -60524 2 CTCF PKNOX1 HLF MNT RAD21 NFIL3 SP1 JUND GLIS1 NFE2 MIR1266 GC15M057423 GC15P052429 MYO5A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1266 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1266 Gene

Genomic Locations for MIR1266 Gene
chr15:52,277,117-52,277,200
(GRCh38/hg38)
Size:
84 bases
Orientation:
Minus strand
chr15:52,569,314-52,569,397
(GRCh37/hg19)

Genomic View for MIR1266 Gene

Genes around MIR1266 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1266 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1266 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1266 Gene

Proteins for MIR1266 Gene

Post-translational modifications for MIR1266 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1266 Gene

Domains & Families for MIR1266 Gene

Gene Families for MIR1266 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1266: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1266 Gene

Function for MIR1266 Gene

Phenotypes From GWAS Catalog for MIR1266 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1266 Gene

Localization for MIR1266 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1266 Gene

Pathways & Interactions for MIR1266 Gene

SuperPathways for MIR1266 Gene

No Data Available

Interacting Proteins for MIR1266 Gene

Gene Ontology (GO) - Biological Process for MIR1266 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR1266 Gene

Drugs & Compounds for MIR1266 Gene

No Compound Related Data Available

Transcripts for MIR1266 Gene

mRNA/cDNA for MIR1266 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1266 Gene

No ASD Table

Relevant External Links for MIR1266 Gene

GeneLoc Exon Structure for
MIR1266
ECgene alternative splicing isoforms for
MIR1266

Expression for MIR1266 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1266 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1266 Gene:

MIR1266
genes like me logo Genes that share expression patterns with MIR1266: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1266 Gene

Orthologs for MIR1266 Gene

Evolution for MIR1266 Gene

ENSEMBL:
Gene Tree for MIR1266 (if available)
TreeFam:
Gene Tree for MIR1266 (if available)

No data available for Orthologs for MIR1266 Gene

Paralogs for MIR1266 Gene

No data available for Paralogs for MIR1266 Gene

Variants for MIR1266 Gene

Sequence variations from dbSNP and Humsavar for MIR1266 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1001168207 -- 52,277,224(-) G/A upstream_transcript_variant
rs1002259673 -- 52,278,237(-) A/G upstream_transcript_variant
rs1004563070 -- 52,276,802(-) T/A downstream_transcript_variant
rs1004790637 -- 52,278,890(-) T/C upstream_transcript_variant
rs1004933210 -- 52,279,185(-) G/A/C upstream_transcript_variant

Additional Variant Information for MIR1266 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR1266

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR1266 Gene

Disorders for MIR1266 Gene

Additional Disease Information for MIR1266

No disorders were found for MIR1266 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1266 Gene

Publications for MIR1266 Gene

  1. Association of miR-1266 with recurrence/metastasis potential in estrogen receptor positive breast cancer patients. (PMID: 25640367) Sevinc ED … Evrensel T (Asian Pacific journal of cancer prevention : APJCP 2015) 3 58
  2. miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase. (PMID: 24481448) Chen L … Yang SM (Cell death & disease 2014) 3 58
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  5. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58

Products for MIR1266 Gene

Sources for MIR1266 Gene

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