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Aliases for MIR1265 Gene

Subcategory (RNA class) for MIR1265 Gene


Quality Score for this RNA gene is


Aliases for MIR1265 Gene

  • MicroRNA 1265 2 3 5
  • Hsa-Mir-1265 3
  • MIRN1265 3

External Ids for MIR1265 Gene

Previous HGNC Symbols for MIR1265 Gene

  • MIRN1265

Previous GeneCards Identifiers for MIR1265 Gene

  • GC00U922838

Summaries for MIR1265 Gene

Entrez Gene Summary for MIR1265 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR1265 Gene

MIR1265 (MicroRNA 1265) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR1265 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR1265 Gene

Genomics for MIR1265 Gene

GeneHancer (GH) Regulatory Elements for MIR1265 Gene

Promoters and enhancers for MIR1265 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I014395 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -39.5 -39538 2.7 CTCF ZNF362 ELF4 ZNF384 ZBTB40 HIC1 NFIC JUND POLR2A FOS MIR1265 LOC105376425 ENSG00000278100 FRMD4A
GH10I014403 Enhancer 1.1 FANTOM5 ENCODE dbSUPER 11.2 -31.0 -31016 4.5 NCOA3 NFIB ZNF664 CTBP1 GATA3 POLR2A RCOR1 FOS CHD2 TCF7L2 FRMD4A MIR1265 ENSG00000278100
GH10I014381 Enhancer 0.9 ENCODE dbSUPER 11.3 -54.1 -54105 2.8 ZSCAN4 EBF1 BMI1 ZIC2 IRF4 RELA ZNF664 ZFHX2 ATF7 FOS MIR4293 MIR1265 GC10P014349 FRMD4A
GH10I014369 Enhancer 0.5 ENCODE dbSUPER 10.6 -65.3 -65304 3.4 POLR2A MIR1265 MIR4293 GC10P014349 FRMD4A
GH10I014414 Enhancer 0.4 ENCODE dbSUPER 11.5 -20.6 -20608 2.8 MIR1265 FRMD4A ENSG00000278100
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR1265 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR1265 Gene

Genomic Locations for MIR1265 Gene
86 bases
Plus strand

Genomic View for MIR1265 Gene

Genes around MIR1265 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR1265 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR1265 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR1265 Gene

Proteins for MIR1265 Gene

Post-translational modifications for MIR1265 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR1265 Gene

Domains & Families for MIR1265 Gene

Gene Families for MIR1265 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR1265: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR1265 Gene

Function for MIR1265 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR1265 Gene

Localization for MIR1265 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR1265 Gene

Pathways & Interactions for MIR1265 Gene

SuperPathways for MIR1265 Gene

No Data Available

Interacting Proteins for MIR1265 Gene

Gene Ontology (GO) - Biological Process for MIR1265 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR1265 Gene

Drugs & Compounds for MIR1265 Gene

No Compound Related Data Available

Transcripts for MIR1265 Gene

mRNA/cDNA for MIR1265 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR1265 Gene

No ASD Table

Relevant External Links for MIR1265 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR1265 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR1265 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR1265 Gene:

genes like me logo Genes that share expression patterns with MIR1265: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR1265 Gene

Orthologs for MIR1265 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR1265 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1265 34
  • 97 (a)
Species where no ortholog for MIR1265 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR1265 Gene

Gene Tree for MIR1265 (if available)
Gene Tree for MIR1265 (if available)

Paralogs for MIR1265 Gene

No data available for Paralogs for MIR1265 Gene

Variants for MIR1265 Gene

Sequence variations from dbSNP and Humsavar for MIR1265 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1001146711 -- 14,436,850(+) T/A downstream_transcript_variant
rs1002148885 -- 14,435,850(+) G/T upstream_transcript_variant
rs1003178160 -- 14,436,471(+) G/A upstream_transcript_variant
rs1003701906 -- 14,436,335(+) A/T upstream_transcript_variant
rs1005197701 -- 14,436,028(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR1265 Gene

Variant ID Type Subtype PubMed ID
esv34151 CNV loss 18971310
nsv528028 CNV gain 19592680

Additional Variant Information for MIR1265 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR1265 Gene

Disorders for MIR1265 Gene

Additional Disease Information for MIR1265

No disorders were found for MIR1265 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR1265 Gene

Publications for MIR1265 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR1265 Gene

Sources for MIR1265 Gene

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